Pralsetinib for RET fusion-positive non-small-cell lung cancer (ARROW): a multi-cohort, open-label, phase 1/2 study von Gainor, Justin F, Curigliano, Giuseppe, Kim, Dong-Wan, Lee, Dae Ho, Besse, Benjamin, Baik, Christina S, Doebele, Robert C, Cassier, Philippe A, Lopes, Gilberto, Tan, Daniel S W, Garralda, Elena, Paz-Ares, Luis G, Cho, Byoung Chul, Gadgeel, Shirish M, Thomas, Michael, Liu, Stephen V, Taylor, Matthew H, Mansfield, Aaron S, Zhu, Viola W, Clifford, Corinne, Zhang, Hui, Palmer, Michael, Green, Jennifer, Turner, Christopher D, Subbiah, Vivek

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Ponatinib in Refractory Philadelphia Chromosome–Positive Leukemias von Cortes, Jorge E, Kantarjian, Hagop, Shah, Neil P, Bixby, Dale, Mauro, Michael J, Flinn, Ian, O'Hare, Thomas, Hu, Simin, Narasimhan, Narayana I, Rivera, Victor M, Clackson, Tim, Turner, Christopher D, Haluska, Frank G, Druker, Brian J, Deininger, Michael W.N, Talpaz, Moshe

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Alleviating monoterpene toxicity using a two-phase extractive fermentation for the bioproduction of jet fuel mixtures in Saccharomyces cerevisiae von Brennan, Timothy C.R., Turner, Christopher D., Krömer, Jens O., Nielsen, Lars K.

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Late Effects of Therapy for Pediatric Brain Tumor Survivors von Turner, Christopher D., Rey-Casserly, Celiane, Liptak, Cori C., Chordas, Christine

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Intensive Multimodality Treatment for Children With Newly Diagnosed CNS Atypical Teratoid Rhabdoid Tumor von CHI, Susan N, ZIMMERMAN, Mary Ann, GOLDMAN, Stewart, MANLEY, Peter E, BOWERS, Daniel C, BENDEL, Anne, RUBIN, Joshua, TURNER, Christopher D, MARCUS, Karen J, GOUMNEROVA, Liliana, ULLRICH, Nicole J, KIERAN, Mark W, XIAOPAN YAO, COHEN, Kenneth J, BURGER, Peter, BIEGEL, Jaclyn A, RORKE-ADAMS, Lucy B, FISHER, Michael J, JANSS, Anna, MAZEWSKI, Claire

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A Phase II Study of Glembatumumab Vedotin for Metastatic Uveal Melanoma von Hasanov, Merve, Rioth, Matthew J, Kendra, Kari, Hernandez-Aya, Leonel, Joseph, Richard W, Williamson, Stephen, Chandra, Sunandana, Shirai, Keisuke, Turner, Christopher D, Lewis, Karl, Crowley, Elizabeth, Moscow, Jeffrey, Carter, Brett, Patel, Sapna

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Glembatumumab vedotin for patients with metastatic, gpNMB overexpressing, triple-negative breast cancer (“METRIC”): a randomized multicenter study von Vahdat, Linda T., Schmid, Peter, Forero-Torres, Andres, Blackwell, Kimberly, Telli, Melinda L., Melisko, Michelle, Möbus, Volker, Cortes, Javier, Montero, Alberto J., Ma, Cynthia, Nanda, Rita, Wright, Gail S., He, Yi, Hawthorne, Thomas, Bagley, Rebecca G., Halim, Abdel-Baset, Turner, Christopher D., Yardley, Denise A.

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Pralsetinib for patients with advanced or metastatic RET-altered thyroid cancer (ARROW): a multi-cohort, open-label, registrational, phase 1/2 study von Subbiah, Vivek, Hu, Mimi I, Wirth, Lori J, Schuler, Martin, Mansfield, Aaron S, Curigliano, Giuseppe, Brose, Marcia S, Zhu, Viola W, Leboulleux, Sophie, Bowles, Daniel W, Baik, Christina S, Adkins, Douglas, Keam, Bhumsuk, Matos, Ignacio, Garralda, Elena, Gainor, Justin F, Lopes, Gilberto, Lin, Chia-Chi, Godbert, Yann, Sarker, Debashis, Miller, Stephen G, Clifford, Corinne, Zhang, Hui, Turner, Christopher D, Taylor, Matthew H

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Rindopepimut with Bevacizumab for Patients with Relapsed EGFRvIII-Expressing Glioblastoma (ReACT): Results of a Double-Blind Randomized Phase II Trial von Reardon, David A, Desjardins, Annick, Vredenburgh, James J, O'Rourke, Donald M, Tran, David D, Fink, Karen L, Nabors, Louis B, Li, Gordon, Bota, Daniela A, Lukas, Rimas V, Ashby, Lynn S, Duic, J Paul, Mrugala, Maciej M, Cruickshank, Scott, Vitale, Laura, He, Yi, Green, Jennifer A, Yellin, Michael J, Turner, Christopher D, Keler, Tibor, Davis, Thomas A, Sampson, John H

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Evaluation of the Effect of Multiple Doses of Lansoprazole on the Pharmacokinetics and Safety of Ponatinib in Healthy Subjects von Narasimhan, Narayana I., Dorer, David J., Davis, Jeffrey, Turner, Christopher D., Sonnichsen, Daryl

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Phase I and Pharmacokinetic Study of the Oral Farnesyltransferase Inhibitor Lonafarnib Administered Twice Daily to Pediatric Patients With Advanced Central Nervous System Tumors Us... von KIERAN, Mark W, PACKER, Roger J, TURNER, Christopher D, BELASCO, Jean B, BRONISCER, Alberto, YALI ZHU, FRANK, Emily, KIRSCHMEIER, Paul, STATKEVICH, Paul, YVER, Antoine, BOYETT, James M, KUN, Larry E, ONAR, Arzu, BLANEY, Susan M, PHILLIPS, Peter, POLLACK, Ian F, GEYER, J. Russell, GURURANGAN, Sri, BANERJEE, Anu, GOLDMAN, Stewart

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A phase 2 study of glembatumumab vedotin, an antibody‐drug conjugate targeting glycoprotein NMB, in patients with advanced melanoma von Ott, Patrick A., Pavlick, Anna C., Johnson, Douglas B., Hart, Lowell L., Infante, Jeffrey R., Luke, Jason J., Lutzky, Jose, Rothschild, Neal E., Spitler, Lynn E., Cowey, C. Lance, Alizadeh, Aaron R., Salama, April K., He, Yi, Hawthorne, Thomas R., Bagley, Rebecca G., Zhang, Joshua, Turner, Christopher D., Hamid, Omid

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A phase II trial of a multi-agent oral antiangiogenic (metronomic) regimen in children with recurrent or progressive cancer von Robison, Nathan J., Campigotto, Federico, Chi, Susan N., Manley, Peter E., Turner, Christopher D., Zimmerman, Mary Ann, Chordas, Christine A., Werger, Annette M., Allen, Jeffrey C., Goldman, Stewart, Rubin, Joshua B., Isakoff, Michael S., Pan, Wilbur J., Khatib, Ziad A., Comito, Melanie A., Bendel, Anne E., Pietrantonio, Jay B., Kondrat, Laura, Hubbs, Shannon M., Neuberg, Donna S., Kieran, Mark W.

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Ponatinib in patients with refractory acute myeloid leukaemia: findings from a phase 1 study von Shah, Neil P., Talpaz, Moshe, Deininger, Michael W. N., Mauro, Michael J., Flinn, Ian W., Bixby, Dale, Lustgarten, Stephanie, Gozgit, Joseph M., Clackson, Tim, Turner, Christopher D., Haluska, Frank G., Kantarjian, Hagop, Cortes, Jorge E.

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Phase I Trial of VNP40101M (Cloretazine) in Children with Recurrent Brain Tumors: A Pediatric Brain Tumor Consortium Study von Gururangan, Sridharan, Turner, Christopher D, Stewart, Clinton F, O'Shaughnessy, Melinda, Kocak, Mehmet, Poussaint, Tina Young, Phillips, Peter C, Goldman, Stewart, Packer, Roger, Pollack, Ian F, Blaney, Susan M, Karsten, Verena, Gerson, Stanton L, Boyett, James M, Friedman, Henry S, Kun, Larry E

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Go, no-go decision making for phase 3 clinical trials: ACT IV revisited – Authors' reply von Weller, Michael, Butowski, Nicholas, Tran, David D, Recht, Lawrence D, Lim, Michael, Hirte, Hal, Ashby, Lynn, Mechtler, Laszlo, Goldlust, Samuel A, Iwamoto, Fabio, Drappatz, Jan, O'Rourke, Donald M, Wong, Mark, Hamilton, Mark G, Finocchiaro, Gaetano, Perry, James, Wick, Wolfgang, Green, Jennifer, He, Yi, Turner, Christopher D, Yellin, Michael J, Keler, Tibor, Davis, Thomas A, Stupp, Roger, Sampson, John H

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Evaluation of pharmacokinetics and safety of ponatinib in subjects with chronic hepatic impairment and matched healthy subjects von Narasimhan, Narayana I., Dorer, David J., Davis, Jeffrey, Turner, Christopher D., Marbury, Thomas C., Sonnichsen, Daryl

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A Multicenter, First-in-Pediatrics, Phase 1, Pharmacokinetic and Pharmacodynamic Study of Ridaforolimus in Patients with Refractory Solid Tumors von GORE, Lia, TRIPPETT, Tanya M, TURNER, Christopher D, HALUSKA, Frank G, NIEDER, Michael, KATZENSTEIN, Howard M, BOKLAN, Jessica, NARENDRAN, Aru, SMITH, Amy, MACY, Margaret E, ROLLA, Katherine, NARASHIMHAN, Narayana, SQUILLACE, Rachel M

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A feasibility trial of antiangiogenic (metronomic) chemotherapy in pediatric patients with recurrent or progressive cancer von Kieran, Mark W, Turner, Christopher D, Rubin, Joshua B, Chi, Susan N, Zimmerman, Mary Ann, Chordas, Christine, Klement, Giannoula, Laforme, Andrea, Gordon, Amanda, Thomas, Amanda, Neuberg, Donna, Browder, Timothy, Folkman, Judah

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Analysis of the potential effect of ponatinib on the QTc interval in patients with refractory hematological malignancies von Sonnichsen, Daryl, Dorer, David J., Cortes, Jorge, Talpaz, Moshe, Deininger, Michael W., Shah, Neil P., Kantarjian, Hagop M., Bixby, Dale, Mauro, Michael J., Flinn, Ian W., Litwin, Jeffrey, Turner, Christopher D., Haluska, Frank G.

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