Structural insight into small molecule action on Frizzleds von Kozielewicz, Paweł, Turku, Ainoleena, Bowin, Carl-Fredrik, Petersen, Julian, Valnohova, Jana, Cañizal, Maria Consuelo Alonso, Ono, Yuki, Inoue, Asuka, Hoffmann, Carsten, Schulte, Gunnar

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Residue 6.43 defines receptor function in class F GPCRs von Turku, Ainoleena, Schihada, Hannes, Kozielewicz, Pawel, Bowin, Carl-Fredrik, Schulte, Gunnar

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Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs von Xu, Lu, Chen, Bo, Schihada, Hannes, Wright, Shane C., Turku, Ainoleena, Wu, Yiran, Han, Gye-Won, Kowalski-Jahn, Maria, Kozielewicz, Pawel, Bowin, Carl-Fredrik, Zhang, Xianjun, Li, Chao, Bouvier, Michel, Schulte, Gunnar, Xu, Fei

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Pharmacophore Model To Discover OX1 and OX2 Orexin Receptor Ligands von Turku, Ainoleena, Borrel, Alexandre, Leino, Teppo O, Karhu, Lasse, Kukkonen, Jyrki P, Xhaard, Henri

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Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity von Turku, Ainoleena, Rinne, Maiju K, Boije Af Gennäs, Gustav, Xhaard, Henri, Lindholm, Dan, Kukkonen, Jyrki P

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Modeling of the OX1R-orexin-A complex suggests two alternative binding modes von Karhu, Lasse, Turku, Ainoleena, Xhaard, Henri

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Structure–Activity Relationships of 1‐Benzoylazulenes at the OX1 and OX2 Orexin Receptors von Turku, Ainoleena, Leino, Teppo O., Karhu, Lasse, Yli‐Kauhaluoma, Jari, Kukkonen, Jyrki P., Wallén, Erik A. A., Xhaard, Henri

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Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C von Provenzani, Riccardo, Tarvainen, Ilari, Brandoli, Giulia, Lempinen, Antti, Artes, Sanna, Turku, Ainoleena, Jäntti, Maria Helena, Talman, Virpi, Yli-Kauhaluoma, Jari, Tuominen, Raimo K, Boije Af Gennäs, Gustav

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SpaceHASTEN: A Structure-Based Virtual Screening Tool for Nonenumerated Virtual Chemical Libraries von Kalliokoski, Tuomo, Turku, Ainoleena, Käsnänen, Heikki

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Insights into the mechanism of membrane pyrophosphatases by combining experiment and computer simulation von Shah, Nita R., Wilkinson, Craig, Harborne, Steven P. D., Turku, Ainoleena, Li, Kun-Mou, Sun, Yuh-Ju, Harris, Sarah, Goldman, Adrian

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Molecular Pharmacology of Class F Receptor Activation von Kozielewicz, Pawel, Turku, Ainoleena, Schulte, Gunnar

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Deconvolution of WNT-induced Frizzled conformational dynamics with fluorescent biosensors von Schihada, Hannes, Kowalski-Jahn, Maria, Turku, Ainoleena, Schulte, Gunnar

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A NanoBRET-Based Binding Assay for Smoothened Allows Real-time Analysis of Ligand Binding and Distinction of Two Binding Sites for BODIPY-cyclopamine von Kozielewicz, Paweł, Bowin, Carl-Fredrik, Turku, Ainoleena, Schulte, Gunnar

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Pharmacophore Model To Discover OX 1 and OX 2 Orexin Receptor Ligands von Turku, Ainoleena, Borrel, Alexandre, Leino, Teppo O., Karhu, Lasse, Kukkonen, Jyrki P., Xhaard, Henri

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Azulene as a biphenyl mimetic in orexin/hypocretin receptor agonists von Leino, Teppo O., Turku, Ainoleena, Urvas, Lauri, Adhikari, Karuna, Oksanen, Jouni, Steynen, Yana, Yli-Kauhaluoma, Jari, Xhaard, Henri, Kukkonen, Jyrki P., Wallén, Erik A.A.

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Azulene-based compounds for targeting orexin receptors von Leino, Teppo O., Turku, Ainoleena, Yli-Kauhaluoma, Jari, Kukkonen, Jyrki P., Xhaard, Henri, Wallén, Erik A.A.

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Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G s von Xu, Lu, Chen, Bo, Schihada, Hannes, Wright, Shane C, Turku, Ainoleena, Wu, Yiran, Han, Gye-Won, Kowalski-Jahn, Maria, Kozielewicz, Pawel, Bowin, Carl-Fredrik, Zhang, Xianjun, Li, Chao, Bouvier, Michel, Schulte, Gunnar, Xu, Fei

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Frizzled BRET sensors based on bioorthogonal labeling of unnatural amino acids reveal WNT-induced dynamics of the cysteine-rich domain von Kowalski-Jahn, Maria, Schihada, Hannes, Turku, Ainoleena, Huber, Thomas, Sakmar, Thomas P, Schulte, Gunnar

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Pharmacological characterization of the orexin/hypocretin receptor agonist Nag 26 von Rinne, Maiju K., Leino, Teppo O., Turku, Ainoleena, Turunen, Pauli M., Steynen, Yana, Xhaard, Henri, Wallén, Erik A.A., Kukkonen, Jyrki P.

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Scaffold hopping from von Provenzani, Riccardo, Tarvainen, Ilari, Brandoli, Giulia, Lempinen, Antti, Artes, Sanna, Turku, Ainoleena, Jäntti, Maria Helena, Talman, Virpi, Yli-Kauhaluoma, Jari, Tuominen, Raimo K, Boije af Gennäs, Gustav

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