The future of cancer therapy: selecting patients likely to respond to PD1/L1 blockade von Ribas, Antoni, Tumeh, Paul C

Volltext

Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations von Shin, Daniel Sanghoon, Zaretsky, Jesse M, Escuin-Ordinas, Helena, Garcia-Diaz, Angel, Hu-Lieskovan, Siwen, Kalbasi, Anusha, Grasso, Catherine S, Hugo, Willy, Sandoval, Salemiz, Torrejon, Davis Y, Palaskas, Nicolaos, Rodriguez, Gabriel Abril, Parisi, Giulia, Azhdam, Ariel, Chmielowski, Bartosz, Cherry, Grace, Seja, Elizabeth, Berent-Maoz, Beata, Shintaku, I Peter, Le, Dung T, Pardoll, Drew M, Diaz, Jr, Luis A, Tumeh, Paul C, Graeber, Thomas G, Lo, Roger S, Comin-Anduix, Begoña, Ribas, Antoni

Volltext

Immunotherapy Resistance by Inflammation-Induced Dedifferentiation von Mehta, Arnav, Kim, Yeon Joo, Robert, Lidia, Tsoi, Jennifer, Comin-Anduix, Begoña, Berent-Maoz, Beata, Cochran, Alistair J, Economou, James S, Tumeh, Paul C, Puig-Saus, Cristina, Ribas, Antoni

Volltext

PD-1 blockade induces responses by inhibiting adaptive immune resistance von Tumeh, Paul C., Harview, Christina L., Yearley, Jennifer H., Shintaku, I. Peter, Taylor, Emma J. M., Robert, Lidia, Chmielowski, Bartosz, Spasic, Marko, Henry, Gina, Ciobanu, Voicu, West, Alisha N., Carmona, Manuel, Kivork, Christine, Seja, Elizabeth, Cherry, Grace, Gutierrez, Antonio J., Grogan, Tristan R., Mateus, Christine, Tomasic, Gorana, Glaspy, John A., Emerson, Ryan O., Robins, Harlan, Pierce, Robert H., Elashoff, David A., Robert, Caroline, Ribas, Antoni

Volltext

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma von Zaretsky, Jesse M, Garcia-Diaz, Angel, Shin, Daniel S, Escuin-Ordinas, Helena, Hugo, Willy, Hu-Lieskovan, Siwen, Torrejon, Davis Y, Abril-Rodriguez, Gabriel, Sandoval, Salemiz, Barthly, Lucas, Saco, Justin, Homet Moreno, Blanca, Mezzadra, Riccardo, Chmielowski, Bartosz, Ruchalski, Kathleen, Shintaku, I. Peter, Sanchez, Phillip J, Puig-Saus, Cristina, Cherry, Grace, Seja, Elizabeth, Kong, Xiangju, Pang, Jia, Berent-Maoz, Beata, Comin-Anduix, Begoña, Graeber, Thomas G, Tumeh, Paul C, Schumacher, Ton N.M, Lo, Roger S, Ribas, Antoni

Volltext

MAPK Signaling and Inflammation Link Melanoma Phenotype Switching to Induction of CD73 during Immunotherapy von Reinhardt, Julia, Landsberg, Jennifer, Schmid-Burgk, Jonathan L, Ramis, Bartomeu Bibiloni, Bald, Tobias, Glodde, Nicole, Lopez-Ramos, Dorys, Young, Arabella, Ngiow, Shin Foong, Nettersheim, Daniel, Schorle, Hubert, Quast, Thomas, Kolanus, Waldemar, Schadendorf, Dirk, Long, Georgina V, Madore, Jason, Scolyer, Richard A, Ribas, Antoni, Smyth, Mark J, Tumeh, Paul C, Tüting, Thomas, Hölzel, Michael

Volltext

BRAF Inhibitor Vemurafenib Improves the Antitumor Activity of Adoptive Cell Immunotherapy von KOYA, Richard C, MOK, Stephen, RIBAS, Antoni, OTTE, Nicholas, BLACKETOR, Kevin J, COMIN-ANDUIX, Begonya, TUMEH, Paul C, MINASYAN, Aspram, GRAHAM, Nicholas A, GRAEBER, Thomas G, CHODON, Thinle

Volltext

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma von Hamid, Omid, Robert, Caroline, Daud, Adil, Hodi, F. Stephen, Hwu, Wen-Jen, Kefford, Richard, Wolchok, Jedd D, Hersey, Peter, Joseph, Richard W, Weber, Jeffrey S, Dronca, Roxana, Gangadhar, Tara C, Patnaik, Amita, Zarour, Hassane, Joshua, Anthony M, Gergich, Kevin, Elassaiss-Schaap, Jeroen, Algazi, Alain, Mateus, Christine, Boasberg, Peter, Tumeh, Paul C, Chmielowski, Bartosz, Ebbinghaus, Scot W, Li, Xiaoyun Nicole, Kang, S. Peter, Ribas, Antoni

Volltext

PD-1 Blockade Expands Intratumoral Memory T Cells von Ribas, Antoni, Shin, Daniel Sanghoon, Zaretsky, Jesse, Frederiksen, Juliet, Cornish, Andrew, Avramis, Earl, Seja, Elizabeth, Kivork, Christine, Siebert, Janet, Kaplan-Lefko, Paula, Wang, Xiaoyan, Chmielowski, Bartosz, Glaspy, John A, Tumeh, Paul C, Chodon, Thinle, Pe'er, Dana, Comin-Anduix, Begoña

Volltext

Evaluation of clinicopathological factors in PD-1 response: derivation and validation of a prediction scale for response to PD-1 monotherapy von Nosrati, Adi, Tsai, Katy K, Goldinger, Simone M, Tumeh, Paul, Grimes, Barbara, Loo, Kimberly, Algazi, Alain P, Nguyen-Kim, Thi Dan Linh, Levesque, Mitchell, Dummer, Reinhard, Hamid, Omid, Daud, Adil

Volltext

Phase I Trial of Intratumoral Injection of CCL21 Gene-Modified Dendritic Cells in Lung Cancer Elicits Tumor-Specific Immune Responses and CD8 + T-cell Infiltration von Lee, Jay M, Lee, Mi-Heon, Garon, Edward, Goldman, Jonathan W, Salehi-Rad, Ramin, Baratelli, Felicita E, Schaue, Dörthe, Wang, Gerald, Rosen, Fran, Yanagawa, Jane, Walser, Tonya C, Lin, Ying, Park, Stacy J, Adams, Sharon, Marincola, Francesco M, Tumeh, Paul C, Abtin, Fereidoun, Suh, Robert, Reckamp, Karen L, Lee, Gina, Wallace, William D, Lee, Sarah, Zeng, Gang, Elashoff, David A, Sharma, Sherven, Dubinett, Steven M

Volltext

Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC von Tumeh, Paul C, Hellmann, Matthew D, Hamid, Omid, Tsai, Katy K, Loo, Kimberly L, Gubens, Matthew A, Rosenblum, Michael, Harview, Christina L, Taube, Janis M, Handley, Nathan, Khurana, Neharika, Nosrati, Adi, Krummel, Matthew F, Tucker, Andrew, Sosa, Eduardo V, Sanchez, Phillip J, Banayan, Nooriel, Osorio, Juan C, Nguyen-Kim, Dan L, Chang, Jeremy, Shintaku, I Peter, Boasberg, Peter D, Taylor, Emma J, Munster, Pamela N, Algazi, Alain P, Chmielowski, Bartosz, Dummer, Reinhard, Grogan, Tristan R, Elashoff, David, Hwang, Jimmy, Goldinger, Simone M, Garon, Edward B, Pierce, Robert H, Daud, Adil

Volltext

Characteristic purpura of the ears, vasculitis, and neutropenia–a potential public health epidemic associated with levamisole-adulterated cocaine von Chung, Catherine, MD, Tumeh, Paul C., MD, Birnbaum, Ron, MD, Tan, Belinda H., MD, PhD, Sharp, Linda, MD, McCoy, Erin, MD, Mercurio, Mary Gail, MD, Craft, Noah, MD, PhD, DTM&H

Volltext

Infiltration of CD8 T Cells and Expression of PD-1 and PD-L1 in Synovial Sarcoma von Nowicki, Theodore S, Akiyama, Ryan, Huang, Rong Rong, Shintaku, I Peter, Wang, Xiaoyan, Tumeh, Paul C, Singh, Arun, Chmielowski, Bartosz, Denny, Christopher, Federman, Noah, Ribas, Antoni

Volltext

Cancer therapy: Tumours switch to resist von Ribas, Antoni, Tumeh, Paul C

Volltext

Distinct immunological mechanisms of CTLA-4 and PD-1 blockade revealed by analyzing TCR usage in blood lymphocytes von Robert, Lidia, Harview, Christina, Emerson, Ryan, Wang, Xiaoyan, Mok, Stephen, Homet, Blanca, Comin-Anduix, Begonya, Koya, Richard C, Robins, Harlan, Tumeh, Paul C, Ribas, Antoni

Volltext

Tumours switch to resist von Ribas, Antoni, Tumeh, Paul C.

Volltext

PET Imaging of Cancer Immunotherapy von Tumeh, Paul C, Radu, Caius G, Ribas, Antoni

Volltext

Enhanced skin toxicity with concurrent ipilimumab and radiation in vaginal/vulvar melanoma: a case report and literature review von Mesko, Shane, Konecny, Gottfried E, Tumeh, Paul C, Kamrava, Mitchell

Volltext

The Impact of Ex Vivo Clinical Grade Activation Protocols on Human T-cell Phenotype and Function for the Generation of Genetically Modified Cells for Adoptive Cell Transfer Therapy von TUMEH, Paul C, KOYA, Richard C, CHODON, Thinle, GRAHAM, Nicholas A, GRAEBER, Thomas G, COMIN-ANDUIX, Begoña, RIBAS, Antoni

Volltext