Tumor Growth Inhibition by Olaparib in BRCA2 Germline-Mutated Patient-Derived Ovarian Cancer Tissue Xenografts von KORTMANN, Ursula, MCALPINE, Jessica N, HUNTSMAN, David G, YUZHUO WANG, BLAKE GILKS, C, HUI XUE, JUN GUAN, GAVIN HA, TULLY, Sophie, SHAFAIT, Sharaz, LAU, Alan, CRANSTON, Aaron N, O'CONNOR, Mark J

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5-Benzamidoisoquinolin-1-ones and 5-(ω-Carboxyalkyl)isoquinolin-1-ones as Isoform-Selective Inhibitors of Poly(ADP-ribose) Polymerase 2 (PARP-2) von Sunderland, Peter T, Woon, Esther C. Y, Dhami, Archana, Bergin, Aoife B, Mahon, Mary F, Wood, Pauline J, Jones, Louise A, Tully, Sophie R, Lloyd, Matthew D, Thompson, Andrew S, Javaid, Hashim, Martin, Niall M. B, Threadgill, Michael D

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Synthesis of 4-alkyl-, 4-aryl- and 4-arylamino-5-aminoisoquinolin-1-ones and identification of a new PARP-2 selective inhibitor von Sunderland, Peter T, Dhami, Archana, Mahon, Mary F, Jones, Louise A, Tully, Sophie R, Lloyd, Matthew D, Thompson, Andrew S, Javaid, Hashim, Martin, Niall M B, Threadgill, Michael D

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5-benzamidoisoquinolin-1-ones and 5-(ω-carboxyalkyl)isoquinolin-1-ones as isoform-selective inhibitors of poly(ADP-ribose) polymerase 2 (PARP-2) von Sunderland, Peter T, Woon, Esther C Y, Dhami, Archana, Bergin, Aoife B, Mahon, Mary F, Wood, Pauline J, Jones, Louise A, Tully, Sophie R, Lloyd, Matthew D, Thompson, Andrew S, Javaid, Hashim, Martin, Niall M B, Threadgill, Michael D

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Synthesis of 4-alkyl-, 4-aryl- and 4-arylamino-5-aminoisoquinolin-1-ones and identification of a new PARP-2 selective inhibitorCCDC reference numbers 781105 (26a), 781106 (33) and... von Sunderland, Peter T, Dhami, Archana, Mahon, Mary F, Jones, Louise A, Tully, Sophie R, Lloyd, Matthew D, Thompson, Andrew S, Javaid, Hashim, Martin, Niall M. B, Threadgill, Michael D

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Linkage-specific ubiquitin binding interfaces modulate the activity of the chlamydial deubiquitinase Cdu1 towards poly-ubiquitin substrates von Schlötzer, Jan, Schmalix, Alexander, Hügelschäffer, Sophie, Rieger, Dominic, Sauer, Florian, Tully, Mark D, Rudel, Thomas, Wiesner, Silke, Kisker, Caroline

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Effectiveness of isolation, testing, contact tracing, and physical distancing on reducing transmission of SARS-CoV-2 in different settings: a mathematical modelling study von Kucharski, Adam J, Klepac, Petra, Conlan, Andrew J K, Kissler, Stephen M, Tang, Maria L, Fry, Hannah, Gog, Julia R, Edmunds, W John, Emery, Jon C, Medley, Graham, Munday, James D, Russell, Timothy W, Leclerc, Quentin J, Diamond, Charlie, Procter, Simon R, Gimma, Amy, Sun, Fiona Yueqian, Gibbs, Hamish P, Rosello, Alicia, van Zandvoort, Kevin, Hué, Stéphane, Meakin, Sophie R, Deol, Arminder K, Knight, Gwen, Jombart, Thibaut, Foss, Anna M, Bosse, Nikos I, Atkins, Katherine E, Quilty, Billy J, Lowe, Rachel, Prem, Kiesha, Flasche, Stefan, Pearson, Carl A B, Houben, Rein M G J, Nightingale, Emily S, Endo, Akira, Tully, Damien C, Liu, Yang, Villabona-Arenas, Julian, O'Reilly, Kathleen, Funk, Sebastian, Eggo, Rosalind M, Jit, Mark, Rees, Eleanor M, Hellewell, Joel, Clifford, Samuel, Jarvis, Christopher I, Abbott, Sam, Auzenbergs, Megan, Davies, Nicholas G, Simons, David

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Maternal BMI as a predictor of methylation of obesity-related genes in saliva samples from preschool-age Hispanic children at-risk for obesity von Oelsner, Kathryn Tully, Guo, Yan, To, Sophie Bao-Chieu, Non, Amy L, Barkin, Shari L

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The impact of non-pharmaceutical interventions on SARS-CoV-2 transmission across 130 countries and territories von Liu, Yang, Morgenstern, Christian, Kelly, James, Lowe, Rachel, Jit, Mark

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Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7 von Davies, Nicholas G., Jarvis, Christopher I., Edmunds, W. John, Jewell, Nicholas P., Diaz-Ordaz, Karla, Keogh, Ruth H.

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Enhanced structure/function of mTSPO translocator in lipid:surfactant mixed micelles von Saade, Christelle, Pozza, Alexandre, Bonneté, Françoise, Finet, Stéphanie, Lutz-Bueno, Viviane, Tully, Mark D., Varela, Paloma F., Lacapère, Jean-Jacques, Combet, Sophie

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Measuring the effects of COVID-19-related disruption on dengue transmission in southeast Asia and Latin America: a statistical modelling study von Chen, Yuyang, Li, Naizhe, Lourenço, José, Wang, Lin, Cazelles, Bernard, Dong, Lu, Li, Bingying, Liu, Yang, Jit, Mark, Bosse, Nikos I, Abbott, Sam, Velayudhan, Raman, Wilder-Smith, Annelies, Tian, Huaiyu, Brady, Oliver J, Procter, Simon R, Wong, Kerry LM, Hellewell, Joel, Davies, Nicholas G, Jarvis, Christopher I, McCarthy, Ciara V, Medley, Graham, Meakin, Sophie R, Rosello, Alicia, Finch, Emilie, Lowe, Rachel, Pearson, Carl A B, Clifford, Samuel, Quilty, Billy J, Flasche, Stefan, Gibbs, Hamish P, Chapman, Lloyd A C, Atkins, Katherine E., Hodgson, David, Barnard, Rosanna C, Russell, Timothy W, Klepac, Petra, Jafari, Yalda, Eggo, Rosalind M, Mee, Paul, Quaife, Matthew, Endo, Akira, Funk, Sebastian, Hué, Stéphane, Kucharski, Adam J, Edmunds, W John, O'Reilly, Kathleen, Pung, Rachael, Villabona-Arenas, C Julian, Gimma, Amy, Abbas, Kaja, Prem, Kiesha, Knight, Gwenan M, Sun, Fiona Yueqian, Waites, William, Munday, James D, Koltai, Mihaly, Sandmann, Frank G, Tully, Damien C

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Using a real-world network to model localized COVID-19 control strategies von Firth, Josh A., Hellewell, Joel, Klepac, Petra, Kissler, Stephen, Kucharski, Adam J., Spurgin, Lewis G.

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COVID-19 Crisis Reduces Free Tropospheric Ozone Across the Northern Hemisphere von Steinbrecht, Wolfgang, Kubistin, Dagmar, Plass-Dülmer, Christian, Davies, Jonathan, Gathen, Peter Von Der, Deckelmann, Holger, Jepsen, Nis, Kivi, Rigel, Lyall, Norrie, Palm, Matthias, Notholt, Justus, Kois, Bogumil, Oelsner, Peter, Allaart, Marc, Piters, Ankie, Gill, Michael, Malderen, Roeland Van, Delcloo, Andy W., Sussmann, Ralf, Mahieu, Emmanuel, Servais, Christian, Romanens, Gonzague, Stübi, Rene, Ancellet, Gerard, Godin-Beekmann, Sophie, Yamanouchi, Shoma, Strong, Kimberly, Johnson, Bryan, Cullis, Patrick, Petropavlovskikh, Irina, Chouza, Fernando, Leblanc, Thierry, Strahan, Susan, Stauffer, Ryan M., Thompson, Anne M.

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The potential health and economic value of SARS-CoV-2 vaccination alongside physical distancing in the UK: a transmission model-based future scenario analysis and economic evaluati... von Sandmann, Frank G, Davies, Nicholas G, Vassall, Anna, Edmunds, W John, Jit, Mark, Sun, Fiona Yueqian, Villabona-Arenas, C Julian, Nightingale, Emily S, Showering, Alicia, Knight, Gwenan M, Sherratt, Katharine, Liu, Yang, Abbas, Kaja, Funk, Sebastian, Endo, Akira, Hellewell, Joel, Rosello, Alicia, Lowe, Rachel, Quaife, Matthew, Gimma, Amy, Brady, Oliver, Williams, Jack, Procter, Simon R, Eggo, Rosalind M, Chan, Yung-Wai Desmond, Munday, James D, Barnard, Rosanna C, Gore-Langton, Georgia R, Bosse, Nikos I, Waterlow, Naomi R, Diamond, Charlie, Russell, Timothy W, Medley, Graham, Flasche, Stefan, Atkins, Katherine E, Prem, Kiesha, Simons, David, Auzenbergs, Megan, Tully, Damien C, Jarvis, Christopher I, van Zandvoort, Kevin, Abbott, Sam, Pearson, Carl A B, Jombart, Thibaut, Meakin, Sophie R, Foss, Anna M, Kucharski, Adam J, Quilty, Billy J, Gibbs, Hamish P, Clifford, Samuel, Klepac, Petra

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Ozone profile retrieval from nadir TROPOMI measurements in the UV range von Mettig, Nora, Weber, Mark, Rozanov, Alexei, Arosio, Carlo, Burrows, John P, Veefkind, Pepijn, Thompson, Anne M, Querel, Richard, Leblanc, Thierry, Godin-Beekmann, Sophie, Kivi, Rigel, Tully, Matthew B

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Projecting contact matrices in 177 geographical regions: An update and comparison with empirical data for the COVID-19 era von Prem, Kiesha, Zandvoort, Kevin van, Klepac, Petra, Eggo, Rosalind M, Davies, Nicholas G, Cook, Alex R, Jit, Mark

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Reconstructing the early global dynamics of under-ascertained COVID-19 cases and infections von Russell, Timothy W, Golding, Nick, Hellewell, Joel, Abbott, Sam, Wright, Lawrence, Pearson, Carl A B, van Zandvoort, Kevin, Jarvis, Christopher I, Gibbs, Hamish, Liu, Yang, Eggo, Rosalind M, Edmunds, W John, Kucharski, Adam J

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Changing travel patterns in China during the early stages of the COVID-19 pandemic von Gibbs, Hamish, Liu, Yang, Pearson, Carl A. B., Jarvis, Christopher I., Grundy, Chris, Quilty, Billy J., Diamond, Charlie, Eggo, Rosalind M.

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A rapid bead-based radioligand binding assay for the determination of target-binding fraction and quality control of radiopharmaceuticals von Sharma, Sai Kiran, Lyashchenko, Serge K., Park, Hijin A., Pillarsetty, Nagavarakishore, Roux, Yorann, Wu, Jiong, Poty, Sophie, Tully, Kathryn M., Poirier, John T., Lewis, Jason S.

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