Integrative random forest for gene regulatory network inference von Petralia, Francesca, Wang, Pei, Yang, Jialiang, Tu, Zhidong

Volltext

Multiscale causal networks identify VGF as a key regulator of Alzheimer’s disease von Beckmann, Noam D., Lin, Wei-Jye, Wang, Minghui, Cohain, Ariella T., Charney, Alexander W., Wang, Pei, Ma, Weiping, Wang, Ying-Chih, Jiang, Cheng, Audrain, Mickael, Comella, Phillip H., Fakira, Amanda K., Hariharan, Siddharth P., Belbin, Gillian M., Girdhar, Kiran, Levey, Allan I., Seyfried, Nicholas T., Dammer, Eric B., Duong, Duc, Lah, James J., Haure-Mirande, Jean-Vianney, Shackleton, Ben, Fanutza, Tomas, Blitzer, Robert, Kenny, Eimear, Zhu, Jun, Haroutunian, Vahram, Katsel, Pavel, Gandy, Sam, Tu, Zhidong, Ehrlich, Michelle E., Zhang, Bin, Salton, Stephen R., Schadt, Eric E.

Volltext

An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease von Cohain, Ariella T., Barrington, William T., Jordan, Daniel M., Beckmann, Noam D., Argmann, Carmen A., Houten, Sander M., Charney, Alexander W., Ermel, Raili, Sukhavasi, Katyayani, Franzen, Oscar, Koplev, Simon, Whatling, Carl, Belbin, Gillian M., Yang, Jialiang, Hao, Ke, Kenny, Eimear E., Tu, Zhidong, Zhu, Jun, Gan, Li-Ming, Do, Ron, Giannarelli, Chiara, Kovacic, Jason C., Ruusalepp, Arno, Lusis, Aldons J., Bjorkegren, Johan L. M., Schadt, Eric E.

Volltext

The landscape of human tissue and cell type specific expression and co-regulation of senescence genes von Xu, Peng, Wang, Minghui, Song, Won-Min, Wang, Qian, Yuan, Guo-Cheng, Sudmant, Peter H, Zare, Habil, Tu, Zhidong, Orr, Miranda E, Zhang, Bin

Volltext

Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation von Zhu, Jun, Sova, Pavel, Xu, Qiuwei, Dombek, Kenneth M, Xu, Ethan Y, Vu, Heather, Tu, Zhidong, Brem, Rachel B, Bumgarner, Roger E, Schadt, Eric E

Volltext

A comprehensive integrated post-GWAS analysis of Type 1 diabetes reveals enhancer-based immune dysregulation von Kim, Seung-Soo, Hudgins, Adam D, Yang, Jiping, Zhu, Yizhou, Tu, Zhidong, Rosenfeld, Michael G, DiLorenzo, Teresa P, Suh, Yousin

Volltext

Integrative analysis of DNA methylation and gene expression data identifies EPAS1 as a key regulator of COPD von Yoo, Seungyeul, Takikawa, Sachiko, Geraghty, Patrick, Argmann, Carmen, Campbell, Joshua, Lin, Luan, Huang, Tao, Tu, Zhidong, Foronjy, Robert F, Feronjy, Robert, Spira, Avrum, Schadt, Eric E, Powell, Charles A, Zhu, Jun

Volltext

Baf250a orchestrates an epigenetic pathway to repress the Nkx2.5-directed contractile cardiomyocyte program in the sinoatrial node von Wu, Meng, Peng, Siwu, Yang, Jialiang, Tu, Zhidong, Cai, Xiaoqiang, Cai, Chen-Leng, Wang, Zhong, Zhao, Yong

Volltext

Improved Human Age Prediction by Using Gene Expression Profiles From Multiple Tissues von Wang, Fayou, Yang, Jialiang, Lin, Huixin, Li, Qian, Ye, Zixuan, Lu, Qingqing, Chen, Luonan, Tu, Zhidong, Tian, Geng

Volltext

Multifaceted roles of miR-1s in repressing the fetal gene program in the heart von Wei, Yusheng, Peng, Siwu, Wu, Meng, Sachidanandam, Ravi, Tu, Zhidong, Zhang, Shihong, Falce, Christine, Sobie, Eric A, Lebeche, Djamel, Zhao, Yong

Volltext

A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila von Wang, Li, Tu, Zhidong, Sun, Fengzhu

Volltext

Transcriptomic Changes Highly Similar to Alzheimer's Disease Are Observed in a Subpopulation of Individuals During Normal Brain Aging von Peng, Shouneng, Zeng, Lu, Haure-Mirande, Jean-Vianney, Wang, Minghui, Huffman, Derek M, Haroutunian, Vahram, Ehrlich, Michelle E, Zhang, Bin, Tu, Zhidong

Volltext

Molecular differences in brain regional vulnerability to aging between males and females von Zhou, Xianxiao, Cao, Jiqing, Zhu, Li, Farrell, Kurt, Wang, Minghui, Guo, Lei, Yang, Jialiang, McKenzie, Andrew, Crary, John F, Cai, Dongming, Tu, Zhidong, Zhang, Bin

Volltext

Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence von Savić, Radoslav, Yang, Jialiang, Koplev, Simon, An, Mahru C., Patel, Priyanka L., O’Brien, Robert N., Dubose, Brittany N., Dodatko, Tetyana, Rogatsky, Eduard, Sukhavasi, Katyayani, Ermel, Raili, Ruusalepp, Arno, Houten, Sander M., Kovacic, Jason C., Stewart, Andrew F., Yohn, Christopher B., Schadt, Eric E., Laberge, Remi-Martin, Björkegren, Johan L.M., Tu, Zhidong, Argmann, Carmen

Volltext

Temporal genetic association and temporal genetic causality methods for dissecting complex networks von Lin, Luan, Chen, Quan, Hirsch, Jeanne P., Yoo, Seungyeul, Yeung, Kayee, Bumgarner, Roger E., Tu, Zhidong, Schadt, Eric E., Zhu, Jun

Volltext

A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells von Yang, Jialiang, Hagen, Jacob, Guntur, Kalyani V, Allette, Kimaada, Schuyler, Sarah, Ranjan, Jyoti, Petralia, Francesca, Gesta, Stephane, Sebra, Robert, Mahajan, Milind, Zhang, Bin, Zhu, Jun, Houten, Sander, Kasarskis, Andrew, Vishnudas, Vivek K, Akmaev, Viatcheslav R, Sarangarajan, Rangaprasad, Narain, Niven R, Schadt, Eric E, Argmann, Carmen A, Tu, Zhidong

Volltext

A Compendium of Age-Related PheWAS and GWAS Traits for Human Genetic Association Studies, Their Networks and Genetic Correlations von Kim, Seung-Soo, Hudgins, Adam D, Gonzalez, Brenda, Milman, Sofiya, Barzilai, Nir, Vijg, Jan, Tu, Zhidong, Suh, Yousin

Volltext

MODMatcher: multi-omics data matcher for integrative genomic analysis von Yoo, Seungyeul, Huang, Tao, Campbell, Joshua D, Lee, Eunjee, Tu, Zhidong, Geraci, Mark W, Powell, Charles A, Schadt, Eric E, Spira, Avrum, Zhu, Jun

Volltext

Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets von Tu, Zhidong, Keller, Mark P, Zhang, Chunsheng, Rabaglia, Mary E, Greenawalt, Danielle M, Yang, Xia, Wang, I-Ming, Dai, Hongyue, Bruss, Matthew D, Lum, Pek Y, Zhou, Yun-Ping, Kemp, Daniel M, Kendziorski, Christina, Yandell, Brian S, Attie, Alan D, Schadt, Eric E, Zhu, Jun

Volltext

Network Motif Identification in Stochastic Networks von Jiang, Rui, Tu, Zhidong, Chen, Ting, Sun, Fengzhu

Volltext