P1489: MANAGEMENT OF SICKLE CELL DISEASE WITH HYDROXYUREA: A SYSTEMATIC REVIEW FROM LOW‐ AND MIDDLE‐INCOME COUNTRIES von Paintsil, V., Marfo, K., Adisa, F., Khan, S., Tshilolo, L. M.

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Blood Transfusion Rate in Congolese Patients with Sickle Cell Anemia von TSHILOLO M, L, MUKENDI K, R, WEMBONYAMA O, S

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Resistance profiles of urinary Escherichia coli and Klebsiella pneumoniae isolates to antibiotics commonly prescribed for treatment of urinary tract infections at Monkole Hospital... von Mukubwa, G. K., Lukusa, F. N., Kavulikirwa, O. K., Liesse, J. I., Tshilolo, L. M., Memvanga, P. B.

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O‐01: HYDROXYUREA REDUCES THE TRANSFUSION BURDEN IN CHILDREN WITH SICKLE CELL ANEMIA IN SUB‐SAHARAN AFRICA: THE REACH EXPERIENCE von A., POWER‐HAYS, G., TOMLINSON, L., TSHILOLO, B., SANTOS, T., WILLIAMS, P., OLUPOT‐OLUPOT, L., SMART, P., MCGANN, S., STUBER, T., LATHAM, R., WARE

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P312: Blood safety: how to prevent contamination by HIV, Hepatitis B and C and Syphilis to blood donor in Lubumbashi von Wembonyama, O, Tshilolo, ML, Tshintshiompo, C, WC, Mpoy, MC, Watu

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P270: Reduce maternal deaths related to the maternity hospital acquired infections: impossible pari for the Democratic Republic of the Congo? von Wembonyama, O, Tshilolo, ML, Tshintshiompo, C, Mpoy, WC, Mutombo, KA, Watu, MC

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Artemisia Spp. Derivatives for COVID-19 Treatment: Anecdotal Use, Political Hype, Treatment Potential, Challenges, and Road Map to Randomized Clinical Trials von Kapepula, Paulin M, Kabengele, Jimmy K, Kingombe, Micheline, Van Bambeke, Françoise, Tulkens, Paul M, Sadiki Kishabongo, Antoine, Decloedt, Eric, Zumla, Adam, Tiberi, Simon, Suleman, Fatima, Tshilolo, Léon, Muyembe-TamFum, Jean-Jacques, Zumla, Alimuddin, Nachega, Jean B

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Estimating the number of probable new SARS-CoV-2 infections among tested subjects from the number of confirmed cases von Diarra, YM, Wimba, PM, Katchunga, PB, Bengehya, J, Miganda, B, Oyimangirwe, M, Tshilolo, L, Ahuka, SM, Iwaz, J, Étard, JF, Écochard, R, Vanhems, P, Rabilloud, M

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Neonatal screening for sickle cell anaemia in the Democratic Republic of the Congo: experience from a pioneer project on 31 204 newborns von Tshilolo, L, Aissi, L M, Lukusa, D, Kinsiama, C, Wembonyama, S, Gulbis, B, Vertongen, F

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Defining global strategies to improve outcomes in sickle cell disease: a Lancet Haematology Commission von Piel, Frédéric B, Rees, David C, DeBaun, Michael R, Nnodu, Obiageli, Ranque, Brigitte, Thompson, Alexis A, Ware, Russell E, Abboud, Miguel R, Abraham, Allistair, Ambrose, Emmanuela E, Andemariam, Biree, Colah, Roshan, Colombatti, Raffaella, Conran, Nicola, Costa, Fernando F, Cronin, Robert M, de Montalembert, Mariane, Elion, Jacques, Esrick, Erica, Greenway, Anthea L, Idris, Ibrahim M, Issom, David-Zacharie, Jain, Dipty, Jordan, Lori C, Kaplan, Zane S, King, Allison A, Lloyd-Puryear, Michele, Oppong, Samuel A, Sharma, Akshay, Sung, Lillian, Tshilolo, Leon, Wilkie, Diana J, Ohene-Frempong, Kwaku

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Neonatal screening and clinical care programmes for sickle cell disorders in sub-Saharan Africa: Lessons from pilot studies von Tshilolo, L, Kafando, E, Sawadogo, M, Cotton, F, Vertongen, F, Ferster, A, Gulbis, B

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Novel Genetic Loci That Influence Fetal Hemoglobin Expression in Children with Sickle Cell Anemia von Marahatta, Anu, Howard, Thad A., Stuber, Susan E., McElhinney, Kathryn L, Tshilolo, Leon, Williams, Thomas N., Olupot-Olupot, Peter, Santos, Brigida, John, Chandy C., Opoka, Robert, Nieves, Rosa M., Mena, Rafael, Baker, Jasmine, Latham, Teresa, Flanagan, Jonathan M., Ware, Russell E.

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P1481: THE INTERNATIONAL HEMOGLOBINOPATHY RESEARCH NETWORK (INHERENT): AN INTERNATIONAL INITIATIVE TO STUDY THE ROLE OF GENETIC MODIFIERS IN HEMOGLOBINOPATHIES von Kountouris, P., Stephanou, C., Archer, N., Bonifazi, F., Giannuzzi, V., Kuo, K., Maggio, A., Makani, J., Mañú Pereira, M. D. M., Michailidou, K., Nkya, S. W., Nnodu, O., Trompeter, S., Tshilolo, L., Wonkam, A., Zilfalil, B. A., Inusa, B., Kleanthous, M.

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PI‐07: THE INTERNATIONAL HEMOGLOBINOPATHY RESEARCH NETWORK (INHERENT): AN INTERNATIONAL INITIATVE TO STUDY THE ROLE OF GENETIC MODIFIERS IN HEMOGLOBINOPATHIES von P., KOUNTOURIS, C., STEPHANOU, N., ARCHER, F., BONIFAZI, V., GIANNUZZI, K., KUO, A., MAGGIO, J., MAKANI, M., MAÑÚ PEREIRA, K., MICHAILIDOU, S., NKYA, O., NNODU, S., TROMPETER, L., TSHILOLO, A., WONKAM, B., ZILFALIL, B., INUSA, M., KLEANTHOUS

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Genetic Variants That Influence Fetal Hemoglobin Expression from Hydroxyurea Treatment von Marahatta, Anu, Flanagan, Jonathan M., Howard, Thad A., Mortier, Nicole, Schultz, William, McElhinney, Kathryn L, Tshilolo, Leon, Williams, Thomas N., Olupot-Olupot, Peter, Santos, Brigida, John, Chandy C., Opoka, Robert, Nieves, Rosa M., Mena, Rafael, Reid, Marvin E, Rankine-Mullings, Angela, Baker, Jasmine, McGann, Patrick T., Aygun, Banu, Lane, Adam, Tomlinson, George A., Latham, Teresa, Stuber, Susan E., Ware, Russell E.

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P117: THE INTERNATIONAL HAEMOGLOBINOPATHY RESEARCH NETWORK (INHERENT): AN INTERNATIONAL INITIATIVE TO STUDY THE ROLE OF GENETIC MODIFIERS IN HAEMOGLOBINOPATHIES von Kountouris, P, Stephanou, C, Archer, N, Bonifazi, F, Giannuzzi, V, Kuo, K, Maggio, A, Makani, J, Mañú Pereira, M, Michailidou, K, Nkya, S, Nnodu, O, Trompeter, S, Tshilolo, L, Wonkam, A, Zilfalil, B, Inusa, B, Kleanthous, M

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Population Pharmacokinetics of the Antimalarial Amodiaquine: a Pooled Analysis To Optimize Dosing von Ali, Ali Mohamed, Penny, Melissa A, Smith, Thomas A, Workman, Lesley, Sasi, Philip, Adjei, George O, Aweeka, Francesca, Kiechel, Jean-René, Jullien, Vincent, Rijken, Marcus J, McGready, Rose, Mwesigwa, Julia, Kristensen, Kim, Stepniewska, Kasia, Tarning, Joel, Barnes, Karen I, Denti, Paolo

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P135: THE CLINGEN HEMOGLOBINOPATHY VARIANT CURATION EXPERT PANEL von Coralea Stephanou, C, Petros Kountouris, P, Carsten W Lederer, C, Celeste Bento, C, Cornelis L Hartveld, C, Jan Traeger‐Synodinos, J, John S Waye, J, Zhiyu Peng, Z, Irene Fylaktou, I, Hashim Halim‐Fikri, H, Tamara T. Koopmann, T, Landry Nfonsam, L, Jun Sun, J, Franck Nzengu‐Lukusa, F, Michael Angastiniotis, M, Catherine Badens, C, Bertha Ibarra Cortes, B, Johan T. den Dunnen, J, Jacques Elion, J, Suthat Fucharoen, S, Kyriaki Michailidou, K, Thessalia Papasavva, T, Antonio Piga, A, Raj Ramesar, R, Swee Lay Thein, S, Léon Tshilolo, L, Zilfalil Bin Alwi, Z, Marina Kleanthous, M

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Newborn screening for sickle cell disease in Europe: recommendations from a Pan‐European Consensus Conference von Lobitz, S, Telfer, P, Cela, E, Allaf, B, Angastiniotis, M, Backman Johansson, C, Badens, C, Bento, C, Bouva, MJ, Canatan, D, Charlton, M, Coppinger, C, Daniel, Y, De Montalembert, M, Ducoroy, P, Dulin, E, Fingerhut, R, Frömmel, C, García-Morin, M, Gulbis, B, Holtkamp, U, Inusa, B, James, J, Kleanthous, M, Klein, J, Kunz, JB, Langabeer, L, Lapouméroulie, C, Marcao, A, Marín Soria, JL, McMahon, C, Ohene-Frempong, K, Périni, J-M, Piel, FB, Russo, G, Sainati, L, Schmugge, M, Streetly, A, Tshilolo, L, Turner, C, Venturelli, D, Vilarinho, L, Yahyaoui, R, Elion, J, Colombatti, R, With the endorsement of EuroBloodNet, the European Reference Network in Rare Haematological Diseases

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Defining global strategies to improve outcomes in sickle cell disease: a Lancet Haematology commission von Piel, F, Rees, DC, BeBaun, MR, Nnodu, MR, Ranque, B, Thompson, AA, Ware, RE, Abboud, MR, Abraham, A, Ambrose, EE, Andemariam, B, Colah, R, Colombatti, R, Conran, N, Costa, FF, Cronin, RM, De Montalembert, M, Elion, J, Esrick, E, Greenway, AL, Idris, I, Issom, DZ, Jain, D, Jordan, LC, Kaplan, ZS, King, AA, Lloyd-Puryear, M, Oppong, SA, Sharma, A, Sung, L, Tshilolo, L, Wilkie, DJ, Ohene-Frempong, K

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