Sequential adaptive mutations enhance efficient vector switching by Chikungunya virus and its epidemic emergence von Tsetsarkin, Konstantin A, Weaver, Scott C

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A single mutation in chikungunya virus affects vector specificity and epidemic potential von Tsetsarkin, Konstantin A, Vanlandingham, Dana L, McGee, Charles E, Higgs, Stephen

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Epistatic Roles of E2 Glycoprotein Mutations in Adaption of Chikungunya Virus to Aedes Albopictus and Ae. Aegypti Mosquitoes von Tsetsarkin, Konstantin A, McGee, Charles E, Volk, Sara M, Vanlandingham, Dana L, Weaver, Scott C, Higgs, Stephen

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A Full-Length Infectious cDNA Clone of Zika Virus from the 2015 Epidemic in Brazil as a Genetic Platform for Studies of Virus-Host Interactions and Vaccine Development von Tsetsarkin, Konstantin A, Kenney, Heather, Chen, Rubing, Liu, Guangping, Manukyan, Hasmik, Whitehead, Stephen S, Laassri, Majid, Chumakov, Konstantin, Pletnev, Alexander G

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Chikungunya virus emergence is constrained in Asia by lineage-specific adaptive landscapes von Tsetsarkin, Konstantin A, Chen, Rubing, Leal, Grace, Forrester, Naomi, Higgs, Stephen, Huang, Jing, Weaver, Scott C

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Zika virus tropism during early infection of the testicular interstitium and its role in viral pathogenesis in the testes von Tsetsarkin, Konstantin A, Acklin, Joshua A, Liu, Guangping, Kenney, Heather, Teterina, Natalia L, Pletnev, Alexander G, Lim, Jean K

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Chikungunya virus 3' untranslated region: adaptation to mosquitoes and a population bottleneck as major evolutionary forces von Chen, Rubing, Wang, Eryu, Tsetsarkin, Konstantin A, Weaver, Scott C

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Genome-Scale Phylogenetic Analyses of Chikungunya Virus Reveal Independent Emergences of Recent Epidemics and Various Evolutionary Rates von Volk, Sara M, Chen, Rubing, Tsetsarkin, Konstantin A, Adams, A Paige, Garcia, Tzintzuni I, Sall, Amadou A, Nasar, Farooq, Schuh, Amy J, Holmes, Edward C, Higgs, Stephen, Maharaj, Payal D, Brault, Aaron C, Weaver, Scott C

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Epididymal epithelium propels early sexual transmission of Zika virus in the absence of interferon signaling von Pletnev, Alexander G., Maximova, Olga A., Liu, Guangping, Kenney, Heather, Nagata, Bianca M., Zagorodnyaya, Tatiana, Moore, Ian, Chumakov, Konstantin, Tsetsarkin, Konstantin A.

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Genomic and phenotypic analyses suggest moderate fitness differences among Zika virus lineages von Oliveira, Glenn, Vogels, Chantal B F, Zolfaghari, Ashley, Saraf, Sharada, Klitting, Raphaelle, Weger-Lucarelli, James, P Leon, Karla, Ontiveros, Carlos O, Agarwal, Rimjhim, Tsetsarkin, Konstantin A, Harris, Eva, Ebel, Gregory D, Wohl, Shirlee, Grubaugh, Nathan D, Andersen, Kristian G

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The Roles of prM-E Proteins in Historical and Epidemic Zika Virus-mediated Infection and Neurocytotoxicity von Li, Ge, Bos, Sandra, Tsetsarkin, Konstantin A, Pletnev, Alexander G, Desprès, Philippe, Gadea, Gilles, Zhao, Richard Y

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Routes of Zika virus dissemination in the testis and epididymis of immunodeficient mice von Tsetsarkin, Konstantin A., Maximova, Olga A., Liu, Guangping, Kenney, Heather, Teterina, Natalia, Bloom, Marshall E., Grabowski, Jeffrey M., Mlera, Luwanika, Nagata, Bianca M., Moore, Ian, Martens, Craig, Amaro-Carambot, Emerito, Lamirande, Elaine W., Whitehead, Stephen S., Pletnev, Alexander G.

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Novel Approach for Insertion of Heterologous Sequences into Full-Length ZIKV Genome Results in Superior Level of Gene Expression and Insert Stability von Volkova, Evgeniya, Tsetsarkin, Konstantin A, Sippert, Emilia, Assis, Felipe, Liu, Guangping, Rios, Maria, Pletnev, Alexander G

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Dual miRNA targeting restricts host range and attenuates neurovirulence of flaviviruses von Tsetsarkin, Konstantin A, Liu, Guangping, Kenney, Heather, Bustos-Arriaga, Jose, Hanson, Christopher T, Whitehead, Stephen S, Pletnev, Alexander G

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Synergistic Internal Ribosome Entry Site/MicroRNA-Based Approach for Flavivirus Attenuation and Live Vaccine Development von Tsetsarkin, Konstantin A, Liu, Guangping, Volkova, Evgeniya, Pletnev, Alexander G

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Stable and Highly Immunogenic MicroRNA-Targeted Single-Dose Live Attenuated Vaccine Candidate against Tick-Borne Encephalitis Constructed Using Genetic Backbone of Langat Virus von Tsetsarkin, Konstantin A, Maximova, Olga A, Liu, Guangping, Kenney, Heather, Teterina, Natalya L, Pletnev, Alexander G

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Chikungunya virus adaptation to Aedes albopictus mosquitoes does not correlate with acquisition of cholesterol dependence or decreased pH threshold for fusion reaction von Tsetsarkin, Konstantin A, McGee, Charles E, Higgs, Stephen

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Interspecies transmission and chikungunya virus emergence von Tsetsarkin, Konstantin A, Chen, Rubing, Weaver, Scott C

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Stability of yellow fever virus under recombinatory pressure as compared with chikungunya virus von McGee, Charles E, Tsetsarkin, Konstantin A, Guy, Bruno, Lang, Jean, Plante, Kenneth, Vanlandingham, Dana L, Higgs, Stephen

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Multi-peaked adaptive landscape for chikungunya virus evolution predicts continued fitness optimization in Aedes albopictus mosquitoes von Tsetsarkin, Konstantin A., Chen, Rubing, Yun, Ruimei, Rossi, Shannan L., Plante, Kenneth S., Guerbois, Mathilde, Forrester, Naomi, Perng, Guey Chuen, Sreekumar, Easwaran, Leal, Grace, Huang, Jing, Mukhopadhyay, Suchetana, Weaver, Scott C.

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