ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor von Tse, Christin, Shoemaker, Alexander R, Adickes, Jessica, Anderson, Mark G, Chen, Jun, Jin, Sha, Johnson, Eric F, Marsh, Kennan C, Mitten, Michael J, Nimmer, Paul, Roberts, Lisa, Tahir, Stephen K, Xiao, Yu, Yang, Xiufen, Zhang, Haichao, Fesik, Stephen, Rosenberg, Saul H, Elmore, Steven W

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Discovery of an Orally Bioavailable Small Molecule Inhibitor of Prosurvival B-Cell Lymphoma 2 Proteins von Park, Cheol-Min, Bruncko, Milan, Adickes, Jessica, Bauch, Joy, Ding, Hong, Kunzer, Aaron, Marsh, Kennan C, Nimmer, Paul, Shoemaker, Alexander R, Song, Xiaohong, Tahir, Stephen K, Tse, Christin, Wang, Xilu, Wendt, Michael D, Yang, Xiufen, Zhang, Haichao, Fesik, Stephen W, Rosenberg, Saul H, Elmore, Steven W

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Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737 von TAHIR, Stephen K, XIUFEN YANG, ROSENBERG, Saul H, TSE, Christin, ANDERSON, Mark G, MORGAN-LAPPE, Susan E, SARTHY, Aparna V, JUN CHEN, WARNER, Robert B, NG, Shi-Chung, FESIK, Stephen W, ELMORE, Steve W

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Activity of the Bcl-2 Family Inhibitor ABT-263 in a Panel of Small Cell Lung Cancer Xenograft Models von SHOEMAKER, Alex R, MITTEN, Michael J, BAUCH, Joy, MARSH, Kennan, TAHIR, Steven K, XIUFENYANG, TSE, Christin, FESIK, Stephen W, ROSENBERG, Saul H, ELMORE, Steven W, ADICKES, Jessica, ACKLER, Scott, REFICI, Marion, FERGUSON, Debra, OLEKSIJEW, Anatol, O'CONNOR, Jacqueline M, BAOLE WANG, FROST, David J

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The Bcl-2 inhibitor ABT-263 enhances the response of multiple chemotherapeutic regimens in hematologic tumors in vivo von Ackler, Scott, Mitten, Michael J., Foster, Kelly, Oleksijew, Anatol, Refici, Marion, Tahir, Stephen K., Xiao, Yu, Tse, Christin, Frost, David J., Fesik, Stephen W., Rosenberg, Saul H., Elmore, Steven W., Shoemaker, Alexander R.

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Disruption of Higher-Order Folding by Core Histone Acetylation Dramatically Enhances Transcription of Nucleosomal Arrays by RNA Polymerase III von Tse, Christin, Sera, Takashi, Wolffe, Alan P., Hansen, Jeffrey C.

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ABT-263 and rapamycin act cooperatively to kill lymphoma cells in vitro and in vivo von Ackler, Scott, Xiao, Yu, Mitten, Michael J, Foster, Kelly, Oleksijew, Anatol, Refici, Marion, Schlessinger, Sally, Wang, Baole, Chemburkar, Sanjay R, Bauch, Joy, Tse, Christin, Frost, David J, Fesik, Stephen W, Rosenberg, Saul H, Elmore, Steven W, Shoemaker, Alex R

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Structure and Function of the Core Histone N-Termini:  More Than Meets the Eye von Hansen, Jeffrey C, Tse, Christin, Wolffe, Alan P

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Hybrid Trypsinized Nucleosomal Arrays:  Identification of Multiple Functional Roles of the H2A/H2B and H3/H4 N-Termini in Chromatin Fiber Compaction von Tse, Christin, Hansen, Jeffrey C

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Predicting protein druggability von Hajduk, Philip J., Huth, Jeffrey R., Tse, Christin

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The Yeast Histone Acetyltransferase A2 Complex, but Not Free Gcn5p, Binds Stably to Nucleosomal Arrays von Sendra, Ramon, Tse, Christin, Hansen, Jeffrey C.

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Assembly of defined nucleosomal and chromatin arrays from pure components von Carruthers, Lenny M., Tse, Christin, Walker, Kerfoot P., Hansen, Jeffrey C.

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Enhanced Transcription Factor Access to Arrays of Histone H3/H4 Tetramer· DNA Complexes in vitro: Implications for Replication and Transcription von Tse, Christin, Fletcher, Terace M., Hansen, Jeffrey C.

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Gcn5p, a Transcription-related Histone Acetyltransferase, Acetylates Nucleosomes and Folded Nucleosomal Arrays in the Absence of Other Protein Subunits von Georgieva, Elena I., Ruiz-Garcı́a, Ana B., Sendra, Ramon, Hansen, Jeffrey C., Tse, Christin

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Identification of expression signatures predictive of sensitivity to the Bcl-2 family member inhibitor ABT-263 in small cell lung carcinoma and leukemia/lymphoma cell lines von Tahir, Stephen K, Wass, John, Joseph, Mary K, Devanarayan, Viswanath, Hessler, Paul, Zhang, Haichao, Elmore, Steve W, Kroeger, Paul E, Tse, Christin, Rosenberg, Saul H, Anderson, Mark G

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Human Semaphorin 3B (SEMA3B) located at chromosome 3p21.3 suppresses tumor formation in an adenocarcinoma cell line von TSE, Christin, XIANG, Ruinua H, BRACHT, Todd, NAYLOR, Susan L

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N-Aryl-benzimidazolones as novel small molecule HSP90 inhibitors von Bruncko, Milan, Tahir, Stephen K., Song, Xiaohong, Chen, Jun, Ding, Hong, Huth, Jeffrey R., Jin, Sha, Judge, Russell A., Madar, David J., Park, Chang H., Park, Cheol-Min, Petros, Andrew M., Tse, Christin, Rosenberg, Saul H., Elmore, Steven W.

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Semaphorin 3F gene from human 3p21.3 suppresses tumor formation in nude mice von RUIHUA XIANG, DAVALOS, Albert R, HENSEL, Charles H, ZHOU, Xiao-Jun, TSE, Christin, NAYLOR, Susan L

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The Core Histone N-Terminal Domains Are Required for Multiple Rounds of Catalytic Chromatin Remodeling by the SWI/SNF and RSC Complexes von Logie, Colin, Tse, Christin, Hansen, Jeffrey C, Peterson, Craig L

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The Bcl-2 Family Inhibitor ABT-263 Shows Significant but Reversible Thrombocytopenia in Mice von Shoemaker, Alex R., Mitten, Michael J., Adickes, Jessica, Oleksijew, Anatol, Zhang, Haichao, Bauch, Joy, Marsh, Kennan, Frost, David J., Madar, David, Tse, Christin, Fesik, Stephen W., Rosenberg, Saul H., Elmore, Steven W.

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