Perspective: Designing T-Cell Engagers With Better Therapeutic Windows von Vafa, Omid, Trinklein, Nathan D

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Anti-BCMA chimeric antigen receptors with fully human heavy-chain-only antigen recognition domains von Lam, Norris, Trinklein, Nathan D., Buelow, Benjamin, Patterson, George H., Ojha, Namrata, Kochenderfer, James N.

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Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue von Innocenti, Federico, Cooper, Gregory M, Stanaway, Ian B, Gamazon, Eric R, Smith, Joshua D, Mirkov, Snezana, Ramirez, Jacqueline, Liu, Wanqing, Lin, Yvonne S, Moloney, Cliona, Aldred, Shelly Force, Trinklein, Nathan D, Schuetz, Erin, Nickerson, Deborah A, Thummel, Ken E, Rieder, Mark J, Rettie, Allan E, Ratain, Mark J, Cox, Nancy J, Brown, Christopher D

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A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo expansion of CD8 and NK cells von Harris, Katherine E., Lorentsen, Kyle J., Malik-Chaudhry, Harbani K., Loughlin, Kaitlyn, Basappa, Harish Medlari, Hartstein, Sharon, Ahmil, Ghenima, Allen, Nicole S., Avanzino, Brian C., Balasubramani, Aarti, Boudreau, Andrew A., Chang, Karen, Cuturi, Maria-Cristina, Davison, Laura M., Ho, Dennis M., Iyer, Suhasini, Rangaswamy, Udaya S., Sankaran, Preethi, Schellenberger, Ute, Buelow, Roland, Trinklein, Nathan D.

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An abundance of bidirectional promoters in the human genome von Trinklein, Nathan D, Aldred, Shelley Force, Hartman, Sara J, Schroeder, Diane I, Otillar, Robert P, Myers, Richard M

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Author Correction: Anti-BCMA chimeric antigen receptors with fully human heavy-chain-only antigen recognition domains von Lam, Norris, Trinklein, Nathan D., Buelow, Benjamin, Patterson, George H., Ojha, Namrata, Kochenderfer, James N.

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Genome-wide discovery of drug-dependent human liver regulatory elements von Smith, Robin P, Eckalbar, Walter L, Morrissey, Kari M, Luizon, Marcelo R, Hoffmann, Thomas J, Sun, Xuefeng, Jones, Stacy L, Force Aldred, Shelley, Ramamoorthy, Anuradha, Desta, Zeruesenay, Liu, Yunlong, Skaar, Todd C, Trinklein, Nathan D, Giacomini, Kathleen M, Ahituv, Nadav

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Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies von Trinklein, Nathan D, Pham, Duy, Schellenberger, Ute, Buelow, Ben, Boudreau, Andrew, Choudhry, Priya, Clarke, Starlynn C, Dang, Kevin, Harris, Katherine E, Iyer, Suhasini, Jorgensen, Brett, Pratap, Payal P, Rangaswamy, Udaya S, Ugamraj, Harshad S, Vafa, Omid, Wiita, Arun P, van Schooten, Wim, Buelow, Roland, Force Aldred, Shelley

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Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome von Cooper, Sara J, Trinklein, Nathan D, Anton, Elizabeth D, Nguyen, Loan, Myers, Richard M

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Functional analysis of transcription factor binding sites in human promoters von Whitfield, Troy W, Wang, Jie, Collins, Patrick J, Partridge, E Christopher, Aldred, Shelley Force, Trinklein, Nathan D, Myers, Richard M, Weng, Zhiping

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The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response von Trinklein, Nathan D, Murray, John I, Hartman, Sara J, Botstein, David, Myers, Richard M

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When monoclonal antibodies are not monospecific: Hybridomas frequently express additional functional variable regions von Bradbury, Andrew R M, Trinklein, Nathan D, Thie, Holger, Wilkinson, Ian C, Tandon, Atul K, Anderson, Stephen, Bladen, Catherine L, Jones, Brittany, Aldred, Shelley Force, Bestagno, Marco, Burrone, Oscar, Maynard, Jennifer, Ferrara, Fortunato, Trimmer, James S, Görnemann, Janina, Glanville, Jacob, Wolf, Philipp, Frenzel, Andre, Wong, Julin, Koh, Xin Yu, Eng, Hui-Yan, Lane, David, Lefranc, Marie-Paule, Clark, Mike, Dübel, Stefan

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Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release von Dang, Kevin, Castello, Giulia, Clarke, Starlynn C, Li, Yuping, Balasubramani, Aarti, Boudreau, Andrew, Davison, Laura, Harris, Katherine E, Pham, Duy, Sankaran, Preethi, Ugamraj, Harshad S, Deng, Rong, Kwek, Serena, Starzinski, Alec, Iyer, Suhasini, van Schooten, Wim, Schellenberger, Ute, Sun, Wenchao, Trinklein, Nathan D, Buelow, Roland, Buelow, Ben, Fong, Lawrence, Dalvi, Pranjali

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TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL von Malik-Chaudhry, Harbani K, Prabhakar, Kirthana, Ugamraj, Harshad S, Boudreau, Andrew A, Buelow, Benjamin, Dang, Kevin, Davison, Laura M, Harris, Katherine E, Jorgensen, Brett, Ogana, Heather, Pham, Duy, Schellenberger, Ute, Van Schooten, Wim, Buelow, Roland, Iyer, Suhasini, Trinklein, Nathan D, Rangaswamy, Udaya S

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Diverse and specific gene expression responses to stresses in cultured human cells von Murray, John Isaac, Whitfield, Michael L, Trinklein, Nathan D, Myers, Richard M, Brown, Patrick O, Botstein, David

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Transcription factor binding and modified histones in human bidirectional promoters von Lin, Jane M, Collins, Patrick J, Trinklein, Nathan D, Fu, Yutao, Xi, Hualin, Myers, Richard M, Weng, Zhiping

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Sequence features that drive human promoter function and tissue specificity von Landolin, Jane M, Johnson, David S, Trinklein, Nathan D, Aldred, Shelly F, Medina, Catherine, Shulha, Hennady, Weng, Zhiping, Myers, Richard M

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Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies von Harris, Katherine E, Aldred, Shelley Force, Davison, Laura M, Ogana, Heather Anne N, Boudreau, Andrew, Brüggemann, Marianne, Osborn, Michael, Ma, Biao, Buelow, Benjamin, Clarke, Starlynn C, Dang, Kevin H, Iyer, Suhasini, Jorgensen, Brett, Pham, Duy T, Pratap, Payal P, Rangaswamy, Udaya S, Schellenberger, Ute, van Schooten, Wim C, Ugamraj, Harshad S, Vafa, Omid, Buelow, Roland, Trinklein, Nathan D

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A Single Human Papillomavirus Vaccine Dose Improves B Cell Memory in Previously Infected Subjects von Scherer, Erin M., Smith, Robin A., Gallego, Daniel F., Carter, Joseph J., Wipf, Gregory C., Hoyos, Manuela, Stern, Michael, Thurston, Tate, Trinklein, Nathan D., Wald, Anna, Galloway, Denise A.

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Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies von Clarke, Starlynn C, Ma, Biao, Trinklein, Nathan D, Schellenberger, Ute, Osborn, Michael J, Ouisse, Laure-Hélène, Boudreau, Andrew, Davison, Laura M, Harris, Katherine E, Ugamraj, Harshad S, Balasubramani, Aarti, Dang, Kevin H, Jorgensen, Brett, Ogana, Heather Anne N, Pham, Duy T, Pratap, Payal P, Sankaran, Preethi, Anegon, Ignacio, van Schooten, Wim C, Brüggemann, Marianne, Buelow, Roland, Force Aldred, Shelley

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