Lack of an association between clinical INSTI-related body weight gain and direct interference with MC4 receptor (MC4R), a key central regulator of body weight von McMahon, Carrie, Trevaskis, James L, Carter, Christoph, Holsapple, Kevin, White, Kirsten, Das, Moupali, Collins, Sean, Martin, Hal, Burns-Naas, Leigh Ann

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Glucagon-like peptide-1 receptor agonism improves metabolic, biochemical, and histopathological indices of nonalcoholic steatohepatitis in mice von Trevaskis, James L, Griffin, Peter S, Wittmer, Carrie, Neuschwander-Tetri, Brent A, Brunt, Elizabeth M, Dolman, Carrie S, Erickson, Mary R, Napora, James, Parkes, David G, Roth, Jonathan D

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Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source von Boland, Michelle L, Oró, Denise, Tølbøl, Kirstine S, Thrane, Sebastian T, Nielsen, Jens Christian, Cohen, Taylor S, Tabor, David E, Fernandes, Fiona, Tovchigrechko, Andrey, Veidal, Sanne S, Warrener, Paul, Sellman, Bret R, Jelsing, Jacob, Feigh, Michael, Vrang, Niels, Trevaskis, James L, Hansen, Henrik H

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Resolution of NASH and hepatic fibrosis by the GLP-1R and GCGR dual-agonist cotadutide via modulating mitochondrial function and lipogenesis von Boland, Michelle L., Laker, Rhianna C., Mather, Karly, Nawrocki, Arkadiusz, Oldham, Stephanie, Boland, Brandon B., Lewis, Hilary, Conway, James, Naylor, Jacqueline, Guionaud, Silvia, Feigh, Michael, Veidal, Sanne S., Lantier, Louise, McGuinness, Owen P., Grimsby, Joseph, Rondinone, Cristina M., Jermutus, Lutz, Larsen, Martin R., Trevaskis, James L., Rhodes, Christopher J.

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Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding von Cheng, Wenwen, Gonzalez, Ian, Pan, Warren, Tsang, Anthony H., Adams, Jessica, Ndoka, Ermelinda, Gordian, Desiree, Khoury, Basma, Roelofs, Karen, Evers, Simon S., MacKinnon, Andrew, Wu, Shuangcheng, Frikke-Schmidt, Henriette, Flak, Jonathan N., Trevaskis, James L., Rhodes, Christopher J., Fukada, So-ichiro, Seeley, Randy J., Sandoval, Darleen A., Olson, David P., Blouet, Clemence, Myers, Martin G.

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Targeting lipid biosynthesis pathways for hepatitis B virus cure von Hyrina, Anastasia, Burdette, Dara, Song, Zhijuan, Ramirez, Ricardo, Okesli-Armlovich, Ayse, Vijayakumar, Archana, Bates, Jamie, Trevaskis, James L, Fletcher, Simon P, Lee, William A, Holdorf, Meghan M

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Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies von Roth, Jonathan D, Roland, Barbara L, Cole, Rebecca L, Trevaskis, James L, Weyer, Christian, Koda, Joy E, Anderson, Christen M, Parkes, David G, Baron, Alain D

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Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis von Hansen, Henrik H, Ægidius, Helene M, Oró, Denise, Evers, Simon S, Heebøll, Sara, Eriksen, Peter Lykke, Thomsen, Karen Louise, Bengtsson, Anja, Veidal, Sanne S, Feigh, Michel, Suppli, Malte P, Knop, Filip K, Grønbæk, Henning, Miranda, Diego, Trevaskis, James L, Vrang, Niels, Jelsing, Jacob, Rigbolt, Kristoffer T G

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Nonalcoholic steatohepatitis severity is defined by a failure in compensatory antioxidant capacity in the setting of mitochondrial dysfunction von Boland, Michelle L, Oldham, Stephanie, Boland, Brandon B, Will, Sarah, Lapointe, Jean-Martin, Guionaud, Silvia, Rhodes, Christopher J, Trevaskis, James L

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Mechanisms of Amylin/Leptin Synergy in Rodent Models von Turek, Victoria F, Trevaskis, James L, Levin, Barry E, Dunn-Meynell, Ambrose A, Irani, Boman, Gu, Guibao, Wittmer, Carrie, Griffin, Peter S, Vu, Calvin, Parkes, David G, Roth, Jonathan D

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Superior reductions in hepatic steatosis and fibrosis with co-administration of a glucagon-like peptide-1 receptor agonist and obeticholic acid in mice von Jouihan, Hani, Will, Sarah, Guionaud, Silvia, Boland, Michelle L., Oldham, Stephanie, Ravn, Peter, Celeste, Anthony, Trevaskis, James L.

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Amylin-Mediated Restoration of Leptin Responsiveness in Diet-Induced Obesity: Magnitude and Mechanisms von Trevaskis, James L, Coffey, Todd, Cole, Rebecca, Lei, Chunli, Wittmer, Carrie, Walsh, Brandon, Weyer, Christian, Koda, Joy, Baron, Alain D, Parkes, David G, Roth, Jonathan D

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Rapid development of non-alcoholic steatohepatitis in Psammomys obesus (Israeli sand rat) von Spolding, Briana, Connor, Timothy, Wittmer, Carrie, Abreu, Lelia L F, Kaspi, Antony, Ziemann, Mark, Kaur, Gunveen, Cooper, Adrian, Morrison, Shona, Lee, Scott, Sinclair, Andrew, Gibert, Yann, Trevaskis, James L, Roth, Jonathon D, El-Osta, Assam, Standish, Richard, Walder, Ken

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Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergisti... von Boland, Brandon B., Laker, Rhianna C., O'Brien, Siobhan, Sitaula, Sadichha, Sermadiras, Isabelle, Nielsen, Jens Christian, Barkholt, Pernille, Roostalu, Urmas, Hecksher-Sørensen, Jacob, Sejthen, Sara Rubek, Thorbek, Ditte Dencker, Suckow, Arthur, Burmeister, Nicole, Oldham, Stephanie, Will, Sarah, Howard, Victor G., Gill, Benji M., Newton, Philip, Naylor, Jacqueline, Hornigold, David C., Austin, Jotham, Lantier, Louise, McGuinness, Owen P., Trevaskis, James L., Grimsby, Joseph S., Rhodes, Christopher J.

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Combined loss of GLP-1R and Y2R does not alter progression of high-fat diet-induced obesity or response to RYGB surgery in mice von Boland, Brandon B., Mumphrey, Michael B., Hao, Zheng, Townsend, R. Leigh, Gill, Benji, Oldham, Stephanie, Will, Sarah, Morrison, Christopher D., Yu, Sangho, Münzberg, Heike, Rhodes, Christopher J., Trevaskis, James L., Berthoud, Hans-Rudolf

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Melanocortin signaling in the CNS directly regulates circulating cholesterol von Perez-Tilve, Diego, Hofmann, Susanna M, Basford, Joshua, Nogueiras, Ruben, Pfluger, Paul T, Patterson, James T, Grant, Erin, Wilson-Perez, Hilary E, Granholm, Norman A, Arnold, Myrtha, Trevaskis, James L, Butler, Andrew A, Davidson, William S, Woods, Stephen C, Benoit, Stephen C, Sleeman, Mark W, DiMarchi, Richard D, Hui, David Y, Tschöp, Matthias H

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Combinations of an acetyl CoA carboxylase inhibitor with hepatic lipid modulating agents do not augment antifibrotic efficacy in preclinical models of NASH and fibrosis von Vijayakumar, Archana, Okesli‐Armlovich, Ayse, Wang, Ting, Olson, Isabel, Seung, Minji, Kusam, Saritha, Hollenback, David, Mahadevan, Sangeetha, Marchand, Bruno, Toteva, Maria, Breckenridge, David G., Trevaskis, James L., Bates, Jamie

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Improved glucose control and reduced body weight in rodents with dual mechanism of action peptide hybrids von Trevaskis, James L, Mack, Christine M, Sun, Chengzao, Soares, Christopher J, D'Souza, Lawrence J, Levy, Odile E, Lewis, Diane Y, Jodka, Carolyn M, Tatarkiewicz, Krystyna, Gedulin, Bronislava, Gupta, Swati, Wittmer, Carrie, Hanley, Michael, Forood, Bruce, Parkes, David G, Ghosh, Soumitra S

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Diet-Genotype Interactions in the Development of the Obese, Insulin-Resistant Phenotype of C57BL/6J Mice Lacking Melanocortin-3 or -4 Receptors von Sutton, Gregory M, Trevaskis, James L, Hulver, Matthew W, McMillan, Ryan P, Markward, Nathan J, Babin, M. Josephine, Meyer, Emily A, Butler, Andrew A

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A GLP-1:CCK fusion peptide harnesses the synergistic effects on metabolism of CCK-1 and GLP-1 receptor agonism in mice von Hornigold, David C., Roth, Emma, Howard, Victor, Will, Sarah, Oldham, Stephanie, Coghlan, Matthew P., Blouet, Clemence, Trevaskis, James L.

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