The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer von Soldi, Raffaella, Halder, Tithi Ghosh, Weston, Alexis, Thode, Trason, Drenner, Kevin, Lewis, Rhonda, Kaadige, Mohan R., Srivastava, Shreyesi, Ampanattu, Sherin Daniel, del Villar, Ryan Rodriguez, Lang, Jessica, Vankayalapati, Hariprasad, Weissman, Bernard, Trent, Jeffrey M., Hendricks, William P. D., Sharma, Sunil

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Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis von Hendricks, William P D, Zismann, Victoria, Sivaprakasam, Karthigayini, Legendre, Christophe, Poorman, Kelsey, Tembe, Waibhav, Perdigones, Nieves, Kiefer, Jeffrey, Liang, Winnie, DeLuca, Valerie, Stark, Mitchell, Ruhe, Alison, Froman, Roe, Duesbery, Nicholas S, Washington, Megan, Aldrich, Jessica, Neff, Mark W, Huentelman, Matthew J, Hayward, Nicholas, Brown, Kevin, Thamm, Douglas, Post, Gerald, Khanna, Chand, Davis, Barbara, Breen, Matthew, Sekulic, Alexander, Trent, Jeffrey M

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Small-Cell Carcinoma of the Ovary, Hypercalcemic Type-Genetics, New Treatment Targets, and Current Management Guidelines von Tischkowitz, Marc, Huang, Sidong, Banerjee, Susana, Hague, Jennifer, Hendricks, William P. D., Huntsman, David G., Lang, Jessica D., Orlando, Krystal A., Oza, Amit M., Pautier, Patricia, Ray-Coquard, Isabelle, Trent, Jeffrey M., Witcher, Michael, Witkowski, Leora, McCluggage, W. Glenn, Levine, Douglas A., Foulkes, William D., Weissman, Bernard E.

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Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients von Wong, Shukmei, Ehrhart, E. J, Stewart, Samuel, Zismann, Victoria, Cawley, Jacob, Halperin, Rebecca, Briones, Natalia, Richter, Keith, Sivaprakasam, Karthigayini, Perdigones, Nieves, Contente-Cuomo, Tania, Facista, Salvatore, Trent, Jeffrey M, Murtaza, Muhammed, Khanna, Chand, Hendricks, William P. D

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Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4 von Ramos, Pilar, Karnezis, Anthony N, Craig, David W, Sekulic, Aleksandar, Russell, Megan L, Hendricks, William P D, Corneveaux, Jason J, Barrett, Michael T, Shumansky, Karey, Yang, Yidong, Shah, Sohrab P, Prentice, Leah M, Marra, Marco A, Kiefer, Jeffrey, Zismann, Victoria L, McEachron, Troy A, Salhia, Bodour, Prat, Jaime, D'Angelo, Emanuela, Clarke, Blaise A, Pressey, Joseph G, Farley, John H, Anthony, Stephen P, Roden, Richard B S, Cunliffe, Heather E, Huntsman, David G, Trent, Jeffrey M

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Evaluation of pre-analytical factors affecting plasma DNA analysis von Markus, Havell, Contente-Cuomo, Tania, Farooq, Maria, Liang, Winnie S., Borad, Mitesh J., Sivakumar, Shivan, Gollins, Simon, Tran, Nhan L., Dhruv, Harshil D., Berens, Michael E., Bryce, Alan, Sekulic, Aleksandar, Ribas, Antoni, Trent, Jeffrey M., LoRusso, Patricia M., Murtaza, Muhammed

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Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type von Karnezis, Anthony N, Wang, Yemin, Ramos, Pilar, Hendricks, William PD, Oliva, Esther, D'Angelo, Emanuela, Prat, Jaime, Nucci, Marisa R, Nielsen, Torsten O, Chow, Christine, Leung, Samuel, Kommoss, Friedrich, Kommoss, Stefan, Silva, Annacarolina, Ronnett, Brigitte M, Rabban, Joseph T, Bowtell, David D, Weissman, Bernard E, Trent, Jeffrey M, Gilks, C Blake, Huntsman, David G

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Toward precision medicine in glioblastoma: the promise and the challenges von Prados, Michael D, Byron, Sara A, Tran, Nhan L, Phillips, Joanna J, Molinaro, Annette M, Ligon, Keith L, Wen, Patrick Y, Kuhn, John G, Mellinghoff, Ingo K, de Groot, John F, Colman, Howard, Cloughesy, Timothy F, Chang, Susan M, Ryken, Timothy C, Tembe, Waibhav D, Kiefer, Jeffrey A, Berens, Michael E, Craig, David W, Carpten, John D, Trent, Jeffrey M

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Identification of Recurrent Activating HER2 Mutations in Primary Canine Pulmonary Adenocarcinoma von Lorch, Gwendolen, Sivaprakasam, Karthigayini, Zismann, Victoria, Perdigones, Nieves, Contente-Cuomo, Tania, Nazareno, Alexandra, Facista, Salvatore, Wong, Shukmei, Drenner, Kevin, Liang, Winnie S, Amann, Joseph M, Sinicropi-Yao, Sara L, Koenig, Michael J, La Perle, Krista, Whitsett, Timothy G, Murtaza, Muhammed, Trent, Jeffrey M, Carbone, David P, Hendricks, William P D

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Improved methods for RNAseq-based alternative splicing analysis von Halperin, Rebecca F., Hegde, Apurva, Lang, Jessica D., Raupach, Elizabeth A., Legendre, Christophe, Liang, Winnie S., LoRusso, Patricia M., Sekulic, Aleksandar, Sosman, Jeffrey A., Trent, Jeffrey M., Rangasamy, Sampathkumar, Pirrotte, Patrick, Schork, Nicholas J.

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A BAP1 mutation in a Danish family predisposes to uveal melanoma and other cancers von Aoude, Lauren G, Wadt, Karin, Bojesen, Anders, Crüger, Dorthe, Borg, Ake, Trent, Jeffrey M, Brown, Kevin M, Gerdes, Anne-Marie, Jönsson, Göran, Hayward, Nicholas K

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Ponatinib Shows Potent Antitumor Activity in Small Cell Carcinoma of the Ovary Hypercalcemic Type (SCCOHT) through Multikinase Inhibition von Lang, Jessica D, Hendricks, William P D, Orlando, Krystal A, Yin, Hongwei, Kiefer, Jeffrey, Ramos, Pilar, Sharma, Ritin, Pirrotte, Patrick, Raupach, Elizabeth A, Sereduk, Chris, Tang, Nanyun, Liang, Winnie S, Washington, Megan, Facista, Salvatore J, Zismann, Victoria L, Cousins, Emily M, Major, Michael B, Wang, Yemin, Karnezis, Anthony N, Sekulic, Aleksandar, Hass, Ralf, Vanderhyden, Barbara C, Nair, Praveen, Weissman, Bernard E, Huntsman, David G, Trent, Jeffrey M

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Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib von Goodall, Megan L, Wang, Tong, Martin, Katie R, Kortus, Matthew G, Kauffman, Audra L, Trent, Jeffrey M, Gately, Stephen, MacKeigan, Jeffrey P

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A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters von Kang, Hyun-Jin, Cui, Yunxi, Yin, Holly, Scheid, Amy, Hendricks, William P. D, Schmidt, Jessica, Sekulic, Aleksandar, Kong, Deming, Trent, Jeffrey M, Gokhale, Vijay, Mao, Hanbin, Hurley, Laurence H

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Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer von Azorsa, David O, Gonzales, Irma M, Basu, Gargi D, Choudhary, Ashish, Arora, Shilpi, Bisanz, Kristen M, Kiefer, Jeffrey A, Henderson, Meredith C, Trent, Jeffrey M, Von Hoff, Daniel D, Mousses, Spyro

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Genome and transcriptome sequencing in prospective metastatic triple-negative breast cancer uncovers therapeutic vulnerabilities von Craig, David W, O'Shaughnessy, Joyce A, Kiefer, Jeffrey A, Aldrich, Jessica, Sinari, Shripad, Moses, Tracy M, Wong, Shukmei, Dinh, Jennifer, Christoforides, Alexis, Blum, Joanne L, Aitelli, Cristi L, Osborne, Cynthia R, Izatt, Tyler, Kurdoglu, Ahmet, Baker, Angela, Koeman, Julie, Barbacioru, Catalin, Sakarya, Onur, De La Vega, Francisco M, Siddiqui, Asim, Hoang, Linh, Billings, Paul R, Salhia, Bodour, Tolcher, Anthony W, Trent, Jeffrey M, Mousses, Spyro, Von Hoff, Daniel, Carpten, John D

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The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type von Wang, Yemin, Chen, Shary Yuting, Karnezis, Anthony N, Colborne, Shane, Santos, Nancy Dos, Lang, Jessica D, Hendricks, William PD, Orlando, Krystal A, Yap, Damian, Kommoss, Friedrich, Bally, Marcel B, Morin, Gregg B, Trent, Jeffrey M, Weissman, Bernard E, Huntsman, David G

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Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma von Weeraratna, Ashani T., Jiang, Yuan, Hostetter, Galen, Rosenblatt, Kevin, Duray, Paul, Bittner, Michael, Trent, Jeffrey M.

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Genome-wide association study for serum complement C3 and C4 levels in healthy Chinese subjects von Yang, Xiaobo, Sun, Jielin, Gao, Yong, Tan, Aihua, Zhang, Haiying, Hu, Yanling, Feng, Junjie, Qin, Xue, Tao, Sha, Chen, Zhuo, Kim, Seong-Tae, Peng, Tao, Liao, Ming, Lin, Xiaoling, Zhang, Zengfeng, Tang, Minzhong, Li, Li, Mo, Linjian, Liang, Zhengjia, Shi, Deyi, Huang, Zhang, Huang, Xianghua, Liu, Ming, Liu, Qian, Zhang, Shijun, Trent, Jeffrey M, Zheng, S Lilly, Xu, Jianfeng, Mo, Zengnan

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HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases von Kogler, Melanie, Tortola, Luigi, Negri, Gian Luca, Leopoldi, Alexandra, El-Naggar, Amal M., Mereiter, Stefan, Gomez-Diaz, Carlos, Nitsch, Roberto, Tortora, Davide, Kavirayani, Anoop M., Gapp, Bianca, Rao, Shuan, Uribesalgo, Iris, Hoffmann, David, Cikes, Domagoj, Novatchkova, Maria, Williams, David A., Trent, Jeffrey M., Ikeda, Fumiyo, Daugaard, Mads, Hagelkruys, Astrid, Sorensen, Poul H., Penninger, Josef M.

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