Transcriptional Subtypes Resolve Tumor Heterogeneity and Identify Vulnerabilities to MEK Inhibition in Lung Adenocarcinoma von Daemen, Anneleen, Cooper, Jonathan E., Myrta, Szymon, Wongchenko, Matthew J., Lin, Eva, Long, Jason E., Foreman, Oded, Modrusan, Zora, Tremayne, Jarrod R., de la Cruz, Cecile C., Merchant, Mark, Martin, Scott E., Yan, Yibing, Junttila, Melissa R.

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Interactions between MUC1 and p120 Catenin Regulate Dynamic Features of Cell Adhesion, Motility, and Metastasis von XIANG LIU, CHUNHUI YI, YUNFEI WEN, RADHAKRISHNAN, Prakash, TREMAYNE, Jarrod R, THONGTAN DAO, JOHNSON, Keith R, HOLLINGSWORTH, Michael A

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Cyclin-Dependent Kinase 5 Is Amplified and Overexpressed in Pancreatic Cancer and Activated by Mutant K-Ras von EGGERS, John P, GRANDGENETT, Paul M, OUELLETTE, Michel, HOLLINGSWORTH, Michael A, COLLISSON, Eric C, LEWALLEN, Michelle E, TREMAYNE, Jarrod, SINGH, Pankaj K, SWANSON, Benjamin J, ANDERSEN, Judy M, CAFFREY, Thomas C, HIGH, Robin R

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Abstract PO-101: Transcriptional heterogeneity in lung adenocarcinoma reveals distinct therapeutic vulnerabilities von Daemen, Anneleen, Cooper, Jonathan E., Myrta, Szymon, Wongchenko, Matthew J., Lin, Eva, Long, Jason E., Foreman, Oded, Modrusan, Zora, Tremayne, Jarrod, de la Cruz, Cecile C., Merchant, Mark, Martin, Scott E., Yan, Yibing, Junttila, Melissa R.

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P21-Activated Kinase 1 (PAK1) as a Therapeutic Target in BRAF Wild-Type Melanoma von ONG, Christy C, JUBB, Adrian M, HARRIS, Adrian L, FRIEDMAN, Lori S, BELVIN, Marcia, MIDDLETON, Mark R, BLACKWOOD, Elizabeth M, KOEPPEN, Hartmut, HOEFLICH, Klaus P, JAKUBIAK, Diana, WEI ZHOU, RUDOLPH, Joachim, HAVERTY, Peter M, KOWANETZ, Marcin, YIBING YAN, TREMAYNE, Jarrod, LISLE, Richard

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An Anti-B7-H4 Antibody–Drug Conjugate for the Treatment of Breast Cancer von Leong, Steven R, Liang, Wei-Ching, Wu, Yan, Crocker, Lisa, Cheng, Eric, Sampath, Deepak, Ohri, Rachana, Raab, Helga, Hass, Philip E, Pham, Thinh, Firestein, Ron, Li, Dongwei, Schutten, Melissa, Stagg, Nicola J, Ogasawara, Annie, Koppada, Neelima, Roth, Leslie, Williams, Simon P, Lee, Byoung-Chul, Chalouni, Cecile, Peng, Ivan, DeVoss, Jason, Tremayne, Jarrod, Polakis, Paul, Polson, Andrew G

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Cyclin Dependent Kinase 5 is amplified and over-expressed in pancreatic cancer and activated by mutant K-Ras von Eggers, John P., Grandgenett, Paul M., Collisson, Eric C., Lewallen, Michelle E., Tremayne, Jarrod, Singh, Pankaj K., Swanson, Benjamin J., Andersen, Judy M., Caffrey, Thomas C., High, Robin R., Ouellette, Michel, Hollingsworth, Michael A.

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