The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II von Lorenzen, Inken, Lokau, Juliane, Düsterhöft, Stefan, Trad, Ahmad, Garbers, Christoph, Scheller, Jürgen, Rose-John, Stefan, Grötzinger, Joachim

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Benefits and burden of the maternally-mediated immunological imprinting von Lemke, Hilmar, Tanasa, Radu Iulian, Trad, Ahmad, Lange, Hans

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Toll-like receptors on the fork roads between innate and adaptive immunity von Abdelsadik, Ahmed, Trad, Ahmad

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A Disintegrin and Metalloprotease (ADAM) 10 and ADAM17 Are Major Sheddases of T Cell Immunoglobulin and Mucin Domain 3 (Tim-3) von Möller-Hackbarth, Katja, Dewitz, Christin, Schweigert, Olga, Trad, Ahmad, Garbers, Christoph, Rose-John, Stefan, Scheller, Jürgen

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Multimerisation of A disintegrin and metalloprotease protein-17 (ADAM17) is mediated by its EGF-like domain von Lorenzen, Inken, Trad, Ahmad, Grötzinger, Joachim

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Soluble T cell immunoglobulin and mucin domain (TIM)-1 and -4 generated by A Disintegrin And Metalloprotease (ADAM)-10 and -17 bind to phosphatidylserine von Schweigert, Olga, Dewitz, Christin, Möller-Hackbarth, Katja, Trad, Ahmad, Garbers, Christoph, Rose-John, Stefan, Scheller, Jürgen

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Alternative Intronic Polyadenylation Generates the Interleukin-6 Trans-signaling Inhibitor sgp130-E10 von Sommer, Jan, Garbers, Christoph, Wolf, Janina, Trad, Ahmad, Moll, Jens M., Sack, Markus, Fischer, Rainer, Grötzinger, Joachim, Waetzig, Georg H., Floss, Doreen M., Scheller, Jürgen

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The proteases HtrA2/Omi and UCH-L1 regulate TNF-induced necroptosis von Sosna, Justyna, Voigt, Susann, Mathieu, Sabine, Kabelitz, Dieter, Trad, Ahmad, Janssen, Ottmar, Meyer-Schwesinger, Catherine, Schütze, Stefan, Adam, Dieter

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Abstract 1811: AFVT-2101: A FRα × CD16A bispecific innate cell engager for the treatment of solid tumors von Rigamonti, Nicolo', Schmollinger, Jan, Sandy, Peter, Tomaszowski, Michael, Caslavsky, Josef, Trad, Ahmad, O’Shannessy, Daniel, Siegler, Jana, Gaukel, Eric J., Penston, Daniela, Reusch, Uwe, Johnson, Zoë

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CD30 on extracellular vesicles from malignant Hodgkin cells supports damaging of CD30 ligand-expressing bystander cells with Brentuximab-Vedotin, in vitro von Hansen, Hinrich P, Trad, Ahmad, Dams, Maria, Zigrino, Paola, Moss, Marcia, Tator, Maximilian, Schön, Gisela, Grenzi, Patricia C, Bachurski, Daniel, Aquino, Bruno, Dürkop, Horst, Reiners, Katrin S, von Bergwelt-Baildon, Michael, Hallek, Michael, Grötzinger, Joachim, Engert, Andreas, Paes Leme, Adriana F, Pogge von Strandmann, Elke

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A novel bispecific single-chain antibody for ADAM17 and CD3 induces T-cell-mediated lysis of prostate cancer cells von Yamamoto, Kosuke, Trad, Ahmad, Baumgart, Anja, Hüske, Linda, Lorenzen, Inken, Chalaris, Athena, Grötzinger, Joachim, Dechow, Tobias, Scheller, Jürgen, Rose-John, Stefan

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The disintegrin domain of ADAM17 antagonises fibroblast-carcinoma cell interactions von TRAD, AHMAD, RIESE, MICHEL, SHOMALI, MOHAMMAD, HEDEMAN, NINA, EFFENBERGER, TIMO, GRÖTZINGER, JOACHIM, LORENZEN, INKEN

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Development of sandwich ELISA for detection and quantification of human and murine a disintegrin and metalloproteinase17 von Trad, Ahmad, Hedemann, Nina, Shomali, Mohammad, Pawlak, Verena, Grötzinger, Joachim, Lorenzen, Inken

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1212 AFVT-2101, an innate immune-cell engager that selectively targets FOLR1 expressing tumor cells to safely harness potent anti-cancer responses von Trad, Ahmad, Tomaszowski, Michael, Caslavsky, Josef, Freitag, Robert, Haan, Keith, Rohrwild, Markus, Daniel O’Shannessy, Siegler, Jana, Penugonda, Sudhir, Sandy, Peter, Gaukel, Eric, Penston, Daniela, Johnson, Zoë

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Upd3 – An ancestor of the four-helix bundle cytokines von Oldefest, Mirja, Nowinski, Jana, Hung, Chien-Wen, Neelsen, Denis, Trad, Ahmad, Tholey, Andreas, Grötzinger, Joachim, Lorenzen, Inken

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Clinicopathologic characteristics and patient outcomes of malignant phyllodes tumors: A multi-institution experience von Al-Awadhi, Aydah, Hussein, Mawada, Al Qawasmeh, Khaled H, Trad, Diaeddine Ahmad, Ansari, Jawaher, Anwar, Emad, Bennini, Nouri, Azribi, Fathi

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Molecular basis of antibody binding to mucin glycopeptides in lung cancer von QU, JIN, YU, HONGTAO, LI, FENGE, ZHANG, CHUNLEI, TRAD, AHMAD, BROOKS, CORY, ZHANG, BIN, GONG, TING, GUO, ZHI, LI, YUNSEN, RAGUPATHI, GOVIND, LOU, YANYAN, HWU, PATRICK, HUANG, WEI, ZHOU, DAPENG

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Repertoire restriction of immunoglobulin DH gene segments impairs T cell regulation of a thymus-dependent immune response (62.7) von Lemke, Hilmar, Trad, Ahmad, Tanasa, Radu, Zemlin, Michael, Schroeder, Harry

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ADAM17-overexpressing breast cancer cells selectively targeted by antibody–toxin conjugates von Trad, Ahmad, Hansen, Hinrich P., Shomali, Mohammad, Peipp, Matthias, Klausz, Katja, Hedemann, Nina, Yamamoto, Kosuke, Mauermann, André, Desel, Christine, Lorenzen, Inken, Lemke, Hilmar, Rose-John, Stefan, Grötzinger, Joachim

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Immunoglobulin class switching appears to be regulated by B‐cell antigen receptor‐specific T‐cell action von Lange, Hans, Hecht, Oliver, Zemlin, Michael, Trad, Ahmad, Tanasa, Radu I., Schroeder, Harry W., Lemke, Hilmar

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