Clinical-genomic determinants of immune checkpoint blockade response in head and neck squamous cell carcinoma von Valero, Cristina, Golkaram, Mahdi, Vos, Joris L, Xu, Bin, Fitzgerald, Conall, Lee, Mark, Kaplan, Shannon, Han, Catherine Y, Pei, Xin, Sarkar, Reith, Boe, Lillian A, Pandey, Abhinav, Koh, Elizabeth S, Zuur, Charlotte L, Solit, David B, Pawlowski, Traci, Liu, Li, Ho, Alan L, Chowell, Diego, Riaz, Nadeem, Chan, Timothy A, Morris, Luc Gt

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Identification of genetic variants using bar-coded multiplexed sequencing von Craig, David W, Pearson, John V, Szelinger, Szabolcs, Sekar, Aswin, Redman, Margot, Corneveaux, Jason J, Pawlowski, Traci L, Laub, Trisha, Nunn, Gary, Stephan, Dietrich A, Homer, Nils, Huentelman, Matthew J

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Identification of biomarkers predictive of metastasis development in early-stage colorectal cancer using network-based regularization von Peixoto, Carolina, Lopes, Marta B, Martins, Marta, Casimiro, Sandra, Sobral, Daniel, Grosso, Ana Rita, Abreu, Catarina, Macedo, Daniela, Costa, Ana Lúcia, Pais, Helena, Alvim, Cecília, Mansinho, André, Filipe, Pedro, Costa, Pedro Marques da, Fernandes, Afonso, Borralho, Paula, Ferreira, Cristina, Malaquias, João, Quintela, António, Kaplan, Shannon, Golkaram, Mahdi, Salmans, Michael, Khan, Nafeesa, Vijayaraghavan, Raakhee, Zhang, Shile, Pawlowski, Traci, Godsey, Jim, So, Alex, Liu, Li, Costa, Luís, Vinga, Susana

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Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder von Napolioni, Valerio, Ober-Reynolds, Benjamin, Szelinger, Szabolcs, Corneveaux, Jason J, Pawlowski, Traci, Ober-Reynolds, Sharman, Kirwan, Janet, Persico, Antonio M, Melmed, Raun D, Craig, David W, Smith, Christopher J, Huentelman, Matthew J

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Hippocampal gene expression changes during age-related cognitive decline von Pawlowski, Traci L, Bellush, Linda L, Wright, Amy W, Walker, Jon P, Colvin, Robert A, Huentelman, Matthew J

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Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy von Krishna, Chirag, DiNatale, Renzo G., Kuo, Fengshen, Srivastava, Raghvendra M., Vuong, Lynda, Chowell, Diego, Gupta, Sounak, Vanderbilt, Chad, Purohit, Tanaya A., Liu, Ming, Kansler, Emily, Nixon, Briana G., Chen, Ying-Bei, Makarov, Vladimir, Blum, Kyle A., Attalla, Kyrollis, Weng, Stanley, Salmans, Michael L., Golkaram, Mahdi, Liu, Li, Zhang, Shile, Vijayaraghavan, Raakhee, Pawlowski, Traci, Reuter, Victor, Carlo, Maria I., Voss, Martin H., Coleman, Jonathan, Russo, Paul, Motzer, Robert J., Li, Ming O., Leslie, Christina S., Chan, Timothy A., Hakimi, A. Ari

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AT2 Receptor-Interacting Proteins ATIPs in the Brain von Rodrigues-Ferreira, Sylvie, le Rouzic, Erwann, Pawlowski, Traci, Srivastava, Anand, Margottin-Goguet, Florence, Nahmias, Clara

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Candidate Agtr2 influenced genes and pathways identified by expression profiling in the developing brain of Agtr2(-/y) mice von Pawlowski, Traci L, Heringer-Walther, Silvia, Cheng, Chun-Huai, Archie, John G, Chen, Chin-Fu, Walther, Thomas, Srivastava, Anand K

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Abstract 175: Illumina RNA-sequencing for biomarker analysis from FFPE and fresh frozen tumor specimens von Salmans, Michael, Golkaram, Mahdi, Yao, Joyee, Zhang, Shile, Liu, Li, Pawlowski, Traci

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Candidate Agtr2 influenced genes and pathways identified by expression profiling in the developing brain of Agtr2 −/y mice von Pawlowski, Traci L., Heringer-Walther, Silvia, Cheng, Chun-Huai, Archie, John G., Chen, Chin-Fu, Walther, Thomas, Srivastava, Anand K.

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Abstract 1346: Panel-based tumor mutational burden (TMB) analysis of matched tumor and plasma specimens using Illumina’s TruSight Oncology 500 next-generation sequencing assay von Hastings, Stephanie B., Hariani, Gunjan, Weigman, Victor J., Jiang, Tingting, Zhao, Chen, Raja, Rajiv, Pawlowski, Traci, Brohawn, Philip, Hurban, Patrick

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Abstract 1993: A comprehensive benchmarking of paired whole exome and transcriptome biomarker analysis of response to cancer immunotherapy von Golkaram, Mahdi, Salmans, Michael, Vijayaraghavan, Raakhee, Kaplan, Shannon, Haigis, Robert, Yao, Joyee, Kruglyak, Kristina, Liu, Li, Pawlowski, Traci, Bilke, Sven, Zhang, Shile

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Molecular profiling of ctDNA from NCI-MATCH patients enrolled for treatment with mTOR1/2 inhibitor sapanisertib (arm M) and the Hedgehog pathway inhibitor vismodegib (arm T) von LoCoco, Jennifer S., Das, Biswajit, Rahmanian, Sorena, Chang, Ting-Chia, Silhavy, Jennifer, Chen, Li, Harrington, Robin, Peach, Amanda, Fu, Yao, McShane, Lisa, Li, Jessica, Chen, Alice P., Takebe, Naoko, Harris, Lyndsay, Patton, David R., Pawlowski, Traci L., Febbo, Phillip G., Doroshow, James H., Williams, P. Mickey, Karlovich, Chris Alan

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Blood-based assessment of patients with mismatch repair-deficient tumors enrolled in NCI-MATCH Arm Z1D (nivolumab) von Karlovich, Chris Alan, Silhavy, Jennifer, LoCoco, Jennifer S., Das, Biswajit, Rahmanian, Sorena, Chang, Ting-Chia, Peach, Amanda, Harrington, Robin, Chen, Li, Harris, Lyndsay, Fu, Yao, Patton, David R., Li, Jessica, Chen, Alice P., Takebe, Naoko, Pawlowski, Traci L., McShane, Lisa, Febbo, Phillip G., Doroshow, James H., Williams, P. Mickey

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Blood-based detection of actionable alterations from NCI-MATCH patients with no tissue results von Harrington, Robin, Peach, Amanda, Howell, D'Andra, Das, Biswajit, Pauly, Rini, Chang, Ting-Chia, LoCoco, Jennifer S., Chen, Li, Jiwani, Shahanawaz, Lee, Jennifer, McShane, Lisa, Chen, Alice P., Febbo, Phillip G., Pawlowski, Traci L., Takebe, Naoko, Tricoli, James V., Doroshow, James H., Williams, Paul M., Karlovich, Chris Alan

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Abstract 435: Accurate measurement of tumor mutation burden through tumor-only sequencing using a 500-gene panel von So, Alex Steven, Kaplan, Shannon, Zhao, Chen, Zhang, Shile, Liu, Li, Le, Phillip, Vijayaraghavan, Raakhee, Jiang, Tingting, Bilke, Sven, Pawlowski, Traci, Gutekunst, Karen

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Spatiotemporal evolution of the clear cell renal cell carcinoma microenvironment links intra-tumoral heterogeneity to immune escape von Golkaram, Mahdi, Kuo, Fengshen, Gupta, Sounak, Carlo, Maria I, Salmans, Michael L, Vijayaraghavan, Raakhee, Tang, Cerise, Makarov, Vlad, Rappold, Phillip, Blum, Kyle A, Zhao, Chen, Mehio, Rami, Zhang, Shile, Godsey, Jim, Pawlowski, Traci, DiNatale, Renzo G, Morris, Luc G T, Durack, Jeremy, Russo, Paul, Kotecha, Ritesh R, Coleman, Jonathan, Chen, Ying-Bei, Reuter, Victor E, Motzer, Robert J, Voss, Martin H, Liu, Li, Reznik, Ed, Chan, Timothy A, Hakimi, A Ari

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Identification of a Common Variant Affecting Human Episodic Memory Performance Using a Pooled Genome-Wide Association Approach: A Case Study of Disease Gene Identification von Pawlowski, Traci L., Huentelman, Matthew J.

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Genetic and microenvironmental intra-tumor heterogeneity impacts colorectal cancer evolution and metastatic development von Sobral, Daniel, Martins, Marta, Kaplan, Shannon, Golkaram, Mahdi, Salmans, Michael, Khan, Nafeesa, Vijayaraghavan, Raakhee, Cara de Anjo Casimiro, Sandra Cristina, Fernandes, Afonso, Borralho Nunes, Paula, Ferreira, Cristina, Pinto, Rui, Marques, Catarina, Costa, Ana Lúcia, Zhang, Shile, Pawlowski, Traci, Godsey, Jim, Mansinho, André, Macedo, Daniela, Lobo-Martins, Soraia, Filipe, Pedro, Esteves, Rui, Coutinho, Joao Manuel Rodrigues, Costa, Paulo Matos, Ramires, Afonso, Aldeia, Fernando, Quintela, António, So, Alex, Liu, Li, Grosso, Ana Rita, Costa, Luis

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Abstract 4954: Comparison of miR expression patterns in plasma, serum, and cell line cMV von Pawlowski, Traci L., Yeatts, Kimberly, Millis, Meredith, Radebach, Katrina, Kojima, Yuka, Zhong, Jason, Stark, Adam, Kuslich, Christine

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