Therapy of experimental NASH and fibrosis with galectin inhibitors von Traber, Peter G, Zomer, Eliezer

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Regression of fibrosis and reversal of cirrhosis in rats by galectin inhibitors in thioacetamide-induced liver disease von Traber, Peter G, Chou, Hsin, Zomer, Eliezer, Hong, Feng, Klyosov, Anatole, Fiel, Maria-Isabel, Friedman, Scott L

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Utility and variability of three non-invasive liver fibrosis imaging modalities to evaluate efficacy of GR-MD-02 in subjects with NASH and bridging fibrosis during a phase-2 random... von Harrison, Stephen A, Dennis, Andrea, Fiore, Martine M, Kelly, Matt D, Kelly, Catherine J, Paredes, Angelo H, Whitehead, Jennifer M, Neubauer, Stefan, Traber, Peter G, Banerjee, Rajarshi

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Galectin-3 inhibition with belapectin combined with anti-OX40 therapy reprograms the tumor microenvironment to favor anti-tumor immunity von Sturgill, Elizabeth R., Rolig, Annah S., Linch, Stefanie N., Mick, Courtney, Kasiewicz, Melissa J., Sun, Zhaoyu, Traber, Peter G., Shlevin, Harold, Redmond, William L.

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Binding of polysaccharides to human galectin-3 at a noncanonical site in its carbohydrate recognition domain von Miller, Michelle C, Ippel, Hans, Suylen, Dennis, Klyosov, Anatole A, Traber, Peter G, Hackeng, Tilman, Mayo, Kevin H

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Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor von Curti, Brendan D, Koguchi, Yoshinobu, Leidner, Rom S, Rolig, Annah S, Sturgill, Elizabeth R, Sun, Zhaoyu, Wu, Yaping, Rajamanickam, Venkatesh, Bernard, Brady, Hilgart-Martiszus, Ian, Fountain, Christopher B, Morris, George, Iwamoto, Noriko, Shimada, Takashi, Chang, ShuChing, Traber, Peter G, Zomer, Eliezer, Horton, J Rex, Shlevin, Harold, Redmond, William L

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Phase 2 Dose-Finding Study in Patients with Gout Using SEL-212, a Novel PEGylated Uricase (SEL-037) Combined with Tolerogenic Nanoparticles (SEL-110) von Kivitz, Alan, DeHaan, Wesley, Azeem, Rehan, Park, Justin, Rhodes, Sheri, Inshaw, Jamie, Leung, Sheldon S., Nicolaou, Savvas, Johnston, Lloyd, Kishimoto, Takashi K., Traber, Peter G., Sands, Earl, Choi, Hyon

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Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal Hypertension von Chalasani, Naga, Abdelmalek, Manal F., Garcia-Tsao, Guadalupe, Vuppalanchi, Raj, Alkhouri, Naim, Rinella, Mary, Noureddin, Mazen, Pyko, Maxmillan, Shiffman, Mitchell, Sanyal, Arun, Allgood, Adam, Shlevin, Harold, Horton, Rex, Zomer, Eliezer, Irish, William, Goodman, Zachary, Harrison, Stephen A., Traber, Peter G., Abdelmalek, Manal, Balart, Luis, Borg, Brian, Chalasani, Naga, Charlton, Michael, Conjeevaram, Hari, Fuchs, Michael, Ghalib, Reem, Gholam, Pierre, Halegoua-De Marzio, Dina, Harrison, Stephen, Jue, Christopher, Kemmer, Nyingi, Kowdley, Kris, Lai, Michelle, Lawitz, Eric, Loomba, Rohit, Noureddin, Mazen, Paredes, Angelo, Rinella, Mary, Rockey, Don, Rodriguez, Miguel, Rubin, Raymond, Ryan, Michael, Sanyal, Arun, Scanga, Andrew, Sepe, Thomas, Shiffman, Mitchell, Tetri, Brent, Thuluvath, Paul, Torres, Dawn, Vierling, John, Wattacheril, Julia, Weiland, Amanda, Zogg, Donald

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The COMPARE head-to-head, randomized controlled trial of SEL-212 (pegadricase plus rapamycin-containing nanoparticle, ImmTOR™) versus pegloticase for refractory gout von Baraf, Herbert S B, Khanna, Puja P, Kivitz, Alan J, Strand, Vibeke, Choi, Hyon K, Terkeltaub, Robert, Dalbeth, Nicola, DeHaan, Wesley, Azeem, Rehan, Traber, Peter G, Keenan, Robert T

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Rapamycin nanoparticles increase the therapeutic window of engineered interleukin-2 and drive expansion of antigen-specific regulatory T cells for protection against autoimmune dis... von Kishimoto, Takashi Kei, Fournier, Max, Michaud, Alicia, Rizzo, Gina, Roy, Christopher, Capela, Teresa, Nukolova, Natasha, Li, Ning, Doyle, Liam, Fu, Fen-ni, VanDyke, Derek, Traber, Peter G., Spangler, Jamie B., Leung, Sheldon S., Ilyinskii, Petr O.

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Cdx1 and Cdx2 expression during intestinal development von Silberg, Debra G., Swain, Gary P., Suh, Eun Ran, Traber, Peter G.

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Phosphorylation of the serine 60 residue within the Cdx2 activation domain mediates Its transactivation capacity von Rings, Edmond H.H.M., Boudreau, François, Taylor, Jennifer K., Mofett, Jennifer, Ran Suh, Eun, Traber, Peter G.

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DNA Methylation Down-regulates CDX1 Gene Expression in Colorectal Cancer Cell Lines von Suh, Eun Ran, Ha, Chong S., Rankin, Erinn B., Toyota, Minoru, Traber, Peter G.

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An intestine-specific homeobox gene regulates proliferation and differentiation von Suh, Eunran, Traber, Peter G.

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Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developm... von Boudreau, François, Rings, Edmond H H M, van Wering, Herbert M, Kim, Richard K, Swain, Gary P, Krasinski, Stephen D, Moffett, Jennifer, Grand, Richard J, Suh, Eun Ran, Traber, Peter G

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A Novel Colonic Repressor Element Regulates Intestinal Gene Expression by Interacting with Cux/CDP von Boudreau, François, Rings, Edmond H H M, Swain, Gary P, Sinclair, Angus M, Suh, Eun Ran, Silberg, Debra G, Scheuermann, Richard H, Traber, Peter G

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Sa1686 Galectin-3 (Gal-3) Expression in Relation to Fibrosis in Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) von Goodman, Zachary D, Mulder, Christopher, Bolduc, Caroline A, Raines, Matthew F, Cebe, Katherine M, Alaparthi, Lakshmi, Monge, Fanny, Traber, Peter G, Harrison, Stephen A

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P084 Gout symptom improvements and patient outcomes with SEL-212 in gout refractory to conventional therapy: DISSOLVE I & II phase 3, double-blind, placebo-controlled clinical tria... von Baraf, Herbert S B, Khanna, Puja, Patel, Anand, Sobierska, Joanna, Christie, Jacquie, DeHaan, Wesley, Azeem, Rehan, Traber, Peter G, Kivitz, Alan

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Surviving Hurricane Katrina: reconstructing the educational enterprise of Tulane University School of Medicine von Krane, N Kevin, Kahn, Marc J, Markert, Ronald J, Whelton, Paul K, Traber, Peter G, Taylor, Ian L

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The Caudal-related Homeodomain Protein Cdx1 Inhibits Proliferation of Intestinal Epithelial Cells by Down-regulation of D-type Cyclins von Lynch, John, Suh, Eun-Ran, Silberg, Debra G., Rulyak, Steven, Blanchard, Nadine, Traber, Peter G.

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