Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes von Lewis, Myles J., Barnes, Michael R., Blighe, Kevin, Goldmann, Katriona, Rana, Sharmila, Hackney, Jason A., Ramamoorthi, Nandhini, John, Christopher R., Watson, David S., Kummerfeld, Sarah K., Hands, Rebecca, Riahi, Sudeh, Rocher-Ros, Vidalba, Rivellese, Felice, Humby, Frances, Kelly, Stephen, Bombardieri, Michele, Ng, Nora, DiCicco, Maria, van der Heijde, Désirée, Landewé, Robert, van der Helm-van Mil, Annette, Cauli, Alberto, McInnes, Iain B., Buckley, Christopher D., Choy, Ernest, Taylor, Peter C., Townsend, Michael J., Pitzalis, Costantino

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B-cell targeted therapies in human autoimmune diseases: an updated perspective von Townsend, Michael J, Monroe, John G, Chan, Andrew C

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Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration von Orozco, Luz D., Chen, Hsu-Hsin, Cox, Christian, Katschke, Kenneth J., Arceo, Rommel, Espiritu, Carmina, Caplazi, Patrick, Nghiem, Sarajane Saturnio, Chen, Ying-Jiun, Modrusan, Zora, Dressen, Amy, Goldstein, Leonard D., Clarke, Christine, Bhangale, Tushar, Yaspan, Brian, Jeanne, Marion, Townsend, Michael J., van Lookeren Campagne, Menno, Hackney, Jason A.

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Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in systemic lupus erythematosus von Tokuyama, Maria, Gunn, Bronwyn M, Venkataraman, Arvind, Kong, Yong, Kang, Insoo, Rakib, Tasfia, Townsend, Michael J, Costenbader, Karen H, Alter, Galit, Iwasaki, Akiko

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Molecular and cellular heterogeneity in the Rheumatoid Arthritis synovium: Clinical correlates of synovitis von Townsend, Michael J., Ph.D

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NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus von Brightbill, Hans D., Suto, Eric, Blaquiere, Nicole, Ramamoorthi, Nandhini, Sujatha-Bhaskar, Swathi, Gogol, Emily B., Castanedo, Georgette M., Jackson, Benjamin T., Kwon, Youngsu C., Haller, Susan, Lesch, Justin, Bents, Karin, Everett, Christine, Kohli, Pawan Bir, Linge, Sandra, Christian, Laura, Barrett, Kathy, Jaochico, Allan, Berezhkovskiy, Leonid M., Fan, Peter W., Modrusan, Zora, Veliz, Kelli, Townsend, Michael J., DeVoss, Jason, Johnson, Adam R., Godemann, Robert, Lee, Wyne P., Austin, Cary D., McKenzie, Brent S., Hackney, Jason A., Crawford, James J., Staben, Steven T., Alaoui Ismaili, Moulay H., Wu, Lawren C., Ghilardi, Nico

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transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes von Jenner, Richard G, Townsend, Michael J, Jackson, Ian, Sun, Kaiming, Bouwman, Russell D, Young, Richard A, Glimcher, Laurie H, Lord, Graham M

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Ability of Interleukin‐33– and Immune Complex–Triggered Activation of Human Mast Cells to Down‐Regulate Monocyte‐Mediated Immune Responses von Rivellese, Felice, Suurmond, Jolien, Habets, Kim, Dorjée, Annemarie L., Ramamoorthi, Nandhini, Townsend, Michael J., de Paulis, Amato, Marone, Gianni, Huizinga, Tom W. J., Pitzalis, Costantino, Toes, René E. M.

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Modular Analysis of Peripheral Blood Gene Expression in Rheumatoid Arthritis Captures Reproducible Gene Expression Changes in Tumor Necrosis Factor Responders von Oswald, Michaela, Curran, Mark E., Lamberth, Sarah L., Townsend, Robert M., Hamilton, Jennifer D., Chernoff, David N., Carulli, John, Townsend, Michael J., Weinblatt, Michael E., Kern, Marlena, Pond, Cassandra M., Lee, Annette, Gregersen, Peter K.

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Promising bone-related therapeutic targets for rheumatoid arthritis von Choi, Yongwon, Arron, Joseph R, Townsend, Michael J

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Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration von Orozco, Luz D., Chen, Hsu-Hsin, Cox, Christian, Katschke, Kenneth J., Rommel Arceo, Espiritu, Carmina, Caplazi, Patrick, Nghiem, Sarajane Saturnio, Chen, Ying-Jiun, Modrusan, Zora, Dressen, Amy, Goldstein, Leonard D., Clarke, Christine, Bhangale, Tushar, Yaspan, Brian, Jeanne, Marion, Townsend, Michael J., van Lookeren Campagne, Menno, Hackney, Jason A.

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The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation von Senger, Kate, Pham, Victoria C, Varfolomeev, Eugene, Hackney, Jason A, Corzo, Cesar A, Collier, Jenna, Lau, Vivian W C, Huang, Zhiyu, Hamidzhadeh, Kajal, Caplazi, Patrick, Peng, Ivan, Setiadi, A Francesca, Francis, Ross, Paler-Martinez, Andres, Kwon, Youngsu C, Ramirez-Carrozzi, Vladimir, Sun, Yonglian, Grigg, Patricia W, Roose-Girma, Merone, Jeet, Surinder, Barck, Kai H, Pham, Anna, Ota, Naruhisa, Ha, Connie, Stinson, Jeremy, Guillory, Joseph, Tam, Lucinda, Modrusan, Zora, Emson, Claire, McKenzie, Brent S, Townsend, Michael J, Carano, Richard A D, Warming, Søren, Vucic, Domagoj, DeVoss, Jason, Lee, Wyne P, Lill, Jennie R, Zarrin, Ali A

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Efficacy and safety of pateclizumab (anti-lymphotoxin-α) compared to adalimumab in rheumatoid arthritis: a head-to-head phase 2 randomized controlled study (The ALTARA Study) von Kennedy, William P, Simon, J Abraham, Offutt, Carolyn, Horn, Priscilla, Herman, Ann, Townsend, Michael J, Tang, Meina T, Grogan, Jane L, Hsieh, Frank, Davis, John C

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A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-α) in patients with systemic lupus erythematosus (ROSE) von Kalunian, Kenneth C, Merrill, Joan T, Maciuca, Romeo, McBride, Jacqueline M, Townsend, Michael J, Wei, Xiaohui, Davis, John C, Kennedy, William P

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Characterization of IL-17AA and IL-17FF in rheumatoid arthritis and multiple sclerosis von Schofield, Cheryl, Fischer, Saloumeh K, Townsend, Michael J, Mosesova, Sofia, Peng, Kun, Setiadi, Alvernia Francesca, Song, An, Baruch, Amos

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IL-4 Induces Characteristic Th2 Responses Even in the Combined Absence of IL-5, IL-9, and IL-13 von Fallon, Padraic G., Jolin, Helen E., Smith, Philippa, Emson, Claire L., Townsend, Michael J., Fallon, Rosie, Smith, Philip, McKenzie, Andrew N.J.

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Levels of CXCL13 and sICAM-1 correlate with disease activity score in patients with rheumatoid arthritis treated with tocilizumab von Tuckwell, Katie, Gabay, Cem, Sornasse, Thierry, Laubender, Ruediger Paul, Wang, Jianmei, Townsend, Michael J

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Efficacy, Safety, and Pharmacodynamic Effects of the Bruton’s Tyrosine Kinase Inhibitor Fenebrutinib (GDC‐0853) in Systemic Lupus Erythematosus: Results of a Phase II, Randomized,... von Isenberg, David, Furie, Richard, Jones, Nicholas S., Guibord, Pascal, Galanter, Joshua, Lee, Chin, McGregor, Anna, Toth, Balazs, Rae, Julie, Hwang, Olivia, Desai, Rupal, Lokku, Armend, Ramamoorthi, Nandhini, Hackney, Jason A., Miranda, Pedro, Souza, Viviane A., Jaller‐Raad, Juan J., Maura Fernandes, Anna, Garcia Salinas, Rodrigo, Chinn, Leslie W., Townsend, Michael J., Morimoto, Alyssa M., Tuckwell, Katie

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SIGN-R1 contributes to protection against lethal pneumococcal infection in mice von Lanoue, Astrid, Clatworthy, Menna R, Smith, Philippa, Green, Sheila, Townsend, Michael J, Jolin, Helen E, Smith, Kenneth G C, Fallon, Padraic G, McKenzie, Andrew N J

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Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics von Dennis, Jr, Glynn, Holweg, Cécile T J, Kummerfeld, Sarah K, Choy, David F, Setiadi, A Francesca, Hackney, Jason A, Haverty, Peter M, Gilbert, Houston, Lin, Wei Yu, Diehl, Lauri, Fischer, S, Song, An, Musselman, David, Klearman, Micki, Gabay, Cem, Kavanaugh, Arthur, Endres, Judith, Fox, David A, Martin, Flavius, Townsend, Michael J

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