Targeted Metabolomics of Tissue and Plasma Identifies Biomarkers in Mice with NOTCH1-Dependent T-Cell Acute Lymphoblastic Leukemia von Tosello, Valeria, Di Martino, Ludovica, Piovan, Erich

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Insights on Metabolic Reprogramming and Its Therapeutic Potential in Acute Leukemia von Di Martino, Ludovica, Tosello, Valeria, Peroni, Edoardo, Piovan, Erich

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Crosstalk between Hedgehog pathway and the glucocorticoid receptor pathway as a basis for combination therapy in T-cell acute lymphoblastic leukemia von Bongiovanni, Deborah, Tosello, Valeria, Saccomani, Valentina, Dalla Santa, Silvia, Amadori, Alberto, Zanovello, Paola, Piovan, Erich

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Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL von Tzoneva, Gannie, Perez-Garcia, Arianne, Carpenter, Zachary, Khiabanian, Hossein, Tosello, Valeria, Allegretta, Maddalena, Paietta, Elisabeth, Racevskis, Janis, Rowe, Jacob M, Tallman, Martin S, Paganin, Maddalena, Basso, Giuseppe, Hof, Jana, Kirschner-Schwabe, Renate, Palomero, Teresa, Rabadan, Raul, Ferrando, Adolfo

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Direct Reversal of Glucocorticoid Resistance by AKT Inhibition in Acute Lymphoblastic Leukemia von Piovan, Erich, Yu, Jiyang, Tosello, Valeria, Herranz, Daniel, Ambesi-Impiombato, Alberto, Da Silva, Ana Carolina, Sanchez-Martin, Marta, Perez-Garcia, Arianne, Rigo, Isaura, Castillo, Mireia, Indraccolo, Stefano, Cross, Justin R., de Stanchina, Elisa, Paietta, Elisabeth, Racevskis, Janis, Rowe, Jacob M., Tallman, Martin S., Basso, Giuseppe, Meijerink, Jules P., Cordon-Cardo, Carlos, Califano, Andrea, Ferrando, Adolfo A.

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BCAT1 is a NOTCH1 target and sustains the oncogenic function of NOTCH1 von Tosello, Valeria, Di Martino, Ludovica, Papathanassiu, Adonia E, Santa, Silvia Dalla, Pizzi, Marco, Mussolin, Lara, Liu, Jingjing, Van Vlierberghe, Pieter, Piovan, Erich

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Binary classification of copy number alteration profiles in liquid biopsy with potential clinical impact in advanced NSCLC von Tosello, Valeria, Grassi, Angela, Rose, Dominic, Bao, Loc Carlo, Zulato, Elisabetta, Dalle Fratte, Chiara, Polano, Maurizio, Del Bianco, Paola, Pasello, Giulia, Guarneri, Valentina, Indraccolo, Stefano, Bonanno, Laura

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DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia von Rampal, Raajit, Alkalin, Altuna, Madzo, Jozef, Vasanthakumar, Aparna, Pronier, Elodie, Patel, Jay, Li, Yushan, Ahn, Jihae, Abdel-Wahab, Omar, Shih, Alan, Lu, Chao, Ward, Patrick S, Tsai, Jennifer J, Hricik, Todd, Tosello, Valeria, Tallman, Jacob E, Zhao, Xinyang, Daniels, Danette, Dai, Qing, Ciminio, Luisa, Aifantis, Iannis, He, Chuan, Fuks, Francois, Tallman, Martin S, Ferrando, Adolfo, Nimer, Stephen, Paietta, Elisabeth, Thompson, Craig B, Licht, Jonathan D, Mason, Christopher E, Godley, Lucy A, Melnick, Ari, Figueroa, Maria E, Levine, Ross L

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Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination von Tosello, Valeria, Bongiovanni, Deborah, Liu, Jingjing, Pan, Qingfei, Yan, Koon-kiu, Saccomani, Valentina, Van Trimpont, Maaike, Pizzi, Marco, Mazzoni, Martina, Dei Tos, Angelo Paolo, Amadori, Alberto, Zanovello, Paola, Van Vlierberghe, Pieter, Yu, Jiyang, Piovan, Erich

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Chemotactic Cues for NOTCH1-Dependent Leukemia von Piovan, Erich, Tosello, Valeria, Amadori, Alberto, Zanovello, Paola

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Responsiveness to Hedgehog Pathway Inhibitors in T-Cell Acute Lymphoblastic Leukemia Cells Is Highly Dependent on 5 ' AMP-Activated Kinase Inactivation von Tosello, Valeria, Bongiovanni, Deborah, Di Martino, Ludovica, Franchin, Cinzia, Zanovello, Paola, Arrigoni, Giorgio, Piovan, Erich

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WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia von Bordin, Fulvio, Piovan, Erich, Masiero, Elena, Ambesi-Impiombato, Alberto, Minuzzo, Sonia, Bertorelle, Roberta, Sacchetto, Valeria, Pilotto, Giorgia, Basso, Giuseppe, Zanovello, Paola, Amadori, Alberto, Tosello, Valeria

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Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming von Valmori, Danila, Souleimanian, Naira E, Tosello, Valeria, Bhardwaj, Nina, Adams, Sylvia, O'Neill, David, Pavlick, Anna, Escalon, Juliet B, Cruz, Crystal M, Angiulli, Angelica, Angiulli, Francesca, Mears, Gregory, Vogel, Susan M, Pan, Linda, Jungbluth, Achim A, Hoffmann, Eric W, Venhaus, Ralph, Ritter, Gerd, Old, Lloyd J, Ayyoub, Maha

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Implementation of Next Generation Sequencing-Based Liquid Biopsy for Clinical Molecular Diagnostics in Non-Small Cell Lung Cancer (NSCLC) Patients von Zulato, Elisabetta, Tosello, Valeria, Nardo, Giorgia, Bonanno, Laura, Del Bianco, Paola, Indraccolo, Stefano

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miR-22-3p Negatively Affects Tumor Progression in T-Cell Acute Lymphoblastic Leukemia von Saccomani, Valentina, Grassi, Angela, Piovan, Erich, Bongiovanni, Deborah, Di Martino, Ludovica, Minuzzo, Sonia, Tosello, Valeria, Zanovello, Paola

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Absence of Biallelic TCRγ Deletion Predicts Early Treatment Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia von GUTIERREZ, Alejandro, DAHLBERG, Suzanne E, BOROWITZ, Michael J, LOH, Mignon L, FERRANDO, Adolfo A, WINTER, Stuart S, MULLIGHAN, Charles G, SILVERMAN, Lewis B, CHIN, Lynda, HUNGER, Stephen P, SALLAN, Stephen E, LOOK, A. Thomas, NEUBERG, Donna S, JIANHUA ZHANG, GREBLIUNAITE, Ruta, SANDA, Takaomi, PROTOPOPOV, Alexei, TOSELLO, Valeria, KUTOK, Jeffery, LARSON, Richard S

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Interruption of Tumor Dormancy by a Transient Angiogenic Burst within the Tumor Microenvironment von Indraccolo, Stefano, Stievano, Laura, Minuzzo, Sonia, Tosello, Valeria, Esposito, Giovanni, Piovan, Erich, Zamarchi, Rita, Chieco-Bianchi, Luigi, Amadori, Alberto

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A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia von Tosello, Valeria, Milani, Gloria, Martines, Annalisa, Macri, Nadia, Van Loocke, Wouder, Matthijssens, Filip, Buldini, Barbara, Minuzzo, Sonia, Bongiovanni, Deborah, Schumacher, Richard Fabian, Amadori, Alberto, Van Vlierberghe, Pieter, Piovan, Erich

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Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia von Herranz, Daniel, Ambesi-Impiombato, Alberto, Sudderth, Jessica, Sánchez-Martín, Marta, Belver, Laura, Tosello, Valeria, Xu, Luyao, Wendorff, Agnieszka A, Castillo, Mireia, Haydu, J Erika, Márquez, Javier, Matés, José M, Kung, Andrew L, Rayport, Stephen, Cordon-Cardo, Carlos, DeBerardinis, Ralph J, Ferrando, Adolfo A

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γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia von Ferrando, Adolfo, Real, Pedro J, Tosello, Valeria, Palomero, Teresa, Castillo, Mireia, Hernando, Eva, de Stanchina, Elisa, Sulis, Maria Luisa, Barnes, Kelly, Sawai, Catherine, Homminga, Irene, Meijerink, Jules, Aifantis, Iannis, Basso, Giuseppe, Cordon-Cardo, Carlos, Ai, Walden

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