Translational Implications for Off-the-shelf Immune Cells Expressing Chimeric Antigen Receptors von Torikai, Hiroki, Cooper, Laurence JN

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Toward eliminating HLA class I expression to generate universal cells from allogeneic donors von Torikai, Hiroki, Reik, Andreas, Soldner, Frank, Warren, Edus H., Yuen, Carrie, Zhou, Yuanyue, Crossland, Denise L., Huls, Helen, Littman, Nicholas, Zhang, Ziying, Tykodi, Scott S., Kebriaei, Partow, Lee, Dean A., Miller, Jeffrey C., Rebar, Edward J., Holmes, Michael C., Jaenisch, Rudolf, Champlin, Richard E., Gregory, Philip D., Cooper, Laurence J.N.

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Redirecting Specificity of T cells Using the Sleeping Beauty System to Express Chimeric Antigen Receptors by Mix-and-Matching of VL and VH Domains Targeting CD123+ Tumors von Thokala, Radhika, Olivares, Simon, Mi, Tiejuan, Maiti, Sourindra, Deniger, Drew, Huls, Helen, Torikai, Hiroki, Singh, Harjeet, Champlin, Richard E, Laskowski, Tamara, McNamara, George, Cooper, Laurence J N

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Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering von Zong, Shan, Mi, Tiejuan, Flores, 2nd, Leo G, Alpert, Amir, Olivares, Simon, Patel, Krina, Maiti, Sourindra, Mcnamara, George, Cooper, Laurence J N, Torikai, Hiroki

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Autophagy creates a CTL epitope that mimics tumor-associated antigens von Demachi-Okamura, Ayako, Torikai, Hiroki, Akatsuka, Yoshiki, Miyoshi, Hiroyuki, Yoshimori, Tamotsu, Kuzushima, Kiyotaka

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Alternative splicing due to an intronic SNP in HMSD generates a novel minor histocompatibility antigen von Kawase, Takakazu, Akatsuka, Yoshiki, Torikai, Hiroki, Morishima, Satoko, Oka, Akira, Tsujimura, Akane, Miyazaki, Mikinori, Tsujimura, Kunio, Miyamura, Koichi, Ogawa, Seishi, Inoko, Hidetoshi, Morishima, Yasuo, Kodera, Yoshihisa, Kuzushima, Kiyotaka, Takahashi, Toshitada

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HapMap scanning of novel human minor histocompatibility antigens von Kamei, Michi, Nannya, Yasuhito, Torikai, Hiroki, Kawase, Takakazu, Taura, Kenjiro, Inamoto, Yoshihiro, Takahashi, Taro, Yazaki, Makoto, Morishima, Satoko, Tsujimura, Kunio, Miyamura, Koichi, Ito, Tetsuya, Togari, Hajime, Riddell, Stanley R., Kodera, Yoshihisa, Morishima, Yasuo, Takahashi, Toshitada, Kuzushima, Kiyotaka, Ogawa, Seishi, Akatsuka, Yoshiki

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Mismatched human leukocyte antigen class II‐restricted CD8+ cytotoxic T cells may mediate selective graft‐versus‐leukemia effects following allogeneic hematopoietic cell transplant... von Hirosawa, Tomoya, Torikai, Hiroki, Yanagisawa, Mayumi, Kamei, Michi, Imahashi, Nobuhiko, Demachi‐Okamura, Ayako, Tanimoto, Miyoko, Shiraishi, Keiko, Ito, Mamoru, Miyamura, Koichi, Shibata, Kiyosumi, Kikkawa, Fumitaka, Morishima, Yasuo, Takahashi, Toshitada, Emi, Nobuhiko, Kuzushima, Kiyotaka, Akatsuka, Yoshiki

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Aberrant expression of BCL2A1-restricted minor histocompatibility antigens in melanoma cells: application for allogeneic transplantation von Torikai, Hiroki, Akatsuka, Yoshiki, Yatabe, Yasushi, Morishima, Yasuo, Kodera, Yoshihisa, Kuzushima, Kiyotaka, Takahashi, Toshitada

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Histiocytic sarcoma of the spleen: case report of asymptomatic onset of thrombocytopenia and complex imaging features von Kobayashi, Shinichi, Kimura, Fumihiko, Hama, Yukihiro, Ogura, Kazuto, Torikai, Hiroki, Kobayashi, Ayako, Ikeda, Takashi, Sato, Ken, Aida, Shinsuke, Kosuda, Shigeru, Motoyoshi, Kazuo

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CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo von Tian, Gengwen, Courtney, Amy N, Jena, Bipulendu, Heczey, Andras, Liu, Daofeng, Marinova, Ekaterina, Guo, Linjie, Xu, Xin, Torikai, Hiroki, Mo, Qianxing, Dotti, Gianpietro, Cooper, Laurence J, Metelitsa, Leonid S

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A Novel HLA-A3303-Restricted Minor Histocompatibility Antigen Encoded by an Unconventional Open Reading Frame of Human TMSB4Y Gene von Torikai, Hiroki, Akatsuka, Yoshiki, Miyazaki, Mikinori, Warren, Edus H., III, Oba, Taku, Tsujimura, Kunio, Motoyoshi, Kazuo, Morishima, Yasuo, Kodera, Yoshihisa, Kuzushima, Kiyotaka, Takahashi, Toshitada

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CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo von Tian, Gengwen, Courtney, Amy N., Jena, Bipulendu, Heczey, Andras, Liu, Daofeng, Marinova, Ekaterina, Guo, Linjie, Xu, Xin, Torikai, Hiroki, Mo, Qianxing, Dotti, Gianpietro, Cooper, Laurence J., Metelitsa, Leonid S.

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A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR von Torikai, Hiroki, Reik, Andreas, Liu, Pei-Qi, Zhou, Yuanyue, Zhang, Ling, Maiti, Sourindra, Huls, Helen, Miller, Jeffrey C., Kebriaei, Partow, Rabinovitch, Brian, Lee, Dean A., Champlin, Richard E., Bonini, Chiara, Naldini, Luigi, Rebar, Edward J., Gregory, Philip D., Holmes, Michael C., Cooper, Laurence J.N.

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Personalization of T-Cell Therapy Using a High-Throughput Platform to Identify Tumor-Specific T-Cell Receptors von Zong, Shan, Cooper, Laurence J.N., McNamara, George T, Torikai, Hiroki

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Adoptive T-Cell Therapy with TCL1-Specific TCR for B-Cell Lymphomas von Weng, Jinsheng, Moriarty, Kelsey, Pan, Yong, MA, Man Chun John, Mathur, Rohit, Zhang, Zheng, Torikai, Hiroki, Maiti, Sourindra N, Chu, Fuliang, Cheng, Xiaoyun, Karri, Swathi, Medapalli, Deepshika, Cooper, Laurence J N, Davis, R. Eric, Neelapu, Sattva S.

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Abstract 2566: A TCL1-specific T-cell receptor redirects T cells against B-cell lymphomas and non-hematological tumors von Weng, Jinsheng, Moriarty, Kelsey E., Pan, Yong, Baio, Flavio Egidio, Wang, Hua, Torikai, Hiroki, Maiti, Sourindra N., Chu, Fuliang, Cheng, Xiaoyun, Karri, Swathi, Medapalli, Deepshika, Cooper, Laurence J. N., Neelapu, Sattva S.

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Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application von Torikai, Hiroki, Mi, Tiejuan, Gragert, Loren, Maiers, Martin, Najjar, Amer, Ang, Sonny, Maiti, Sourindra, Dai, Jianliang, Switzer, Kirsten C., Huls, Helen, Dulay, Gladys P., Reik, Andreas, Rebar, Edward J., Holmes, Michael C., Gregory, Philip D., Champlin, Richard E., Shpall, Elizabeth J., Cooper, Laurence J. N.

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Sleeping beauty system to redirect T-cell specificity for human applications von Maiti, Sourindra N, Huls, Helen, Singh, Harjeet, Dawson, Margaret, Figliola, Matthew, Olivares, Simon, Rao, Pullavathi, Zhao, Yi Jue, Multani, Asha, Yang, Ge, Zhang, Ling, Crossland, Denise, Ang, Sonny, Torikai, Hiroki, Rabinovich, Brian, Lee, Dean A, Kebriaei, Partow, Hackett, Perry, Champlin, Richard E, Cooper, Laurence J N

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Redirecting T-Cell Specificity to EGFR Using mRNA to Self-limit Expression of Chimeric Antigen Receptor von Caruso, Hillary G, Torikai, Hiroki, Zhang, Ling, Maiti, Sourindra, Dai, Jianliang, Do, Kim-Anh, Singh, Harjeet, Huls, Helen, Lee, Dean A, Champlin, Richard E, Heimberger, Amy B, Cooper, Laurence J N

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