Small molecule immuno-oncology therapeutic agents von Toogood, Peter L.

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Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Where will the drugs come from? von Toogood, Peter L., Clauw, Daniel J., Phadke, Sameer, Hoffman, David

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Sterol metabolism controls T(H)17 differentiation by generating endogenous RORγ agonists von Hu, Xiao, Wang, Yahong, Hao, Ling-Yang, Liu, Xikui, Lesch, Chuck A, Sanchez, Brian M, Wendling, Jay M, Morgan, Rodney W, Aicher, Tom D, Carter, Laura L, Toogood, Peter L, Glick, Gary D

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Inhibition of Protein−Protein Association by Small Molecules:  Approaches and Progress von Toogood, Peter L

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Sterol metabolism controls TH17 differentiation by generating endogenous RORγ agonists von Hu, Xiao, Wang, Yahong, Hao, Ling-Yang, Liu, Xikui, Lesch, Chuck A, Sanchez, Brian M, Wendling, Jay M, Morgan, Rodney W, Aicher, Tom D, Carter, Laura L, Toogood, Peter L, Glick, Gary D

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Identification of a Selective Pyruvate Dehydrogenase Kinase 1 (PDHK1) Chemical Probe by Virtual Screening von Baber, Mason A., Gough, Mya D., Yeomans, Larisa, Giesler, Kyle, Muzzarelli, Kendall, Chen, Chih-Jung, Assar, Zahra, Toogood, Peter L.

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Mitochondrial drugs von Toogood, Peter L

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Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts von Fry, David W, Harvey, Patricia J, Keller, Paul R, Elliott, William L, Meade, Maryanne, Trachet, Erin, Albassam, Mudher, Zheng, XianXian, Leopold, Wilbur R, Pryer, Nancy K, Toogood, Peter L

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COVID-19: Living through Another Pandemic von Osman, Essam Eldin A, Toogood, Peter L, Neamati, Nouri

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Discovery of a Potent and Selective Inhibitor of Cyclin-Dependent Kinase 4/6 von Toogood, Peter L, Harvey, Patricia J, Repine, Joseph T, Sheehan, Derek J, VanderWel, Scott N, Zhou, Hairong, Keller, Paul R, McNamara, Dennis J, Sherry, Debra, Zhu, Tong, Brodfuehrer, Joanne, Choi, Chung, Barvian, Mark R, Fry, David W

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Synthesis of (−)-PNU-286607 by Asymmetric Cyclization of Alkylidene Barbiturates von Ruble, J. Craig, Hurd, Alexander R, Johnson, Timothy A, Sherry, Debra A, Barbachyn, Michael R, Toogood, Peter L, Bundy, Gordon L, Graber, David R, Kamilar, Gregg M

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A novel therapeutic combination using PD 0332991 and bortezomib: study in the 5T33MM myeloma model von Menu, Eline, Garcia, Josefina, Huang, Xiangao, Di Liberto, Maurizio, Toogood, Peter L, Chen, Isan, Vanderkerken, Karin, Chen-Kiang, Selina

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Discovery of LYC-55716: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor‑γ (RORγ) Agonist for Use in Treating Cancer von Aicher, Thomas D, Van Huis, Chad A, Hurd, Alexander R, Skalitzky, Donald J, Taylor, Clarke B, Beleh, Omar M, Glick, Gary, Toogood, Peter L, Yang, Bing, Zheng, Tao, Huo, Changxin, Gao, Jie, Qiao, Chenxi, Tian, Xiaolong, Zhang, Junping, Demock, Kellie, Hao, Ling-Yang, Lesch, Charles A, Morgan, Rodney W, Moisan, Jacques, Wang, Yahong, Scatina, JoAnn, Paulos, Chrystal M, Zou, Weiping, Carter, Laura L, Hu, Xiao

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A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6 von BAUGHN, Linda B, DI LIBERTO, Maurizio, CHEN-KIANG, Selina, KAIDA WU, TOOGOOD, Peter L, LOUIE, Tracey, GOTTSCHALK, Rachel, NIESVIZKY, Ruben, CHO, Hearn, ELY, Scott, MOORE, Malcolm A. S

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Synthetic RORγ agonists regulate multiple pathways to enhance antitumor immunity von Hu, Xiao, Liu, Xikui, Moisan, Jacques, Wang, Yahong, Lesch, Charles A., Spooner, Chauncey, Morgan, Rodney W., Zawidzka, Elizabeth M., Mertz, David, Bousley, Dick, Majchrzak, Kinga, Kryczek, Ilona, Taylor, Clarke, Van Huis, Chad, Skalitzky, Don, Hurd, Alexander, Aicher, Thomas D., Toogood, Peter L., Glick, Gary D., Paulos, Chrystal M., Zou, Weiping, Carter, Laura L.

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Identifying selective PDHK inhibitors using coupled tensor matrix completion and experimental validation von Rajaei, Flora, Toogood, Peter, Jacob, Renju, Baber, Mason, Gough, Mya, Derksen, Harm, Wittrup, Emily, Najarian, Kayvan

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Cyclin-dependent kinase inhibitors for treating cancer von Toogood, Peter L.

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Pyrido[2,3-d]pyrimidin-7-ones as Specific Inhibitors of Cyclin-Dependent Kinase 4 von VanderWel, Scott N, Harvey, Patricia J, McNamara, Dennis J, Repine, Joseph T, Keller, Paul R, Quin, John, Booth, R. John, Elliott, William L, Dobrusin, Ellen M, Fry, David W, Toogood, Peter L

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Progress toward the development of agents to modulate the cell cycle von Toogood, Peter L

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A Short and Efficient Synthesis of l-5,5,5,5‘,5‘,5‘-hexafluoroleucine from N-Cbz-l-Serine von Anderson, James T, Toogood, Peter L, Marsh, E. Neil G

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