Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING von Siu, Tony, Altman, Michael D, Baltus, Gretchen A, Childers, Matthew, Ellis, J. Michael, Gunaydin, Hakan, Hatch, Harold, Ho, Thu, Jewell, James, Lacey, Brian M, Lesburg, Charles A, Pan, Bo-Sheng, Sauvagnat, Berengere, Schroeder, Gottfried K, Xu, Serena

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The discovery of tricyclic pyridone JAK2 inhibitors. Part 1: Hit to lead von Siu, Tony, Kozina, Ekaterina S., Jung, Joon, Rosenstein, Craig, Mathur, Anjili, Altman, Michael D., Chan, Grace, Xu, Lin, Bachman, Eric, Mo, Jan-Rung, Bouthillette, Melaney, Rush, Thomas, Dinsmore, Christopher J., Marshall, C. Gary, Young, Jonathan R.

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Efficacy and safety of modified Xiao-Feng Powder in the treatment of chronic urticaria: protocol of a randomized double-blind placebo-controlled study von Hung, Hing Yu, Song, Tianhe, Loo, Steven King Fan, Chan, Kam Leung, Ching, Jessica Yuet Ling, Sum, Chi Him, Lo, Louis Cho Wing, Chia, Sarah Chon Pin, Ho, Ray Tin Muk, Cheong, Pui Kuan, Siu, Tony Hon Chung, Leung, Ka Chun, Lin, Zhi-Xiu

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Gadolinium and Polythiophene Functionalized Polyurea Polymer Dots as Fluoro-Magnetic Nanoprobes von Karabacak, Soner, Palaniappan, Alagappan, Tony, Tsang Siu Hon, Edwin, Teo Hang Tong, Gulyás, Balázs, Padmanabhan, Parasuraman, Yildiz, Ümit Hakan

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Diagnostic check for heavy tail in linear time series von Wong, Tony Siu Tung

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Characterization of RNA driven structural changes in full length RIG-I leading to its agonism or antagonism von Sikorska, Justyna, Hou, Yan, Chiurazzi, Paul, Siu, Tony, Baltus, Gretchen A, Sheth, Payal, McLaren, David G, Truong, Quang, Parish, Craig A, Wyss, Daniel F

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Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer von Chang, Wonsuk, Altman, Michael D, Lesburg, Charles A, Perera, Samanthi A, Piesvaux, Jennifer A, Schroeder, Gottfried K, Wyss, Daniel F, Cemerski, Saso, Chen, Yiping, DiNunzio, Edward, Haidle, Andrew M, Ho, Thu, Kariv, Ilona, Knemeyer, Ian, Kopinja, Johnny E, Lacey, Brian M, Laskey, Jason, Lim, Jongwon, Long, Brian J, Ma, Yanhong, Maddess, Matthew L, Pan, Bo-Sheng, Presland, Jeremy P, Spooner, Edward, Steinhuebel, Dietrich, Truong, Quang, Zhang, Zhibo, Fu, Jianmin, Addona, George H, Northrup, Alan B, Parmee, Emma, Tata, James R, Bennett, David Jonathan, Cumming, Jared N, Siu, Tony, Trotter, B. Wesley

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Test for homogeneity in gamma mixture models using likelihood ratio von Wong, Tony Siu Tung, Li, Wai Keung

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The Discovery of 3‑((4-Chloro-3-methoxyphenyl)amino)-1-((3R,4S)‑4-cyanotetrahydro‑2H‑pyran-3-yl)‑1H‑pyrazole-4-carboxamide, a Highly Ligand Efficient and Efficacious Janus Kinase 1... von Siu, Tony, Brubaker, Jason, Fuller, Peter, Torres, Luis, Zeng, Hongbo, Close, Joshua, Mampreian, Dawn M., Shi, Feng, Liu, Duan, Fradera, Xavier, Johnson, Kevin, Bays, Nathan, Kadic, Elma, He, Fang, Goldenblatt, Peter, Shaffer, Lynsey, Patel, Sangita B., Lesburg, Charles A., Alpert, Carla, Dorosh, Lauren, Deshmukh, Sujal V., Yu, Hongshi, Klappenbach, Joel, Elwood, Fiona, Dinsmore, Christopher J., Fernandez, Rafael, Moy, Lily, Young, Jonathan R.

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Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitors von Simov, Vladimir, Deshmukh, Sujal V., Dinsmore, Christopher J., Elwood, Fiona, Fernandez, Rafael B., Garcia, Yudith, Gibeau, Craig, Gunaydin, Hakan, Jung, Joon, Katz, Jason D., Kraybill, Brian, Lapointe, Blair, Patel, Sangita B., Siu, Tony, Su, Hua, Young, Jonathan R.

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A THRESHOLD APPROACH FOR PEAKS-OVER-THRESHOLD MODELING USING MAXIMUM PRODUCT OF SPACINGS von Wong, Tony Siu Tung, Li, Wai Keung

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Allosteric inhibitors of Akt1 and Akt2: Discovery of [1,2,4]triazolo[3,4-f][1,6]naphthyridines with potent and balanced activity von Li, Yiwei, Liang, Jun, Siu, Tony, Hu, Essa, Rossi, Michael A., Barnett, Stanley F., Defeo-Jones, Deborah, Jones, Raymond E., Robinson, Ronald G., Leander, Karen, Huber, Hans E., Mittal, Sachin, Cosford, Nicholas, Prasit, Peppi

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Studies Directed toward the Total Synthesis of Lactonamycin: Control of the Sense of Cycloaddition of a Quinone through Directed Intramolecular Catalysis von Cox, Christopher D., Siu, Tony, Danishefsky, Samuel J.

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Total Synthesis of Lactonamycinone von Siu, Tony, Cox, Christopher D., Danishefsky, Samuel J.

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The design and synthesis of potent and cell-active allosteric dual Akt 1 and 2 inhibitors devoid of hERG activity von Siu, Tony, Li, Yiwei, Nagasawa, Johnny, Liang, Jun, Tehrani, Lida, Chua, Peter, Jones, Raymond E., Defeo-Jones, Deborah, Barnett, Stanley F., Robinson, Ronald G.

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Discovery of potent and cell-active allosteric dual Akt 1 and 2 inhibitors von Siu, Tony, Liang, Jun, Arruda, Jeannie, Li, Yiwei, Jones, Raymond E., Defeo-Jones, Deborah, Barnett, Stanley F., Robinson, Ronald G.

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Substituted RIG-I agonists: compositions and methods thereof von Chang, Wonsuk, Wang, Hongwu, Siu, Tony, Truong, Quang T, Wassermann, Anne Mai, Parish, Craig A

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Heteroaryl Compounds as Ligand Directed Degraders of IRAK4 von Meng, Yilin, Ellis, Michael, Gormisky, Paul, Siu, Tony, Hager, Harry, Hu, Lingbowei, Davies, Geraint, Rasmusson, Timothy, van der Mei, Farid, Ma, Rulin

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Oxo-tetrahydro-isoquinoline carboxylic acids as STING inhibitors von Siu, Tony, Altman, Michael D, Childers, Matthew L, Jewell, James P, Lesburg, Charles A

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CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS von CUMMING, Jared, N, TROTTER, Benjamin Wesley, LU, Min, CHILDERS, Matthew Lloyd, OTTE, Ryan, D, CHANG, Wonsuk, HAIDLE, Andrew Marc, NORTHRUP, Alan, B, ANDRESEN, Brian, HENDERSON, Timothy, J, JEWELL, James, P, TRUONG, Quang, T, ALTMAN, Michael, D, SIU, Tony

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