Drug–Target Kinetics in Drug Discovery von Tonge, Peter J

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Drug–target residence time: critical information for lead optimization von Lu, Hao, Tonge, Peter J

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Pharmacokinetic–pharmacodynamic models that incorporate drug–target binding kinetics von Daryaee, Fereidoon, Tonge, Peter J

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Photophysics of the Blue Light Using Flavin Domain von Lukacs, Andras, Tonge, Peter J, Meech, Stephen R

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Inhibitors of FabI, an Enzyme Drug Target in the Bacterial Fatty Acid Biosynthesis Pathway von Lu, Hao, Tonge, Peter J

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Quantifying the Interactions between Biomolecules: Guidelines for Assay Design and Data Analysis von Tonge, Peter J

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Drug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosis von Kinnings, Sarah L, Liu, Nina, Buchmeier, Nancy, Tonge, Peter J, Xie, Lei, Bourne, Philip E

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Elucidating signal transduction pathway in light-activated adenylyl cyclase using unnatural amino acid mutagenesis von Jewlikar, Samruddhi S., Tolentino, Jinnette, Ali, Madeeha, Tonge, Peter J.

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Staphylococcus aureus FabI: Inhibition, Substrate Recognition, and Potential Implications for In Vivo Essentiality von Schiebel, Johannes, Chang, Andrew, Lu, Hao, Baxter, Michael V., Tonge, Peter J., Kisker, Caroline

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Structure–kinetic relationships that control the residence time of drug–target complexes: insights from molecular structure and dynamics von Lu, Hao, Iuliano, James N, Tonge, Peter J

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The Isoniazid-NAD Adduct Is a Slow, Tight-Binding Inhibitor of InhA, the Mycobacterium tuberculosis Enoyl Reductase: Adduct Affinity and Drug Resistance von Rawat, Richa, Whitty, Adrian, Tonge, Peter J.

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Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas von Agnihotri, Sameer, Suppiah, Suganth, Tonge, Peter D., Jalali, Shahrzad, Danesh, Arnavaz, Bruce, Jeffery P., Mamatjan, Yasin, Klironomos, George, Gonen, Lior, Au, Karolyn, Mansouri, Sheila, Karimi, Sharin, Sahm, Felix, von Deimling, Andreas, Taylor, Michael D., Laperriere, Normand J., Pugh, Trevor J., Aldape, Kenneth D., Zadeh, Gelareh

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High Accuracy Prediction of PROTAC Complex Structures von Ignatov, Mikhail, Jindal, Akhil, Kotelnikov, Sergei, Beglov, Dmitri, Posternak, Ganna, Tang, Xiaojing, Maisonneuve, Pierre, Poda, Gennady, Batey, Robert A., Sicheri, Frank, Whitty, Adrian, Tonge, Peter J., Vajda, Sandor, Kozakov, Dima

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A Machine Learning-Based Method To Improve Docking Scoring Functions and Its Application to Drug Repurposing von Kinnings, Sarah L, Liu, Nina, Tonge, Peter J, Jackson, Richard M, Xie, Lei, Bourne, Philip E

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Functional dynamics of a single tryptophan residue in a BLUF protein revealed by fluorescence spectroscopy von Karadi, Kristof, Kapetanaki, Sofia M., Raics, Katalin, Pecsi, Ildiko, Kapronczai, Robert, Fekete, Zsuzsanna, Iuliano, James N., Collado, Jinnette Tolentino, Gil, Agnieszka A., Orban, Jozsef, Nyitrai, Miklos, Greetham, Greg M., Vos, Marten H., Tonge, Peter J., Meech, Stephen R., Lukacs, Andras

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Chemically controlled aggregation of pluripotent stem cells von Lipsitz, Yonatan Y., Tonge, Peter D., Zandstra, Peter W.

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Editorial overview: Next generation therapeutics von Whitty, Adrian, Tonge, Peter J

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Synthesis and Biological Evaluation of Fluorine-18 and Deuterium Labeled l‑Fluoroalanines as Positron Emission Tomography Imaging Agents for Cancer Detection von Li, Kaixuan, Gilberti, Alexa L., Marden, Jocelyn A., Akula, Hari K., Pollard, Alyssa C., Guo, Shuwen, Hu, Bao, Tonge, Peter J., Qu, Wenchao

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A Slow, Tight Binding Inhibitor of InhA, the Enoyl-Acyl Carrier Protein Reductase from Mycobacterium tuberculosis von Luckner, Sylvia R., Liu, Nina, am Ende, Christopher W., Tonge, Peter J., Kisker, Caroline

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Biological Evaluation of d‑[18F]Fluoroalanine and d‑[18F]Fluoroalanine‑d 3 as Positron Emission Tomography Imaging Tracers for Bacterial Infection von Li, Kaixuan, Tolentino Collado, Jinnette, Marden, Jocelyn A., Pollard, Alyssa C., Guo, Shuwen, Tonge, Peter J., Qu, Wenchao

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