Synthesis, Pharmacological Characterization, and Molecular Modeling of Heterobicyclic Amino Acids Related to (+)-2-Aminobicyclo[3.1.0]hexane- 2,6-dicarboxylic Acid (LY354740):  Ide... von Monn, James A, Valli, Matthew J, Massey, Steven M, Hansen, Marvin M, Kress, Thomas J, Wepsiec, James P, Harkness, Allen R, Grutsch, John L, Wright, Rebecca A, Johnson, Bryan G, Andis, Sherri L, Kingston, Ann, Tomlinson, Rosemarie, Lewis, Richard, Griffey, Kelly R, Tizzano, Joseph P, Schoepp, Darryle D

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Naphthyl piperazines with dual activity as 5-HT1D antagonists and 5-HT reuptake inhibitors von BUENO, Ana B, GILMORE, Jeremy, TIMMS, Graham, TOMLINSON, Rosemarie, WALLACE, Louise, WALTON, Leslie, BOOT, John, BROADMORE, Richard, COOPER, Jane, FINDLAY, Jeremy, HAYHURST, Lorna, MARCOS, Alicia, MONTERO, Carlos, MITCHELL, Stephen

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Novel selective and potent 5-HT reuptake inhibitors with 5-HT1D antagonist activity: chemistry and pharmacological evaluation of a series of thienopyran derivatives von TORRADO, Alicia, LAMAS, Carlos, BROADMORE, Richard, TOMLINSON, Rosemarie, AGEJAS, Javier, JIMENEZ, Alma, DIAZ, Nuria, GILMORE, Jeremy, BOOT, John, FINDLAY, Jeremy, HAYHURST, Lorna, WALLACE, Louise

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Naphthyl piperazines with dual activity as 5-HT sub(1D) antagonists and 5- HT reuptake inhibitors von Bueno, Ana B, Gilmore, Jeremy, Boot, John, Broadmore, Richard, Cooper, Jane, Findlay, Jeremy, Hayhurst, Lorna, Marcos, Alicia, Montero, Carlos, Mitchell, Stephen, Timms, Graham, Tomlinson, Rosemarie, Wallace, Louise, Walton, Leslie

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Inhibition of group I metabotropic glutamate receptor responses in vivo in rats by a new generation of carboxyphenylglycine-like amino acid antagonists von Kingston, Ann E, Griffey, Kelly, Johnson, Michael P, Chamberlain, Mary-Jo, Kelly, Gerald, Tomlinson, Rosemarie, Wright, Rebecca A, Johnson, Bryan G, Schoepp, Darryle D, Harris, John R, Clark, Barry P, Baker, Richard S, Tizzano, Joseph P

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Naphthyl piperazines with dual activity as 5-HT 1D antagonists and 5-HT reuptake inhibitors von Bueno, Ana B., Gilmore, Jeremy, Boot, John, Broadmore, Richard, Cooper, Jane, Findlay, Jeremy, Hayhurst, Lorna, Marcos, Alicia, Montero, Carlos, Mitchell, Stephen, Timms, Graham, Tomlinson, Rosemarie, Wallace, Louise, Walton, Leslie

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Novel selective and potent 5-HT reuptake inhibitors with 5-HT 1D antagonist activity: chemistry and pharmacological evaluation of a series of thienopyran derivatives von Torrado, Alicia, Lamas, Carlos, Agejas, Javier, Jiménez, Alma, Dı́az, Nuria, Gilmore, Jeremy, Boot, John, Findlay, Jeremy, Hayhurst, Lorna, Wallace, Louise, Broadmore, Richard, Tomlinson, Rosemarie

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In vitro activity of LY393558, an inhibitor of the 5-hydroxytryptamine transporter with 5-HT1B/1D/2 receptor antagonist properties von PULLAR, Ian A, BOOT, John R, TOMLINSON, Rosemarie, WEDLEY, Susan, CARNEY, Stephen L, COHEN, Marlene L, COLVIN, Ellen M, CONWAY, Richard G, HARDY, Clare H. L, LUCAITES, Virginia L, NELSON, David L, SCHENCK, Kathryn W

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In vitro activity of LY393558, an inhibitor of the 5-hydroxytryptamine transporter with 5-HT 1B/1D/2 receptor antagonist properties von Pullar, Ian A, Boot, John R, Carney, Stephen L, Cohen, Marlene L, Colvin, Ellen M, Conway, Richard G, Hardy, Clare H.L, Lucaites, Virginia L, Nelson, David L, Schenck, Kathryn W, Tomlinson, Rosemarie, Wedley, Susan

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Synthesis and metabotropic glutamate receptor antagonist activity of N 1-substituted analogs of 2 R,4 R-4-aminopyrrolidine-2,4-dicarboxylic acid von Valli, Matthew J, Schoepp, Darryle D, Wright, Rebecca A, Johnson, Bryan G, Kingston, Ann E, Tomlinson, Rosemarie, Monn, James A

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Synthesis and metabotropic glutamate receptor antagonist activity of N1-substituted analogs of 2R, 4R-4-aminopyrrolidine-2,4-dicarboxylic acid von VALLI, M. J, SCHOEPP, D. D, WRIGHT, R. A, JOHNSON, B. G, KINGSTON, A. E, TOMLINSON, R, MONN, J. A

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Anthraquinones related to rhein inhibit glucose uptake into chondrocytes. A mechanism for anti-osteoarthritis drugs? von Carney, Stephen L., Broadmore, Richard J., Tomlinson, Rosemarie, Kingston, Ann, Gallagher, Peter T., Owton, W.Martin, Miles, Martin V., Brunavs, Michael, Smith, Colin W., Hicks, Terry A., Dobson, David R., Steggles, David J., Ambler, Samantha J., Halliday, Kelly A.

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Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas von Palles, Claire, Cazier, Jean-Baptiste, Howarth, Kimberley M, Domingo, Enric, Jones, Angela M, Broderick, Peter, Kemp, Zoe, Spain, Sarah L, Guarino, Estrella, Salguero, Israel, Sherborne, Amy, Chubb, Daniel, Carvajal-Carmona, Luis G, Ma, Yusanne, Kaur, Kulvinder, Dobbins, Sara, Barclay, Ella, Gorman, Maggie, Martin, Lynn, Kovac, Michal B, Humphray, Sean, Lucassen, Anneke, Holmes, Christopher C, Bentley, David, Donnelly, Peter, Taylor, Jenny, Petridis, Christos, Roylance, Rebecca, Sawyer, Elinor J, Kerr, David J, Clark, Susan, Grimes, Jonathan, Kearsey, Stephen E, Thomas, Huw J W, McVean, Gilean, Houlston, Richard S, Tomlinson, Ian

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Liver Environment and HCV Replication Affect Human T-Cell Phenotype and Expression of Inhibitory Receptors von Kroy, Daniela C, Ciuffreda, Donatella, Cooperrider, Jennifer H, Tomlinson, Michelle, Hauck, Garrett D, Aneja, Jasneet, Berger, Christoph, Wolski, David, Carrington, Mary, Wherry, E. John, Chung, Raymond T, Tanabe, Kenneth K, Elias, Nahel, Freeman, Gordon J, de Kruyff, Rosemarie H, Misdraji, Joseph, Kim, Arthur Y, Lauer, Georg M

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Clinical spectrum of individuals with pathogenic NF1 missense variants affecting p.Met1149, p.Arg1276, and p.Lys1423: genotype–phenotype study in neurofibromatosis type 1 von Koczkowska, Magdalena, Callens, Tom, Chen, Yunjia, Gomes, Alicia, Hicks, Alesha D., Sharp, Angela, Johns, Eric, Uhas, Kim Armfield, Armstrong, Linlea, Bosanko, Katherine Armstrong, Babovic‐Vuksanovic, Dusica, Baker, Laura, Basel, Donald G., Bennett, James T., Chambers, Chelsea, Clarkson, Lola K., Clementi, Maurizio, Cortés, Fanny M., Cunningham, Mitch, D'Agostino, M. Daniela, Delatycki, Martin B., Digilio, Maria C., Dosa, Laura, Esposito, Silvia, Fox, Stephanie, Freckmann, Mary‐Louise, Fauth, Christine, Giugliano, Teresa, Giustini, Sandra, Goetsch, Allison, Greenwood, Robert S., Griffis, Cristin, Gripp, Karen W., Gupta, Punita, Haan, Eric, Hachen, Rachel K., Haygarth, Tamara L., Hernández‐Chico, Concepción, Hodge, Katelyn, Hopkin, Robert J., Hudgins, Louanne, Janssens, Sandra, Keller, Kory, Kelly‐Mancuso, Geraldine, Kochhar, Aaina, Korf, Bruce R., Lewis, Andrea M., Liebelt, Jan, Lichty, Angie, Listernick, Robert H., Lyons, Michael J., Maystadt, Isabelle, Martinez Ojeda, Mayra, McDougall, Carey, McGregor, Lesley K., Melis, Daniela, Mendelsohn, Nancy, Nowaczyk, Malgorzata J.M., Ortenberg, June, Panzer, Karin, Pierpont, Mary Ella, Piluso, Giulio, Pinna, Valentina, Pivnick, Eniko K., Pond, Dinel A., Powell, Cynthia M., Rogers, Caleb, Ruhrman Shahar, Noa, Rutledge, S. Lane, Saletti, Veronica, Sandaradura, Sarah A., Schatz, Ulrich A., Scott, Daryl A., Sellars, Elizabeth A., Sheffer, Ruth, Siqveland, Elizabeth, Slopis, John M., Smith, Rosemarie, Spalice, Alberto, Stockton, David W., Streff, Haley, Theos, Amy, Tomlinson, Gail E., Tran, Grace, Trapane, Pamela L., Trevisson, Eva, Ullrich, Nicole J., Van den Ende, Jenneke, Schrier Vergano, Samantha A., Wallace, Stephanie E., Wangler, Michael F., Yohay, Kaleb H., Zackai, Elaine, Zonana, Jonathan, Claes, Kathleen B. M., Eoli, Marica, Wimmer, Katharina, De Luca, Alessandro, Legius, Eric, Messiaen, Ludwine M.

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Protecting Frontline Health Care Workers from COVID-19 with Hydroxychloroquine Pre-exposure Prophylaxis: A structured summary of a study protocol for a randomised placebo-controlle... von Wright, Julie K, Tan, Darrell H S, Walmsley, Sharon L, Hulme, Jennifer, O'Connor, Erin, Snider, Carolyn, Cheng, Ivy, Chan, Adrienne K, Borgundvaag, Bjug, McLeod, Shelley, Gollob, Michael H, Clarke, Rosemarie J, Dresser, Linda, Haji, Fatima, Mazzulli, Tony, Mubareka, Samira, Jüni, Peter, Lee, Dominic, Tomlinson, George, Kain, Kevin C, Landes, Megan

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Common genetic variants at the CRAC1 ( HMPS ) locus on chromosome 15q13.3 influence colorectal cancer risk von Tomlinson, Ian, Chandler, Ian, Tenesa, Albert, Farrington, Susan, Domingo, Enric, Martin, Lynn, Vijayakrishnan, Jayaram, Barclay, Ella, Houlston, Richard, Walther, Axel, Wood, Wendy, Gorman, Maggie, Heinimann, Karl, Broderick, Peter, Howarth, Kimberley, Thomas, Huw, Peto, Julian, Campbell, Harry, Webb, Emily, Sullivan, Kate, Penegar, Steven, Papaemmanuil, Elli, Kemp, Zoe, Kerr, David, Gray, Richard, Carvajal-Carmona, Luis, Cazier, Jean-Baptiste, Pittman, Alan, Rowan, Andrew, Lubbe, Steven, Jaeger, Emma, Dunlop, Malcolm, Spain, Sarah, Qureshi, Mobshra

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Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk von Dunlop, Malcolm G, Dobbins, Sara E, Farrington, Susan Mary, Jones, Angela M, Palles, Claire, Whiffin, Nicola, Tenesa, Albert, Spain, Sarah, Broderick, Peter, Ooi, Li-Yin, Domingo, Enric, Smillie, Claire, Henrion, Marc, Frampton, Matthew, Martin, Lynn, Grimes, Graeme, Gorman, Maggie, Semple, Colin, Ma, Yusanne P, Barclay, Ella, Prendergast, James, Cazier, Jean-Baptiste, Olver, Bianca, Penegar, Steven, Lubbe, Steven, Chander, Ian, Carvajal-Carmona, Luis G, Ballereau, Stephane, Lloyd, Amy, Vijayakrishnan, Jayaram, Zgaga, Lina, Rudan, Igor, Theodoratou, Evropi, Starr, John M, Deary, Ian, Kirac, Iva, Kovacević, Dujo, Aaltonen, Lauri A, Renkonen-Sinisalo, Laura, Mecklin, Jukka-Pekka, Matsuda, Koichi, Nakamura, Yusuke, Okada, Yukinori, Gallinger, Steven, Duggan, David J, Conti, David, Newcomb, Polly, Hopper, John, Jenkins, Mark A, Schumacher, Fredrick, Casey, Graham, Easton, Douglas, Shah, Mitul, Pharoah, Paul, Lindblom, Annika, Liu, Tao, Smith, Christopher G, West, Hannah, Cheadle, Jeremy P, Midgley, Rachel, Kerr, David J, Campbell, Harry, Tomlinson, Ian P, Houlston, Richard S

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Clinical spectrum of individuals with pathogenic N F1 missense variants affecting p.Met1149, p.Arg1276, and p.Lys1423: genotype–phenotype study in neurofibromatosis type 1 von Koczkowska, Magdalena, Callens, Tom, Chen, Yunjia, Gomes, Alicia, Hicks, Alesha D., Sharp, Angela, Johns, Eric, Uhas, Kim Armfield, Armstrong, Linlea, Bosanko, Katherine Armstrong, Babovic‐Vuksanovic, Dusica, Baker, Laura, Basel, Donald G., Bengala, Mario, Bennett, James T., Chambers, Chelsea, Clarkson, Lola K., Clementi, Maurizio, Cortés, Fanny M., Cunningham, Mitch, D'Agostino, M. Daniela, Delatycki, Martin B., Digilio, Maria C., Dosa, Laura, Esposito, Silvia, Fox, Stephanie, Freckmann, Mary‐Louise, Fauth, Christine, Giugliano, Teresa, Giustini, Sandra, Goetsch, Allison, Goldberg, Yael, Greenwood, Robert S., Griffis, Cristin, Gripp, Karen W., Gupta, Punita, Haan, Eric, Hachen, Rachel K., Haygarth, Tamara L., Hernández‐Chico, Concepción, Hodge, Katelyn, Hopkin, Robert J., Hudgins, Louanne, Janssens, Sandra, Keller, Kory, Kelly‐Mancuso, Geraldine, Kochhar, Aaina, Korf, Bruce R., Lewis, Andrea M., Liebelt, Jan, Lichty, Angie, Listernick, Robert H., Lyons, Michael J., Maystadt, Isabelle, Martinez Ojeda, Mayra, McDougall, Carey, McGregor, Lesley K., Melis, Daniela, Mendelsohn, Nancy, Nowaczyk, Malgorzata J.M., Ortenberg, June, Panzer, Karin, Pappas, John G., Pierpont, Mary Ella, Piluso, Giulio, Pinna, Valentina, Pivnick, Eniko K., Pond, Dinel A., Powell, Cynthia M., Rogers, Caleb, Ruhrman Shahar, Noa, Rutledge, S. Lane, Saletti, Veronica, Sandaradura, Sarah A., Santoro, Claudia, Schatz, Ulrich A., Schreiber, Allison, Scott, Daryl A., Sellars, Elizabeth A., Sheffer, Ruth, Siqveland, Elizabeth, Slopis, John M., Smith, Rosemarie, Spalice, Alberto, Stockton, David W., Streff, Haley, Theos, Amy, Tomlinson, Gail E., Tran, Grace, Trapane, Pamela L., Trevisson, Eva, Ullrich, Nicole J., Van den Ende, Jenneke, Schrier Vergano, Samantha A., Wallace, Stephanie E., Wangler, Michael F., Weaver, David D., Yohay, Kaleb H., Zackai, Elaine, Zonana, Jonathan

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Clinical spectrum of individuals with pathogenic NF1 missense variants affecting p.Met1149, p.Arg1276, and p.Lys1423: genotype-phenotype study in neurofibromatosis type 1 von Koczkowska, Magdalena, Callens, Tom, Chen, Yunjia, Gomes, Alicia, Hicks, Alesha D, Sharp, Angela, Johns, Eric, Uhas, Kim Armfield, Armstrong, Linlea, Bosanko, Katherine Armstrong, Babovic-Vuksanovic, Dusica, Baker, Laura, Basel, Donald G, Bengala, Mario, Bennett, James T, Chambers, Chelsea, Clarkson, Lola K, Clementi, Maurizio, Cortes, Fanny M, Cunningham, Mitch, D'Agostino, M. Daniela, Delatycki, Martin B, Digilio, Maria C, Dosa, Laura, Esposito, Silvia, Fox, Stephanie, Freckmann, Mary-Louise, Fauth, Christine, Giugliano, Teresa, Giustini, Sandra, Goetsch, Allison, Goldberg, Yael, Greenwood, Robert S, Griffis, Cristin, Gripp, Karen W, Gupta, Punita, Haan, Eric, Hachen, Rachel K, Haygarth, Tamara L, Hernandez-Chico, Concepcion, Hodge, Katelyn, Hopkin, Robert J, Hudgins, Louanne, Janssens, Sandra, Keller, Kory, Kelly-Mancuso, Geraldine, Kochhar, Aaina, Korf, Bruce R, Lewis, Andrea M, Liebelt, Jan, Lichty, Angie, Listernick, Robert H, Lyons, Michael J, Maystadt, Isabelle, Ojeda, Mayra Martinez, McDougall, Carey, McGregor, Lesley K, Melis, Daniela, Mendelsohn, Nancy, Nowaczyk, Malgorzata J.M, Ortenberg, June, Panzer, Karin, Pappas, John G, Pierpont, Mary Ella, Piluso, Giulio, Pinna, Valentina, Pivnick, Eniko K, Pond, Dinel A, Powell, Cynthia M, Rogers, Caleb, Shahar, Noa Ruhrman, Rutledge, S. Lane, Saletti, Veronica, Sandaradura, Sarah A, Santoro, Claudia, Schatz, Ulrich A, Schreiber, Allison, Scott, Daryl A, Sellars, Elizabeth A, Sheffer, Ruth, Siqveland, Elizabeth, Slopis, John M, Smith, Rosemarie, Spalice, Alberto, Stockton, David W, Streff, Haley, Theos, Amy, Tomlinson, Gail E, Tran, Grace, Trapane, Pamela L, Trevisson, Eva, Ullrich, Nicole J, Van den Ende, Jenneke, Vergano, Samantha A. Schrier, Wallace, Stephanie E, Wangler, Michael F, Weaver, David D, Yohay, Kaleb H, Zackai, Elaine, Zonana, Jonathan

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