Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase von Frezza, Christian, Zheng, Liang, Folger, Ori, Rajagopalan, Kartik N., MacKenzie, Elaine D., Jerby, Livnat, Micaroni, Massimo, Chaneton, Barbara, Adam, Julie, Hedley, Ann, Kalna, Gabriela, Tomlinson, Ian P. M., Pollard, Patrick J., Watson, Dave G., Deberardinis, Ralph J., Shlomi, Tomer, Ruppin, Eytan, Gottlieb, Eyal

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The effects of mutational processes and selection on driver mutations across cancer types von Temko, Daniel, Tomlinson, Ian P. M., Severini, Simone, Schuster-Böckler, Benjamin, Graham, Trevor A.

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Mitochondrial tumour suppressors: a genetic and biochemical update von Gottlieb, Eyal, Tomlinson, Ian P. M

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Chromosomal Instability Confers Intrinsic Multidrug Resistance von LEE, Alvin J. X, ENDESFELDER, David, KSCHISCHO, Maik, SWANTON, Charles, ROWAN, Andrew J, WALTHER, Axel, BIRKBAK, Nicolai J, ANDREW FUTREAL, P, DOWNWARD, Julian, SZALLASI, Zoltan, TOMLINSON, Ian P. M, HOWELL, Michael

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Prognostic significance of POLE proofreading mutations in endometrial cancer von Church, David N, Stelloo, Ellen, Nout, Remi A, Valtcheva, Nadejda, Depreeuw, Jeroen, ter Haar, Natalja, Noske, Aurelia, Amant, Frederic, Tomlinson, Ian P M, Wild, Peter J, Lambrechts, Diether, Jürgenliemk-Schulz, Ina M, Jobsen, Jan J, Smit, Vincent T H B M, Creutzberg, Carien L, Bosse, Tjalling

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Replication stress links structural and numerical cancer chromosomal instability von Burrell, Rebecca A., McClelland, Sarah E., Endesfelder, David, Groth, Petra, Weller, Marie-Christine, Shaikh, Nadeem, Domingo, Enric, Kanu, Nnennaya, Dewhurst, Sally M., Gronroos, Eva, Chew, Su Kit, Rowan, Andrew J., Schenk, Arne, Sheffer, Michal, Howell, Michael, Kschischo, Maik, Behrens, Axel, Helleday, Thomas, Bartek, Jiri, Tomlinson, Ian P., Swanton, Charles

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Evaluation of PIK3CA Mutation As a Predictor of Benefit From Nonsteroidal Anti-Inflammatory Drug Therapy in Colorectal Cancer von DOMINGO, Enric, CHURCH, David N, SIEBER, Oliver, RAMAMOORTHY, Rajarajan, YANAGISAWA, Yoko, JOHNSTONE, Elaine, DAVIDSON, Brian, KERR, David J, TOMLINSON, Ian P. M, MIDGLEY, Rachel

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Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer von MOURADOV, Dmitri, SLOGGETT, Clare, O'CONNOR, Liam, WILDING, Jennifer L, BICKNELL, David, TOMLINSON, Ian P. M, BODMER, Walter F, MARIADASON, John M, SIEBER, Oliver M, JORISSEN, Robert N, LOVE, Christopher G, SHAN LI, BURGESS, Antony W, ARANGO, Diego, STRAUSBERG, Robert L, BUCHANAN, Daniel, WORMALD, Samuel

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Measuring single cell divisions in human tissues from multi-region sequencing data von Werner, Benjamin, Case, Jack, Williams, Marc J., Chkhaidze, Ketevan, Temko, Daniel, Fernández-Mateos, Javier, Cresswell, George D., Nichol, Daniel, Cross, William, Spiteri, Inmaculada, Huang, Weini, Tomlinson, Ian P. M., Barnes, Chris P., Graham, Trevor A., Sottoriva, Andrea

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The importance of p53 pathway genetics in inherited and somatic cancer genomes von Stracquadanio, Giovanni, Wang, Xuting, Wallace, Marsha D., Grawenda, Anna M., Zhang, Ping, Hewitt, Juliet, Zeron-Medina, Jorge, Castro-Giner, Francesc, Tomlinson, Ian P., Goding, Colin R., Cygan, Kamil J., Fairbrother, William G., Thomas, Laurent F., Sætrom, Pål, Gemignani, Federica, Landi, Stefano, Schuster-Böckler, Benjamin, Bell, Douglas A., Bond, Gareth L.

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Cell longevity and sustained primary growth in palm stems von Tomlinson, P. Barry, Huggett, Brett A

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Holoparasitic Rafflesiaceae possess the most reduced endophytes and yet give rise to the world's largest flowers von Nikolov, Lachezar A, Tomlinson, P. B, Manickam, Sugumaran, Endress, Peter K, Kramer, Elena M, Davis, Charles C

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Phylogenetic and functional signals in gymnosperm ovular secretions von Nepi, Massimo, Little, Stefan, Guarnieri, Massimo, Nocentini, Daniele, Prior, Natalie, Gill, Julia, Tomlinson, P. Barry, Ickert-Bond, Stefanie M., Pirone, Cary, Pacini, Ettore, von Aderkas, Patrick

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Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study von Zhang, Xiaomeng, Theodoratou, Evropi, Li, Xue, Farrington, Susan M., Law, Philip J., Broderick, Peter, Walker, Marion, Klimentidis, Yann C., Rees, Jessica M. B., Houlston, Richard S., Tomlinson, Ian P. M., Burgess, Stephen, Campbell, Harry, Dunlop, Malcolm G., Timofeeva, Maria

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Genomic Evolution and Transcriptional Changes in the Evolution of Prostate Cancer into Neuroendocrine and Ductal Carcinoma Types von Rao, Srinivasa R, Protheroe, Andrew, Cerundolo, Lucia, Maldonado-Perez, David, Browning, Lisa, Lamb, Alastair D, Bryant, Richard J, Mills, Ian G, Woodcock, Dan J, Hamdy, Freddie C, Tomlinson, Ian P M, Verrill, Clare

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Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank von Zhang, Xiaomeng, Li, Xue, He, Yazhou, Law, Philip J., Farrington, Susan M., Campbell, Harry, Tomlinson, Ian P. M., Houlston, Richard S., Dunlop, Malcolm G., Timofeeva, Maria, Theodoratou, Evropi

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PHLDA1 Expression Marks the Putative Epithelial Stem Cells and Contributes to Intestinal Tumorigenesis von SAKTHIANANDESWAREN, Anuratha, CHRISTIE, Michael, RAMSAY, Robert G, PHESSE, Toby J, ERNST, Matthias, JEFFERY, Rosemary E, POULSOM, Richard, LEEDHAM, Simon J, SEGDITSAS, Stefania, TOMLINSON, Ian P. M, BERNHARD, Oliver K, SIMPSON, Richard J, D'ANDRETI, Carla, WALKER, Francesca, FAUX, Maree C, CHURCH, Nicole, CATIMEL, Bruno, FLANAGAN, Dustin J, VINCAN, Elizabeth, SIEBER, Oliver M, TSUI, Cary, JORISSEN, Robert N, SHAN LI, FLEMING, Nicholas I, GIBBS, Peter, LIPTON, Lara, MALATERRE, Jordane

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Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression von Schödel, Johannes, Bardella, Chiara, Sciesielski, Lina K, Brown, Jill M, Pugh, Chris W, Buckle, Veronica, Tomlinson, Ian P, Ratcliffe, Peter J, Mole, David R

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KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer von TIE, Jeanne, LIPTON, Lara, PICK, Adrian W, KNIGHT, Simon, CARNE, Peter W. G, BERRY, Roger, POLGLASE, Adrian, MCMURRICK, Paul, QI ZHAO, BUSAM, Dana, STRAUSBERG, Robert L, DOMINGO, Enric, DESAI, Jayesh, TOMLINSON, Ian P. M, MIDGLEY, Rachel, KERR, David, SIEBER, Oliver M, GIBBS, Peter, JORISSEN, Robert N, CHRISTIE, Michael, DRUMMOND, Katharine J, THOMSON, Benjamin N. J, USATOFF, Valery, EVANS, Peter M

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The FH mutation database: an online database of fumarate hydratase mutations involved in the MCUL (HLRCC) tumor syndrome and congenital fumarase deficiency von Bayley, Jean-Pierre, Launonen, Virpi, Tomlinson, Ian P M

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