Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk von Webb, E, Broderick, P, Chandler, I, Lubbe, S, Penegar, S, Tomlinson, I P M, Houlston, R S

Volltext

Common genetic variation contributes significantly to the risk of childhood B-cell precursor acute lymphoblastic leukemia von Enciso-Mora, V, Hosking, F J, Sheridan, E, Kinsey, S E, Lightfoot, T, Roman, E, Irving, J A E, Tomlinson, I P M, Allan, J M, Taylor, M, Greaves, M, Houlston, R S

Volltext

comprehensive genetic profile of phyllodes tumours of the breast detects important mutations, intra-tumoral genetic heterogeneity and new genetic changes on recurrence von Jones, AM, Mitter, R, Springall, R, Graham, T, Winter, E, Gillett, C, Hanby, AM, Tomlinson, IPM, Sawyer, EJ

Volltext

Anti-serum albumin domain antibodies for extending the half-lives of short lived drugs von Holt, Lucy J., Basran, Amrik, Jones, Kate, Chorlton, Jennifer, Jespers, Laurent S., Brewis, Neil D., Tomlinson, Ian M.

Volltext

Isolation of high affinity human antibodies directly from large synthetic repertoires von Griffiths, A.D., Williams, S.C., Hartley, O., Tomlinson, I.M., Waterhouse, P., Crosby, W.L., Kontermann, R.E., Jones, P.T., Low, N.M., Allison, T.J.

Volltext

The structural repertoire of the human V kappa domain von Tomlinson, I. M., Cox, J. P., Gherardi, E., Lesk, A. M., Chothia, C.

Volltext

β -Catenin Mutations in Cell Lines Established from Human Colorectal Cancers von Ilyas, M., Tomlinson, I. P. M., Rowan, A., Pignatelli, M., Bodmer, W. F.

Volltext

APC and the three-hit hypothesis von Segditsas, S, Rowan, A J, Howarth, K, Jones, A, Leedham, S, Wright, N A, Gorman, P, Chambers, W, Domingo, E, Roylance, R R, Sawyer, E J, Sieber, O M, Tomlinson, I P M

Volltext

Location in the large bowel influences the APC mutations observed in FAP adenomas von Will, O. C., Leedham, S. J., Elia, G., Phillips, R. K. S., Clark, S. K., Tomlinson, I. P. M.

Volltext

Molecular classification and genetic pathways in hyperplastic polyposis syndrome von Carvajal-Carmona, LG, Howarth, KM, Lockett, M, Polanco-Echeverry, GM, Volikos, E, Gorman, M, Barclay, E, Martin, L, Jones, AM, Saunders, B, Guenther, T, Donaldson, A, Paterson, J, Frayling, I, Novelli, MR, Phillips, R, Thomas, HJW, Silver, A, Atkin, W, Tomlinson, IPM

Volltext

mRNA expression profiling of phyllodes tumours of the breast: identification of genes important in the development of borderline and malignant phyllodes tumours von Jones, AM, Mitter, R, Poulsom, R, Gillett, C, Hanby, AM, Consortium, Phyllodes Tumour, Tomlinson, IPM, Sawyer, EJ

Volltext

Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation von Sieber, O M, Segditsas, S, Knudsen, A L, Zhang, J, Luz, J, Rowan, A J, Spain, S L, Thirlwell, C, Howarth, K M, Jaeger, E E M, Robinson, J, Volikos, E, Silver, A, Kelly, G, Aretz, S, Frayling, I, Hutter, P, Dunlop, M, Guenther, T, Neale, K, Phillips, R, Heinimann, K, Tomlinson, I P M

Volltext

Sequence and Evolution of the Human Germline V λRepertoire von Williams, Samuel C., Frippiat, Jean-Pol, Tomlinson, Ian M., Ignatovich, Olga, Lefranc, Marie-Paule, Winter, Greg

Volltext

Domain antibodies: proteins for therapy von Holt, Lucy J, Herring, Chris, Jespers, Laurent S, Woolven, Benjamin P, Tomlinson, Ian M

Volltext

Antibody arrays for high-throughput screening of antibody-antigen interactions von de Wildt, Ruud M. T, Tomlinson, Ian M, Mundy, Chris R, Gorick, Barbara D

Volltext

Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis von Christie, M, Jorissen, R N, Mouradov, D, Sakthianandeswaren, A, Li, S, Day, F, Tsui, C, Lipton, L, Desai, J, Jones, I T, McLaughlin, S, Ward, R L, Hawkins, N J, Ruszkiewicz, A R, Moore, J, Burgess, A W, Busam, D, Zhao, Q, Strausberg, R L, Simpson, A J, Tomlinson, I P M, Gibbs, P, Sieber, O M

Volltext

Molecular characteristics of serrated adenomas of the colorectum von Sawyer, E J, Cerar, A, Hanby, A M, Gorman, P, Arends, M, Talbot, I C, Tomlinson, I P M

Volltext

An Ancestral Ashkenazi Haplotype at the HMPS/CRAC1 Locus on 15q13–q14 Is Associated with Hereditary Mixed Polyposis Syndrome von Jaeger, E.E.M., Woodford-Richens, K.L., Lockett, M., Rowan, A.J., Sawyer, E.J., Heinimann, K., Rozen, P., Murday, V.A., Whitelaw, S.C., Ginsberg, A., Atkin, W.S., Lynch, H.T., Southey, M.C., Debinski, H., Eng, C., Bodmer, W.F., Talbot, I.C., Hodgson, S.V., Thomas, H.J.W., Tomlinson, I.P.M.

Volltext

Most low-level microsatellite instability in colorectal cancers can be explained without an elevated slippage rate von Graham, T, Halford, S, Page, KM, Tomlinson, IPM

Volltext