Cystathionine-β-Synthase: Molecular Regulation and Pharmacological Inhibition von Zuhra, Karim, Augsburger, Fiona, Majtan, Tomas, Szabo, Csaba

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Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndro... von Panagaki, Theodora, Lozano-Montes, Laura, Janickova, Lucia, Zuhra, Karim, Szabo, Marcell P., Majtan, Tomas, Rainer, Gregor, Maréchal, Damien, Herault, Yann, Szabo, Csaba

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Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase by S-adenosylmethionine von Ereño-Orbea, June, Majtan, Tomas, Oyenarte, Iker, Kraus, Jan P, Martínez-Cruz, Luis Alfonso

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Effect of honey and its major royal jelly protein 1 on cytokine and MMP-9 mRNA transcripts in human keratinocytes von Majtan, Juraj, Kumar, Pawan, Majtan, Tomas, Walls, Andrew F., Klaudiny, Jaroslav

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Catalytic specificity and crystal structure of cystathionine γ-lyase from Pseudomonas aeruginosa von Pedretti, Marco, Fernández-Rodríguez, Carmen, Conter, Carolina, Oyenarte, Iker, Favretto, Filippo, di Matteo, Adele, Dominici, Paola, Petrosino, Maria, Martinez-Chantar, Maria Luz, Majtan, Tomas, Astegno, Alessandra, Martínez-Cruz, Luis Alfonso

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Structural basis of regulation and oligomerization of human cystathionine β-synthase, the central enzyme of transsulfuration von Ereño-Orbea, June, Majtan, Tomas, Oyenarte, Iker, Kraus, Jan P, Martínez-Cruz, Luis Alfonso

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Enzyme replacement prevents neonatal death, liver damage, and osteoporosis in murine homocystinuria von Majtan, Tomas, Hůlková, Helena, Park, Insun, Krijt, Jakub, Kožich, Viktor, Bublil, Erez M., Kraus, Jan P.

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Mechanism of action and impact of thiol homeostasis on efficacy of an enzyme replacement therapy for classical homocystinuria von Philipp, Thilo Magnus, Bottiglieri, Teodoro, Clapper, Wilmelenne, Liu, Kai, Rodems, Steve, Szabo, Csaba, Majtan, Tomas

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Interplay of Enzyme Therapy and Dietary Management of Murine Homocystinuria von Park, Insun, Bublil, Erez M, Glavin, Frank, Majtan, Tomas

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Genetic and Pharmacological Modulation of Cellular Proteostasis Leads to Partial Functional Rescue of Homocystinuria-Causing Cystathionine-Beta Synthase Variants von Collard, Renata, Majtan, Tomas

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Deciphering pathophysiological mechanisms underlying cystathionine beta-synthase-deficient homocystinuria using targeted metabolomics, liver proteomics, sphingolipidomics and analy... von Majtan, Tomas, Olsen, Thomas, Sokolova, Jitka, Krijt, Jakub, Křížková, Michaela, Ida, Tomoaki, Ditrói, Tamás, Hansikova, Hana, Vit, Ondrej, Petrak, Jiri, Kuchař, Ladislav, Kruger, Warren D., Nagy, Péter, Akaike, Takaaki, Kožich, Viktor

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Komrower Memorial Lecture 2023. Molecular basis of phenotype expression in homocystinuria: Where are we 30years later? von Kožich, Viktor, Majtan, Tomas

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Domain organization, catalysis and regulation of eukaryotic cystathionine beta-synthases von Majtan, Tomas, Pey, Angel L, Fernández, Roberto, Fernández, José A, Martínez-Cruz, Luis A, Kraus, Jan P

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Thioethers as markers of hydrogen sulfide production in homocystinurias von Kožich, Viktor, Krijt, Jakub, Sokolová, Jitka, Melenovská, Petra, Ješina, Pavel, Vozdek, Roman, Majtán, Tomáš, Kraus, Jan P.

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Detection of the Class 1 Integrons and SGI1 among Salmonella enterica Serovar Typhimurium DT104, U302, DT120, DT193, and Nontypable Human Isolates von Majtánová, L'ubica, Majtán, Tomáš, Majtán, Viktor

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A key leader in homocystinuria research: Jan P. Kraus (1942–2019) von Kožich, Viktor, Majtan, Tomas

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Komrower Memorial Lecture 2023. Molecular basis of phenotype expression in homocystinuria: Where are we 30 years later? von Kožich, Viktor, Majtan, Tomas

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Emerging therapeutic approaches to cystathionine beta-synthase-deficient homocystinuria von Majtan, Tomas, Kožich, Viktor, Kruger, Warren D.

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Hypermethioninemia Leads to Fatal Bleeding and Increased Mortality in a Transgenic I278T Mouse Model of Homocystinuria von Park, Insun, Johnson, Linda K., Cox, Allaura, Branchford, Brian R., Paola, Jorge Di, Bublil, Erez M., Majtan, Tomas

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Cellular turnover and degradation of the most common missense cystathionine beta‐synthase variants causing homocystinuria von Mijatovic, Ela, Ascenção, Kelly, Szabo, Csaba, Majtan, Tomas

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