Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses von Saunders, Kevin O., Lee, Esther, Parks, Robert, Martinez, David R., Li, Dapeng, Chen, Haiyan, Edwards, Robert J., Gobeil, Sophie, Barr, Maggie, Mansouri, Katayoun, Alam, S. Munir, Sutherland, Laura L., Cai, Fangping, Sanzone, Aja M., Berry, Madison, Manne, Kartik, Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Kapingidza, Anyway B., Azoitei, Mihai, Tse, Longping V., Scobey, Trevor D., Spreng, Rachel L., Rountree, R. Wes, DeMarco, C. Todd, Denny, Thomas N., Woods, Christopher W., Petzold, Elizabeth W., Tang, Juanjie, Oguin, Thomas H., Sempowski, Gregory D., Gagne, Matthew, Douek, Daniel C., Tomai, Mark A., Fox, Christopher B., Seder, Robert, Wiehe, Kevin, Weissman, Drew, Pardi, Norbert, Golding, Hana, Khurana, Surender, Acharya, Priyamvada, Andersen, Hanne, Lewis, Mark G., Moore, Ian N., Montefiori, David C., Baric, Ralph S., Haynes, Barton F.

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Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies von Mullins, Stefanie R., Vasilakos, John P., Deschler, Katharina, Grigsby, Iwen, Gillis, Pete, John, Julius, Elder, Matthew J., Swales, John, Timosenko, Elina, Cooper, Zachary, Dovedi, Simon J., Leishman, Andrew J., Luheshi, Nadia, Elvecrog, James, Tilahun, Ashenafi, Goodwin, Richard, Herbst, Ronald, Tomai, Mark A., Wilkinson, Robert W.

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Synthetic TLR Agonists Reveal Functional Differences between Human TLR7 and TLR8 von Gorden, Keith B, Gorski, Kevin S, Gibson, Sheila J, Kedl, Ross M, Kieper, William C, Qiu, Xiaohong, Tomai, Mark A, Alkan, Sefik S, Vasilakos, John P

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A molecular atlas of innate immunity to adjuvanted and live attenuated vaccines, in mice von Lee, Audrey, Scott, Madeleine K. D., Wimmers, Florian, Arunachalam, Prabhu S., Luo, Wei, Fox, Christopher B., Tomai, Mark, Khatri, Purvesh, Pulendran, Bali

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Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1–dependent pathways von Philbin, Victoria J., DPhil, Dowling, David J., PhD, Gallington, Leighanne C., BSc, Cortés, Guadalupe, PhD, Tan, Zhen, MD, Suter, Eugénie E., MA, Chi, Kevin W., BA, Shuckett, Ariel, MPH, Stoler-Barak, Liat, MSc, Tomai, Mark, PhD, Miller, Richard L., PhD, Mansfield, Keith, DVM, Levy, Ofer, MD, PhD

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Optimizing immunogenicity and product presentation of a SARS-CoV-2 subunit vaccine composition: effects of delivery route, heterologous regimens with self-amplifying RNA vaccines,... von Lykins, William R, Pollet, Jeroen, White, Jessica A, Keegan, Brian, Versteeg, Leroy, Strych, Ulrich, Chen, Wen-Hsiang, Mohamath, Raodoh, Ramer-Denisoff, Gabi, Reed, Sierra, Renshaw, Christina, Beaver, Samuel, Gerhardt, Alana, Voigt, Emily A, Tomai, Mark A, Sitrin, Robert, Choy, Robert K M, Cassels, Frederick J, Hotez, Peter J, Bottazzi, Maria Elena, Fox, Christopher B

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Adsorption of a synthetic TLR7/8 ligand to aluminum oxyhydroxide for enhanced vaccine adjuvant activity: A formulation approach von Fox, Christopher B., Orr, Mark T., Van Hoeven, Neal, Parker, Sarah C., Mikasa, Traci J.T., Phan, Tony, Beebe, Elyse A., Nana, Ghislain I., Joshi, Sharvari W, Tomai, Mark A., Elvecrog, James, Fouts, Timothy R., Reed, Steven G.

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Optimizing a Multi-Component Intranasal Entamoeba Histolytica Vaccine Formulation Using a Design of Experiments Strategy von Abhyankar, Mayuresh M, Orr, Mark T, Kinsey, Robert, Sivananthan, Sandra, Nafziger, Andrew J, Oakland, David N, Young, Mary K, Farr, Laura, Uddin, Md Jashim, Leslie, Jhansi L, Burgess, Stacey L, Liang, Hong, De Lima, Ines, Larson, Elise, Guderian, Jeffrey A, Lin, Susan, Kahn, Aaron, Ghosh, Prakash, Reed, Sierra, Tomai, Mark A, Pedersen, Karl, Petri, Jr, William A, Fox, Christopher B

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Different adjuvanted pediatric HIV envelope vaccines induced distinct plasma antibody responses despite similar B cell receptor repertoires in infant rhesus macaques von Berendam, Stella J, Morgan-Asiedu, Papa K, Mangan, Riley J, Li, Shuk Hang, Heimsath, Holly, Luo, Kan, Curtis, 2nd, Alan D, Eudailey, Joshua A, Fox, Christopher B, Tomai, Mark A, Phillips, Bonnie, Itell, Hannah L, Kunz, Erika, Hudgens, Michael, Cronin, Kenneth, Wiehe, Kevin, Alam, S Munir, Van Rompay, Koen K A, De Paris, Kristina, Permar, Sallie R, Moody, M Anthony, Fouda, Genevieve G

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Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction von Wiehe, Kevin, Saunders, Kevin O., Stalls, Victoria, Cain, Derek W., Venkatayogi, Sravani, Martin Beem, Joshua S., Berry, Madison, Evangelous, Tyler, Henderson, Rory, Hora, Bhavna, Xia, Shi-Mao, Jiang, Chuancang, Newman, Amanda, Bowman, Cindy, Lu, Xiaozhi, Bryan, Mary E., Bal, Joena, Sanzone, Aja, Chen, Haiyan, Eaton, Amanda, Tomai, Mark A., Fox, Christopher B., Tam, Ying K., Barbosa, Christopher, Bonsignori, Mattia, Muramatsu, Hiromi, Alam, S. Munir, Montefiori, David C., Williams, Wilton B., Pardi, Norbert, Tian, Ming, Weissman, Drew, Alt, Frederick W., Acharya, Priyamvada, Haynes, Barton F.

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Immunogenicity and safety of an Entamoeba histolytica adjuvanted protein vaccine candidate (LecA+GLA-3M-052 liposomes) in rhesus macaques von Abhyankar, Mayuresh M., Xu, Feifan, Chavez, Deborah, Goodroe, Anna, Mendoza, Elda, Chen, Christopher, Singh, Dhiraj K., Varnador, Fernando, Sivananthan, Sandra J., Kinsey, Robert, Lykins, William R., Murphy, Brynn M., Martin, Andrew R., Tomai, Mark A., Ghosal, Soutik, Casper, Corey, Pedersen, Karl, Petri, William A., Fox, Christopher B.

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A Formulated TLR7/8 Agonist is a Flexible, Highly Potent and Effective Adjuvant for Pandemic Influenza Vaccines von Van Hoeven, Neal, Fox, Christopher B., Granger, Brian, Evers, Tara, Joshi, Sharvari W., Nana, Ghislain I., Evans, Sarah C., Lin, Susan, Liang, Hong, Liang, Li, Nakajima, Rie, Felgner, Philip L., Bowen, Richard A., Marlenee, Nicole, Hartwig, Airn, Baldwin, Susan L., Coler, Rhea N., Tomai, Mark, Elvecrog, James, Reed, Steven G., Carter, Darrick

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Nanoformulation of synergistic TLR ligands to enhance vaccination against Entamoeba histolytica von Abhyankar, Mayuresh M, Noor, Zannatun, Tomai, Mark A, Elvecrog, James, Fox, Christopher B, Petri, William A

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Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists von Gorski, Kevin S., Waller, Emily L., Bjornton-Severson, Jacqueline, Hanten, John A., Riter, Christie L., Kieper, William C., Gorden, Keith B., Miller, Jeffrey S., Vasilakos, John P., Tomai, Mark A., Alkan, Sefik S.

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TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth von Dowling, David J, van Haren, Simon D, Scheid, Annette, Bergelson, Ilana, Kim, Dhohyung, Mancuso, Christy J, Foppen, Willemina, Ozonoff, Al, Fresh, Lynn, Theriot, Terese B, Lackner, Andrew A, Fichorova, Raina N, Smirnov, Dmitri, Vasilakos, John P, Beaurline, Joe M, Tomai, Mark A, Midkiff, Cecily C, Alvarez, Xavier, Blanchard, James L, Gilbert, Margaret H, Aye, Pyone Pyone, Levy, Ofer

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Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine von Li, Dapeng, Martinez, David R., Schäfer, Alexandra, Chen, Haiyan, Barr, Maggie, Sutherland, Laura L., Lee, Esther, Parks, Robert, Mielke, Dieter, Edwards, Whitney, Newman, Amanda, Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Gagne, Matthew, Douek, Daniel C., DeMarco, C. Todd, Denny, Thomas N., Oguin, Thomas H., Brown, Alecia, Rountree, Wes, Wang, Yunfei, Mansouri, Katayoun, Edwards, Robert J., Ferrari, Guido, Sempowski, Gregory D., Eaton, Amanda, Tang, Juanjie, Cain, Derek W., Santra, Sampa, Pardi, Norbert, Weissman, Drew, Tomai, Mark A., Fox, Christopher B., Moore, Ian N., Andersen, Hanne, Lewis, Mark G., Golding, Hana, Seder, Robert, Khurana, Surender, Baric, Ralph S., Montefiori, David C., Saunders, Kevin O., Haynes, Barton F.

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Development of COVID-19 vaccine using a dual Toll-like receptor ligand liposome adjuvant von Abhyankar, Mayuresh M., Mann, Barbara J., Sturek, Jeffrey M., Brovero, Savannah, Moreau, G. Brett, Sengar, Anjali, Richardson, Crystal M., Agah, Sayeh, Pomés, Anna, Kasson, Peter M., Tomai, Mark A., Fox, Christopher B., Petri, William A.

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Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors von Schölch, Sebastian, Rauber, Conrad, Tietz, Alexandra, Rahbari, Nuh N, Bork, Ulrich, Schmidt, Thomas, Kahlert, Christoph, Haberkorn, Uwe, Tomai, Mark A, Lipson, Kenneth E, Carretero, Rafael, Weitz, Jürgen, Koch, Moritz, Huber, Peter E

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Early Post-Vaccination Gene Signatures Correlate With the Magnitude and Function of Vaccine-Induced HIV Envelope-Specific Plasma Antibodies in Infant Rhesus Macaques von Vijayan, K K Vidya, Cross, Kaitlyn A, Curtis, 2nd, Alan D, Van Rompay, Koen K A, Pollara, Justin, Fox, Christopher B, Tomai, Mark, Hanke, Tomáš, Fouda, Genevieve, Hudgens, Michael G, Permar, Sallie R, De Paris, Kristina

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Adjuvant composition and delivery route shape immune response quality and protective efficacy of a recombinant vaccine for Entamoeba histolytica von Abhyankar, Mayuresh M., Orr, Mark T., Lin, Susan, Suraju, Mohammed O., Simpson, Adrian, Blust, Molly, Pham, Tiep, Guderian, Jeffrey A., Tomai, Mark A., Elvecrog, James, Pedersen, Karl, Petri, William A., Fox, Christopher B.

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