Discovery of potent allosteric antibodies inhibiting EGFR von Fournier, Léxane, Pekar, Lukas, Leuthner, Birgitta, Kolmar, Harald, Toleikis, Lars, Becker, Stefan

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Bi-specific Aptamers Mediating Tumor Cell Lysis von Boltz, Achim, Piater, Birgit, Toleikis, Lars, Guenther, Ralf, Kolmar, Harald, Hock, Bjoern

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Generation and analysis of the improved human HAL9/10 antibody phage display libraries von Kügler, Jonas, Wilke, Sonja, Meier, Doris, Tomszak, Florian, Frenzel, André, Schirrmann, Thomas, Dübel, Stefan, Garritsen, Henk, Hock, Björn, Toleikis, Lars, Schütte, Mark, Hust, Michael

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Biophysical and biochemical characterization of a VHH-based IgG-like bi- and trispecific antibody platform von Pekar, Lukas, Busch, Michael, Valldorf, Bernhard, Hinz, Steffen C, Toleikis, Lars, Krah, Simon, Zielonka, Stefan

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Beyond bispecificity: Controlled Fab arm exchange for the generation of antibodies with multiple specificities von Yanakieva, Desislava, Pekar, Lukas, Evers, Andreas, Fleischer, Markus, Keller, Stephan, Mueller-Pompalla, Dirk, Toleikis, Lars, Kolmar, Harald, Zielonka, Stefan, Krah, Simon

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Intein mediated high throughput screening for bispecific antibodies von Hofmann, Tim, Schmidt, Johannes, Ciesielski, Elke, Becker, Stefan, Rysiok, Thomas, Schütte, Mark, Toleikis, Lars, Kolmar, Harald, Doerner, Achim

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Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent... von Pekar, Lukas, Klewinghaus, Daniel, Arras, Paul, Carrara, Stefania C, Harwardt, Julia, Krah, Simon, Yanakieva, Desislava, Toleikis, Lars, Smider, Vaughn V, Kolmar, Harald, Zielonka, Stefan

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A One-Step Process for the Construction of Phage Display scFv and VHH Libraries von Sellmann, Carolin, Pekar, Lukas, Bauer, Christina, Ciesielski, Elke, Krah, Simon, Becker, Stefan, Toleikis, Lars, Kügler, Jonas, Frenzel, André, Valldorf, Bernhard, Hust, Michael, Zielonka, Stefan

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Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers von Boje, Ammelie Svea, Pekar, Lukas, Koep, Katharina, Lipinski, Britta, Rabinovich, Brian, Evers, Andreas, Gehlert, Carina Lynn, Krohn, Steffen, Xiao, Yanping, Krah, Simon, Zaynagetdinov, Rinat, Toleikis, Lars, Poetzsch, Sven, Peipp, Matthias, Zielonka, Stefan, Klausz, Katja

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Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition von Lipinski, Britta, Unmuth, Laura, Arras, Paul, Becker, Stefan, Bauer, Christina, Toleikis, Lars, Krah, Simon, Doerner, Achim, Yanakieva, Desislava, Boje, Ammelie Svea, Klausz, Katja, Peipp, Matthias, Siegmund, Vanessa, Evers, Andreas, Kolmar, Harald, Pekar, Lukas, Zielonka, Stefan

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Avelumab internalization by human circulating immune cells is mediated by both Fc gamma receptor and PD-L1 binding von Jin, Hulin, D'Urso, Vittorio, Neuteboom, Berend, McKenna, Sean D., Schweickhardt, Rene, Gross, Alec W., Fomekong Nanfack, Yves, Paoletti, Andrea, Carter, Carina, Toleikis, Lars, Fluck, Markus, Scheuenpflug, Juergen, Cai, Ti

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A novel one-step approach for the construction of yeast surface display Fab antibody libraries von Rosowski, Simon, Becker, Stefan, Toleikis, Lars, Valldorf, Bernhard, Grzeschik, Julius, Demir, Deniz, Willenbücher, Iris, Gaa, Ramona, Kolmar, Harald, Zielonka, Stefan, Krah, Simon

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A generic approach to engineer antibody pH-switches using combinatorial histidine scanning libraries and yeast display von Schröter, Christian, Günther, Ralf, Rhiel, Laura, Becker, Stefan, Toleikis, Lars, Doerner, Achim, Becker, Janine, Schönemann, Andreas, Nasu, Daichi, Neuteboom, Berend, Kolmar, Harald, Hock, Björn

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Rise and fall of an anti-MUC1 specific antibody von Thie, Holger, Toleikis, Lars, Li, Jiandong, von Wasielewski, Reinhard, Bastert, Gunther, Schirrmann, Thomas, Esteves, Isabel Tourais, Behrens, Christian K, Fournes, Bénédict, Fournier, Nathalie, de Romeuf, Christophe, Hust, Michael, Dübel, Stefan

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Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug Conjugates von Sellmann, Carolin, Doerner, Achim, Knuehl, Christine, Rasche, Nicolas, Sood, Vanita, Krah, Simon, Rhiel, Laura, Messemer, Annika, Wesolowski, John, Schuette, Mark, Becker, Stefan, Toleikis, Lars, Kolmar, Harald, Hock, Bjoern

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A platform for the early selection of non-competitive antibody-fragments from yeast surface display libraries von Fournier, Léxane, Demir, Deniz, Elter, Desislava, Pekar, Lukas, Kolmar, Harald, Toleikis, Lars, Becker, Stefan

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Facile One-Step Generation of Camelid VHH and Avian scFv Libraries for Phage Display by Golden Gate Cloning von Bauer, Christina, Ciesielski, Elke, Pekar, Lukas, Krah, Simon, Toleikis, Lars, Zielonka, Stefan, Sellmann, Carolin

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Multifunctional NK Cell–Engaging Antibodies Targeting EGFR and NKp30 Elicit Efficient Tumor Cell Killing and Proinflammatory Cytokine Release von Klausz, Katja, Pekar, Lukas, Boje, Ammelie Svea, Gehlert, Carina Lynn, Krohn, Steffen, Gupta, Tushar, Xiao, Yanping, Krah, Simon, Zaynagetdinov, Rinat, Lipinski, Britta, Toleikis, Lars, Poetzsch, Sven, Rabinovich, Brian, Peipp, Matthias, Zielonka, Stefan

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Affinity Maturation of B7-H6 Translates into Enhanced NK Cell-Mediated Tumor Cell Lysis and Improved Proinflammatory Cytokine Release of Bispecific Immunoligands via NKp30 Engageme... von Pekar, Lukas, Klausz, Katja, Busch, Michael, Valldorf, Bernhard, Kolmar, Harald, Wesch, Daniela, Oberg, Hans-Heinrich, Krohn, Steffen, Boje, Ammelie Svea, Gehlert, Carina Lynn, Toleikis, Lars, Krah, Simon, Gupta, Tushar, Rabinovich, Brian, Zielonka, Stefan, Peipp, Matthias

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Isolation of Antigen-Specific VHH Single-Domain Antibodies by Combining Animal Immunization with Yeast Surface Display von Roth, Lukas, Krah, Simon, Klemm, Janina, Günther, Ralf, Toleikis, Lars, Busch, Michael, Becker, Stefan, Zielonka, Stefan

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