Etrolizumab for the Treatment of Ulcerative Colitis and Crohn’s Disease: An Overview of the Phase 3 Clinical Program von Sandborn, William J., Vermeire, Severine, Tyrrell, Helen, Hassanali, Azra, Lacey, Stuart, Tole, Swati, Tatro, Amanda R.

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Effectiveness and cost-effectiveness of strategies to expand antiretroviral therapy in St. Petersburg, Russia von LONG, Elisa F, BRANDEAU, Margaret L, GALVIN, Cristina M, VINICHENKO, Tatyana, TOLE, Swati P, SCHWARTZ, Adam, SANDERS, Gillian D, OWENS, Douglas K

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The role of integrins in the pathogenesis of inflammatory bowel disease: Approved and investigational anti‐integrin therapies von Dotan, Iris, Allez, Matthieu, Danese, Silvio, Keir, Mary, Tole, Swati, McBride, Jacqueline

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P003 INFLAMMATORY BOWEL DISEASE PATIENTS’ PERSPECTIVES OF CLINICAL TRIALS von Rubin, David, Peyrin-Biroulet, Laurent, Reinisch, Walter, Tole, Swati, Sullivan, Laura, Park, K T, Regueiro, Miguel

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Sa1786 INFLAMMATORY BOWEL DISEASE PATIENTS' PERSPECTIVES OF CLINICAL TRIALS von Rubin, David T., Peyrin-Biroulet, Laurent, Reinisch, Walter, Tole, Swati, Sullivan, Laura, Park, Kun Tae, Regueiro, Miguel D.

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P003 INFLAMMATORY BOWEL DISEASE PATIENTS’ PERSPECTIVES OF CLINICAL TRIALS von Rubin, David, Peyrin-Biroulet, Laurent, Reinisch, Walter, Tole, Swati, Sullivan, Laura, Park, KT, Regueiro, Miguel

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Defining Endpoints and Biomarkers in Inflammatory Bowel Disease: Moving the Needle Through Clinical Trial Design von Abreu, Maria T., Sandborn, William J., Cataldi, Fabio, D'Haens, Geert, Feagan, Brian G., Hanauer, Stephen, Jairath, Vipul, Lakatos, Peter, Leptak, Christopher, McGovern, Dermot, Mulberg, Andrew, Panes, Julian, Parikh, Asit, Peyrin-Biroulet, Laurent, Reinisch, Walter, Riddell, Robert, Rubin, David, Sands, Bruce, Spleiss, Johannes, Strauss, Richard, Tole, Swati, Tomaino, Juli

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An Open-Label Tolerability and Actual-Use Human Factors Study of Etrolizumab Autoinjector in Healthy Volunteers von Tyrrell, Helen, Ravanello, Renato, Pulley, Jennifer, Tang, Meina Tao, Zhang, Wenhui, Abouhossein, Mariam, Tole, Swati

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Etrolizumab for the Treatment of Ulcerative Colitis and Crohn's Disease: An Overview of the Phase 3 Clinical Program von Sandborn, William J, Vermeire, Severine, Tyrrell, Helen, Hassanali, Azra, Lacey, Stuart, Tole, Swati, Tatro, Amanda R

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Etrolizumab as induction and maintenance therapy for ulcerative colitis in patients previously treated with tumour necrosis factor inhibitors (HICKORY): a phase 3, randomised, cont... von Hart, Ailsa, Oh, Young S, Tole, Swati, Lacey, Stuart, Aguilar, Humberto, Altorjay, Istvan, Andreu Garcia, Montserrat, Armuzzi, Alessandro, Avni-Biron, Irit, Ayub, Kamran, Baert, Filip, Bassan, Isaac, Behm, Brian, Bennett, Michael, Bernstein, Charles, Bettenworth, Dominik, Bloom, Stuart, Bosques Padilla, Francisco Javier, Bressler, Brian, Brückner, Markus, Chapman, Jonathon, Cheon, Jae Hee, Corlin, Richard, Dalal, Robin, Danese, Silvio, Desreumaux, Pierre, Di Felice Boratto, Sandra, Ding, John Nik, Du Vall, George Aaron, Ferreira de Almeida Borges, Valéria, Fleisher, Mark, Fries, Walter, Fumery, Mathurin, Gilletta de Saint Joseph, Cyrielle, Ginsburg, Philip, Goldin, Eran, Gomez Jaramillo, Hector Alejandro, Grimaud, Jean-Charles, Gutierrez, Alexandra, Hahm, Ki Baik, Hanauer, Stephen, Hanson, John, Harlan III, William, Hayee, Buhussain, Higgins, Peter, Hoentjen, Frank, Howaldt, Stefanie, Jagarlamudi, Kiran, Jansen, Jeroen, Katz, Lior, Katz, Seymour, Khanna, Reena, Kim, Joo Sung, Kleczkowski, Dariusz, Kronborg, Ian, Lee, Kang-Moon, Levine, Henry, Lukas, Milan, Martin Arranz, Maria Dolores, Meder, Agnieszka, Mertens, Jessica, Moore, Gregory, Neurath, Markus, Nguyen, Augustin, Panaccione, Remo, Park, Jihye, Peck-Radosavljevic, Markus, Peerani, Farhad, Pesta, Martin, Peyrin-Biroulet, Laurent, Prochazka, Vlastimil, Racz, Istvan, Radford-Smith, Graham, Ramos Castañeda, Daniel, Ramos Júnior, Odery, Rogai, Francesca, Rubin, David, Salamon, Agnes, Samuel, Douglas, Savarino, Edoardo Vincenzo, Schreiber, Stefan, Scott, John, Sedghi, Shahriar, Seidelin, Jakob, Shafran, Ira, Staessen, Dirk, Sultan, Keith, Tanno, Hugo, Thin, Lena, Vermeire, Severine, Villa, Erica, Volfova, Miroslava, Vuitton, Lucine, Wahab, Peter, Waterman, Mattitiahu, Weber, John, Weiss, L. Michael, Wozniak-Stolarska, Barbara, Younes, Ziad, Zeuzem, Stefan

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Etrolizumab versus infliximab for the treatment of moderately to severely active ulcerative colitis (GARDENIA): a randomised, double-blind, double-dummy, phase 3 study von Gisbert, Javier P, Hayee, Bu'hussain, Oh, Young S, Tole, Swati, Chai, Akiko, Aboo, Nazimuddin, Ahmad, Tariq, Allez, Matthieu, Altwegg, Romain, Ardizzone, Sandro, Armuzzi, Alessandro, Aumais, Guy, Avni-Biron, Irit, Bezuidenhout, Abraham, Blaeker, Michael, Bossa, Fabrizio, Bossuyt, Peter, Bouguen, Guillaume, Bourdages, Raymond, Brand, Stephan, Calvet Calvo, Xavier, Carbonnel, Franck, Cotter, Jose, De Maeyer, Marc, Desai, Milind, Desreumaux, Pierre, Dewit, Olivier, Dumitrascu, Dan Lucian, Ebert, Matthias, Eun, Chang Soo, Feagan, Brian, Fidalgo, Catarina, Fishman, Sigal, Flourié, Bernard, Fumery, Mathurin, G Kiss, Gyula, Gassner, Sonja, Gaya, Daniel, Gheorghe, Liliana Simona, Goldis, Adrian-Eugen, Gonçalves, Raquel, Hagege, Herve, Hindryckx, Pieter, Hrdlicka, Ludek, Huh, Kyu Chan, Iborra Colomino, Maria Isabel, Jansen, Jeroen, Jeon, Seong Woo, Kejariwal, Deepak, Khanna, Reena, Kim, Duk Hwan, Kim, Joo Sung, Kim, Kueongok, Kim, Kyung-Jo, Kim, Young-Ho, Kojecky, Vladimir, Koo, Ja Seol, Kozak, Robert, Kristof, Tunde, Kruger, Frederik, Lahat-zok, Adi, Lee, Jonghun, Lee, Kook Lae, Lee, YooJin, Limdi, Jimmy, Lopez Serrano, Pilar, Mana, Fazia, Mann, Steven, Mansfield, John, Marchi, Santino, Marino, Marco, Mateescu, Radu-Bogdan, Melzer, Ehud, Muls, Vinciane, Munuswamy, Pushpakaran, Naidoo, Visvakuren, Negreanu, Lucian, Nguyen, Augustin, Perez Gisbert, Javier, Peyrin-Biroulet, Laurent, Portela, Francisco, Racz, Istvan, Reimund, Jean-Marie, Roblin, Xavier, Rocca, Rodolfo, Salamon, Agnes, Salazar, Ennaliza, Samuel, Sunil, Selinger, Christian, Shim, Hang Hock, Siegmund, Britta, Simmonds, Wayne, Song, Geun Am, Sporea, Ioan, Stancu, George, Stoica, Victor, Taxonera Samso, Carlos, Thomson, John, Tichy, Michal, Vitek, Petr

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Tu2006 - Etrolizumab Induction Therapy Improves Histologic Outcomes in Anti-TNF-Failed Patients with Ulcerative Colitis: Results from the Hickory Open-Label Induction Cohort von Rubin, David T., Feagan, Brian G., Peyrin-Biroulet, Laurent, Pai, Rish K., Oh, Young S., Arulmani, Udayasankar, Boruvka, Audrey, Scherl, Alexis, Tyrrell, Helen, Tole, Swati

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Etrolizumab for maintenance therapy in patients with moderately to severely active ulcerative colitis (LAUREL): a randomised, placebo-controlled, double-blind, phase 3 study von Lakatos, Peter L, Ritter, Timothy, Hanauer, Stephen, Bressler, Brian, Khanna, Reena, Isaacs, Kim, Kadva, Alysha, Oh, Young S, Tole, Swati, Chai, Akiko, Eden, Christopher, Feagan, Brian G, Acir Crippa Júnior, Mauro, Ahmed, Tasneem, Altorjay, Istvan, Ausk, Karlee, Ayub, Kamran, Barbalaco Neto, Guerino, Bod, Barnabas, Brandão Mello, Carlos Eduardo, Brandeburova, Julia, Bressler, Brian, Chopey, Ivan, Connor, Michael, De, Arijit, Di Felice Boratto, Sandra, Dresner, David, Ehehalt, Robert, Ertan, Atilla, Etzel, Jason, Fallingborg, Jan, Feagan, Brian, Ferreira de Almeida Borges, Valéria, Fleisher, Mark, Fogel, Ronald, Franceschi Junior, Osvaldo, Gatof, David, Gokak, Vardaraj, Goldin, Eran, Gupta, Nitin, Hoffmann, Peter, Horvat, Gyula, Isaacs, Kim, Jensen, Søren, Johnson, Kenneth, Kalla, Mukesh, Karyotakis, Nicholas, Kaur, Nirmal, Larriva de los Reyes, Emmanuel, Leman, Bernard, Levine, Henry, Libanez Bessa Campelo Braga, Lúcia, Loftus, Edward, Lohdanidi, Tetiana, Longman, Randy, Madi-Szabo, Laszlo, Malluta, Everson Fernando, Martinez Silva, Francisca, Maynard, Kenneth, Mukewar, Shrikant, Neiko, Vasyl, Neurath, Markus, Novick, James, Pai, Nitin, Pandak, William, Pape, Ulrich-Frank, Parekh, Nimisha, Pesta, Martin, Peterfai, Eva, Piniella, Carlos, Prochazka, Vlastimil, Prokopchuk, Sergey, Prystupa, Ludmyla, Rainis, Tova, Ramos Júnior, Odery, Rishko, Iaroslava, Ritter, Timothy, Rozciecha, Jerzy, Rydzewska, Grazyna, Saibeni, Simone, Schnabel, Róbert, Segui, Armando, Seidelin, Jakob, Shah, Saumin, Sherman, Alex, Shukla, Akash, Sood, Ajit, Staun, Michael, Stein, Daniel, Steinberg, Alon, Steinhart, Hillary, Stifft, Jonathas, Tandon, Rakesh, Treiber, Matthias, Ulbrych, Jan, Velasco, Brenda, Witthoeft, Thomas, Yamamoto Furusho, Jesus Kazuo, Zborivskyy, Yaroslav, Zhdan, Vyacheslav

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20 ETROLIZUMAB IMPROVED ENDOSCOPIC SCORE, PATIENT-REPORTED OUTCOMES, AND INFLAMMATORY BIOMARKERS IN PATIENTS WITH MODERATE TO SEVERE UC WHO HAD FAILED TNF ANTAGONIST THERAPY: THE H... von Peyrin-Biroulet, Laurent, Rubin, David T., Feagan, Brian, Oh, Young S., Arulmani, Udayasankar, Tyrrell, Helen, Maciuca, Romeo, Williams, Sarah, Tole, Swati, Thommes, James

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Etrolizumab Treatment Leads to Early Improvement in Symptoms and Inflammatory Biomarkers in Anti-TNF-refractory Patients in the Open-Label Induction Cohort of the Phase 3 Hickory S... von Peyrin-Biroulet, Laurent, Feagan, Brian G., Mansfield, John, Rubin, David T., Arulmani, Udayasankar, Maciuca, Romeo, Tyrrell, Helen, Thommes, James, Tole, Swati

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Su1936 - Etrolizumab Treatment Leads to Early Improvement in Symptoms and Inflammatory Biomarkers in Anti-TNF-refractory Patients in the Open-Label Induction Cohort of the Phase 3... von Peyrin-Biroulet, Laurent, Feagan, Brian G., Mansfield, John, Rubin, David T., Arulmani, Udayasankar, Maciuca, Romeo, Tyrrell, Helen, Thommes, James, Tole, Swati

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20 ETROLIZUMAB IMPROVED ENDOSCOPIC SCORE, PATIENT-REPORTED OUTCOMES, AND INFLAMMATORY BIOMARKERS IN PATIENTS WITH MODERATE TO SEVERE UC WHO HAD FAILED TNF ANTAGONIST THERAPY: THE H... von Peyrin-Biroulet, Laurent, Rubin, David T, Feagan, Brian, Oh, Young S, Arulmani, Udayasankar, Tyrrell, Helen, Maciuca, Romeo, Williams, Sarah, Tole, Swati, Thommes, James

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Etrolizumab Treatment Leads to Early Improvement in Symptoms and Inflammatory Biomarkers in Anti-Tnfrefractory Patients in the Open-Label Induction Cohort of the Phase 3 Hickory St... von Peyrin-Biroulet, Laurent, Feagan, Brian G, Mansfield, John, Rubin, David T, Arulmani, Udayasankar, Maciuca, Romeo, Tyrrell, Helen, Thommes, James, Tole, Swati

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Dual targeting of lymphocyte homing and retention through α4β7 and αEβ7 inhibition in inflammatory bowel disease von Dai, Bingbing, Hackney, Jason A., Ichikawa, Ryan, Nguyen, Allen, Elstrott, Justin, Orozco, Luz D., Sun, Kai-Hui, Modrusan, Zora, Gogineni, Alvin, Scherl, Alexis, Gubatan, John, Habtezion, Aida, Deswal, Monika, Somsouk, Ma, Faubion, William A., Chai, Akiko, Sharafali, Zaineb, Hassanali, Azra, Oh, Young S., Tole, Swati, McBride, Jacqueline, Keir, Mary E., Yi, Tangsheng

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Inflammatory Bowel Disease Patients' Perspectives of Clinical Trials: A Global Quantitative and Qualitative Analysis von Rubin, David T, Peyrin-Biroulet, Laurent, Reinisch, Walter, Tole, Swati, Sullivan, Laura, Park, K T, Regueiro, Miguel

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