A high-throughput imaging and nuclear segmentation analysis protocol for cleared 3D culture models von Boutin, Molly E., Voss, Ty C., Titus, Steven A., Cruz-Gutierrez, Kennie, Michael, Sam, Ferrer, Marc

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A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity von Yasgar, Adam, Titus, Steven A, Wang, Yuhong, Danchik, Carina, Yang, Shyh-Ming, Vasiliou, Vasilis, Jadhav, Ajit, Maloney, David J, Simeonov, Anton, Martinez, Natalia J

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A Comprehensive Phenotypic Screening Strategy to Identify Modulators of Cargo Translocation by the Bacterial Type IVB Secretion System von Cheng, Eric, Dorjsuren, Dorjbal, Lehman, Stephanie, Larson, Charles L, Titus, Steven A, Sun, Hongmao, Zakharov, Alexey, Rai, Ganesha, Heinzen, Robert A, Simeonov, Anton, Machner, Matthias P

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Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein von Al-Ramahi, Ismael, Giridharan, Sai Srinivas Panapakkam, Chen, Yu-Chi, Patnaik, Samarjit, Safren, Nathaniel, Hasegawa, Junya, de Haro, Maria, Wagner Gee, Amanda K, Titus, Steven A, Jeong, Hyunkyung, Clarke, Jonathan, Krainc, Dimitri, Zheng, Wei, Irvine, Robin F, Barmada, Sami, Ferrer, Marc, Southall, Noel, Weisman, Lois S, Botas, Juan, Marugan, Juan Jose

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Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity von Yasgar, Adam, Titus, Steven A, Wang, Yuhong, Danchik, Carina, Yang, Shyh-Ming, Vasiliou, Vasilis, Jadhav, Ajit, Maloney, David J, Simeonov, Anton, Martinez, Natalia J

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Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5 von Stephen, Joshi, Yokoyama, Tadafumi, Tolman, Nathanial J, O'Brien, Kevin J, Nicoli, Elena-Raluca, Brooks, Brian P, Huryn, Laryssa, Titus, Steven A, Adams, David R, Chen, Dong, Gahl, William A, Gochuico, Bernadette R, Malicdan, May Christine V

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A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel von Titus, Steven A., Beacham, Daniel, Shahane, Sampada A., Southall, Noel, Xia, Menghang, Huang, Ruili, Hooten, Elizabeth, Zhao, Yong, Shou, Louie, Austin, Christopher P., Zheng, Wei

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Concerted assembly and cloning of multiple DNA segments using in vitro site-specific recombination: functional analysis of multi-segment expression clones von Cheo, David L, Titus, Steven A, Byrd, Devon R N, Hartley, James L, Temple, Gary F, Brasch, Michael A

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Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors von Skoumbourdis, Amanda P., LeClair, Christopher A., Stefan, Eduard, Turjanski, Adrian G., Maguire, William, Titus, Steven A., Huang, Ruili, Auld, Douglas S., Inglese, James, Austin, Christopher P., Michnick, Stephen W., Xia, Menghang, Thomas, Craig J.

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SNARE-Complex Disassembly by NSF Follows Synaptic-Vesicle Fusion von Littleton, J. Troy, Richard J. O. Barnard, Titus, Steven A., Slind, Jessica, Chapman, Edwin R., Ganetzky, Barry

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A Mutation Inactivating the Mitochondrial Inner Membrane Folate Transporter Creates a Glycine Requirement for Survival of Chinese Hamster Cells von McCarthy, Erin A., Titus, Steven A., Taylor, Shirley M., Jackson-Cook, Colleen, Moran, Richard G.

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Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays von Crowe, Alex, Henderson, Mark J., Anderson, Johnathon, Titus, Steven A., Zakharov, Alexey, Simeonov, Anton, Buist, Arjan, Delay, Charlotte, Moechars, Diederik, Trojanowski, John Q., Lee, Virginia M.-Y., Brunden, Kurt R.

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Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays von Urban, Daniel J., Martinez, Natalia J., Davis, Mindy I., Brimacombe, Kyle R., Cheff, Dorian M., Lee, Tobie D., Henderson, Mark J., Titus, Steven A., Pragani, Rajan, Rohde, Jason M., Liu, Li, Fang, Yuhong, Karavadhi, Surendra, Shah, Pranav, Lee, Olivia W., Wang, Amy, McIver, Andrew, Zheng, Hongchao, Wang, Xiaodong, Xu, Xin, Jadhav, Ajit, Simeonov, Anton, Shen, Min, Boxer, Matthew B., Hall, Matthew D.

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High-Throughput Zika Viral Titer Assay for Rapid Screening of Antiviral Drugs von Lee, Emily M, Titus, Steven A, Xu, Miao, Tang, Hengli, Zheng, Wei

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Mammalian Mitochondrial and Cytosolic Folylpolyglutamate Synthetase Maintain the Subcellular Compartmentalization of Folates von Lawrence, Scott A., Titus, Steven A., Ferguson, Jennifer, Heineman, Amy L., Taylor, Shirley M., Moran, Richard G.

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A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets von Klanert, Gerald, Fernandez, Daniel J., Weinguny, Marcus, Eisenhut, Peter, Bühler, Eugen, Melcher, Michael, Titus, Steven A., Diendorfer, Andreas B., Gludovacz, Elisabeth, Jadhav, Vaibhav, Xiao, Su, Stern, Beate, Lal, Madhu, Shiloach, Joseph, Borth, Nicole

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Lung tumor microphysiological system with 3D endothelium to evaluate modulators of T-cell migration von Wisdom, Katrina M, Suijker, Johnny, van den Broek, Lenie, Sridharan, BanuPriya, Grandhi, Taraka Sai Pavan, Cheng, Aaron, Lamb, Mahdi, Titus, Steven A, Poore, Derek, Shah, Niyant, Cheng, Shih-Hsun, Kim, Edward, Griffin, Sue, Ekert, Jason

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Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington’s Disease Model through the Application of Quantitative Systems Pharmacology von Pei, Fen, Li, Hongchun, Henderson, Mark J., Titus, Steven A., Jadhav, Ajit, Simeonov, Anton, Cobanoglu, Murat Can, Mousavi, Seyed H., Shun, Tongying, McDermott, Lee, Iyer, Prema, Fioravanti, Michael, Carlisle, Diane, Friedlander, Robert M., Bahar, Ivet, Taylor, D. Lansing, Lezon, Timothy R., Stern, Andrew M., Schurdak, Mark E.

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Exploring Drug Dosing Regimens In Vitro Using Real-Time 3D Spheroid Tumor Growth Assays von Lal-Nag, Madhu, McGee, Lauren, Titus, Steven A., Brimacombe, Kyle, Michael, Sam, Sittampalam, Gurusingham, Ferrer, Marc

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Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels von Xia, Menghang, Shahane, Sampada A., Huang, Ruili, Titus, Steven A., Shum, Enoch, Zhao, Yong, Southall, Noel, Zheng, Wei, Witt, Kristine L., Tice, Raymond R., Austin, Christopher P.

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