NTRK fusion in soft tissue sarcomas harboring MDM2/CDK4 amplification: three case reports von Brahmi, M., Dufresne, A., Verret, B., Tirode, F., Blay, J.Y.

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Complete response to CSF1R inhibitor in a translocation variant of teno-synovial giant cell tumor without genomic alteration of the CSF1 gene von Brahmi, M., Alberti, L., Tirode, F., Karanian, M., Eberst, L., Pissaloux, D., Cassier, P., Blay, J.Y.

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An orbital perivascular epithelioid cell tumor (PEComa) in a 9-year-old boy: Case report and review of the literature von Bouzid, N., Bugada, M., Pissaloux, D., Burillon, C., Tirode, F., Barbier, J., de la Fouchardière, A., Kielwasser, G.

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Natural history and treatment efficacy in an ambispective case series of NTRK-rearranged mesenchymal tumors von Dufresne, A., Pissaloux, D., Ngo, C., Penel, N., Le Cesne, A., Macagno, N., Vanacker, H., Hénon, C., Jean-Denis, M., Rughoo, K., Tirode, F., Blay, J.-Y., Brahmi, M.

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Update on gene fusions and the emerging clinicopathological landscape of peritoneal and pleural mesotheliomas and other neoplasms von Benzerdjeb, N., Dartigues, P., Kepenekian, V., Damiola, F., Sequeiros, R., Galateau-Salle, F., Begueret, H., Mery, E., Damotte, D., Verriele, V., Fontaine, J., Isaac, S., Valmary-Degano, S., Villeneuve, L., Glehen, O., Scherpereel, A., Forest, F., De la Fourchardiere, A., Paindavoine, S., Hourlier, A., Pissaloux, D., Tirode, F., Lantuejoul, S.

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Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage von Alsafadi, S, Houy, A, Battistella, A, Popova, T, Wassef, M, Henry, E, Tirode, F, Constantinou, A, Piperno-Neumann, S, Roman-Roman, S, Dutertre, M, Stern, M.H

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Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage von Alsafadi, Samar, Houy, Alexandre, Battistella, Aude, Popova, Tatiana, Wassef, Michel, Henry, Emilie, Tirode, Franck, Constantinou, Angelos, Piperno-Neumann, Sophie, Roman-Roman, Sergio, Dutertre, Martin, Stern, Marc-Henri

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648 Identification of Shortened 3 Untranslated Regions and Impact on MicroRNA Regulation von Martignetti, L, Laud-Duval, K, Tirode, F, Barillot, E, Delattre, O, Zinovyev, A

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Mesenchymal Stem Cell Features of Ewing Tumors von Tirode, Franck, Laud-Duval, Karine, Prieur, Alexandre, Delorme, Bruno, Charbord, Pierre, Delattre, Olivier

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Transcriptional inhibition of connexin 43 BY EWS-FLI1: Implication in tumor development of ewing's sarcoma von Talbot, J, Picarda, G, Amiaud, J, Chesneau, J, Brion, R, Tirode, F, Heymann, D, Redini, F, Verrecchia, F

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Oncostatin M is a growth factor for ewing sarcoma: Potent role of the leukemia inhibitory factor receptor von David, E, Guihard, P, Tirode, F, Laud, K, Delattre, O, Heymann, D, Redini, F, Blanchard, F

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EWS/FLI-1 Silencing and Gene Profiling of Ewing Cells Reveal Downstream Oncogenic Pathways and a Crucial Role for Repression of Insulin-Like Growth Factor Binding Protein 3 von Prieur, Alexandre, Tirode, Franck, Cohen, Pinchas, Delattre, Olivier

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6MO Pan-cancer characterization of receptor tyrosine kinases alterations to sort targetable drivers from passengers von Vanacker, H., Attignon, V.K., Brahmi, M., Dufresne, A., Cassier, P., Carbonnaux, M., Pissaloux, D., Boyault, S., Wang, Q.L., Tredan, O., Tirode, F., Blay, J-Y.

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1921MO Patterns of care, outcome and molecular landscape of PATZ1-rearranged sarcomas identifies two prognostic profiles: A cohort study from the French Sarcoma Group (FSG) von Vanacker, H., Le Loarer, F., Karanian, M., Meurgey, A., Dufresne, A., El Zein, S., Blay, J-Y., Collard, O., Ray-Coquard, I.L., Waissi, W.A., Pissaloux, D., Paindavoine, S., Houlier, A., Pierron, G., Meeus, P., Tirode, F., Brahmi, M.

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1975P Systemic therapy for KIT/PDGFRA wild-type GIST von Brahmi, M., Dufresne, A., Pattee, A., Vanacker, H., Meurgey, A., Pissaloux, D., Meeus, P., Sunyach, M-P., Karanian, M., Bouhamama, A., Tirode, F., Cassier, P., Ray-Coquard, I.L., Blay, J-Y.

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Preclinical evidence of using TRAIL in Ewing's sarcoma therapy von Picarda, G, Lamoureux, F, Geffroy, L, Delepine, P, Laud, K, Burchill, S, Tirode, F, Delattre, O, Heymann, D, Redini, F

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Zoledronic acid as new adjuvant therapeutic agent for Ewing's sarcoma von Odri, G.A, Lamoureux, F, Picarda, G, Dumoucel, S, Battaglia, S, Trichet, V, Laud, K, Tirode, F, Burchill, S, Delattre, O, Gouin, F, Heymann, D, Redini, F

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1534P Patterns of care and outcomes of NTRK-fusion positive sarcomas: A retrospective and prospective cases series von Dufresne, A., Lebellec, L., Karanian, M., Pissaloux, D., Tirode, F., Corradini, N., Rughoo, K., Cassier, P.A., Meeus, P., Sunyach, M.P., Gouin, F., Ray-Coquard, I.L., Blay, J-Y., Penel, N., Mehdi, B.

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1716P - The molecular landscape of fusion genes in endometrial stromal sarcomas include three nosological entities with different natural history von Brahmi, M., Franceschi, T., Treilleux, I., Pissaloux, D., Ray-Coquard, I.L., Dufresne, A., Meeus, P., Sunyach, M.-P., Marie, K., Meurgey, A., Blay, J.-Y., Tirode, F.

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The molecular landscape of fusion genes in endometrial stromal sarcomas include three nosological entities with different natural history von Brahmi, M., Franceschi, T., Treilleux, I., Pissaloux, D., Ray-Coquard, I.L., Dufresne, A., Meeus, P., Sunyach, M.-P., Marie, K., Meurgey, A., Blay, J.-Y., Tirode, F.

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