Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity von Maurer, Till, Garrenton, Lindsay S, Oh, Angela, Pitts, Keith, Anderson, Daniel J, Skelton, Nicholas J, Fauber, Benjamin P, Pan, Borlan, Malek, Shiva, Stokoe, David, Ludlam, Mary J. C, Bowman, Krista K, Wu, Jiansheng, Giannetti, Anthony M, Starovasnik, Melissa A, Mellman, Ira, Jackson, Peter K, Rudolph, Joachim, Wang, Weiru, Fang, Guowei

Volltext

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes von Hewings, David S., Heideker, Johanna, Ma, Taylur P., AhYoung, Andrew P., El Oualid, Farid, Amore, Alessia, Costakes, Gregory T., Kirchhofer, Daniel, Brasher, Bradley, Pillow, Thomas, Popovych, Nataliya, Maurer, Till, Schwerdtfeger, Carsten, Forrest, William F., Yu, Kebing, Flygare, John, Bogyo, Matthew, Wertz, Ingrid E.

Volltext

Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation von Rougé, Lionel, Bainbridge, Travis W., Kwok, Michael, Tong, Raymond, Di Lello, Paola, Wertz, Ingrid E., Maurer, Till, Ernst, James A., Murray, Jeremy

Volltext

Backbone cyclization of a recombinant cystine-knot peptide by engineered Sortase A von Stanger, Karen, Maurer, Till, Kaluarachchi, Harini, Coons, Mary, Franke, Yvonne, Hannoush, Rami N.

Volltext

Advancing Fragment Binders to Lead-Like Compounds Using Ligand and Protein-Based NMR Spectroscopy von Maurer, Till

Volltext

USP7 small-molecule inhibitors interfere with ubiquitin binding von Kategaya, Lorna, Di Lello, Paola, Rougé, Lionel, Pastor, Richard, Clark, Kevin R., Drummond, Jason, Kleinheinz, Tracy, Lin, Eva, Upton, John-Paul, Prakash, Sumit, Heideker, Johanna, McCleland, Mark, Ritorto, Maria Stella, Alessi, Dario R., Trost, Matthias, Bainbridge, Travis W., Kwok, Michael C. M., Ma, Taylur P., Stiffler, Zachary, Brasher, Bradley, Tang, Yinyan, Jaishankar, Priyadarshini, Hearn, Brian R., Renslo, Adam R., Arkin, Michelle R., Cohen, Frederick, Yu, Kebing, Peale, Frank, Gnad, Florian, Chang, Matthew T., Klijn, Christiaan, Blackwood, Elizabeth, Martin, Scott E., Forrest, William F., Ernst, James A., Ndubaku, Chudi, Wang, Xiaojing, Beresini, Maureen H., Tsui, Vickie, Schwerdtfeger, Carsten, Blake, Robert A., Murray, Jeremy, Maurer, Till, Wertz, Ingrid E.

Volltext

Structural basis for dual-mode inhibition of the ABC transporter MsbA von Ho, Hoangdung, Miu, Anh, Alexander, Mary Kate, Garcia, Natalie K., Oh, Angela, Zilberleyb, Inna, Reichelt, Mike, Austin, Cary D., Tam, Christine, Shriver, Stephanie, Hu, Huiyong, Labadie, Sharada S., Liang, Jun, Wang, Lan, Wang, Jian, Lu, Yan, Purkey, Hans E., Quinn, John, Franke, Yvonne, Clark, Kevin, Beresini, Maureen H., Tan, Man-Wah, Sellers, Benjamin D., Maurer, Till, Koehler, Michael F. T., Wecksler, Aaron T., Kiefer, James R., Verma, Vishal, Xu, Yiming, Nishiyama, Mireille, Payandeh, Jian, Koth, Christopher M.

Volltext

Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin von Ultsch, Mark, Li, Bing, Maurer, Till, Mathieu, Mary, Adolfsson, Oskar, Muhs, Andreas, Pfeifer, Andrea, Pihlgren, Maria, Bainbridge, Travis W., Reichelt, Mike, Ernst, James A., Eigenbrot, Charles, Fuh, Germaine, Atwal, Jasvinder K., Watts, Ryan J., Wang, Weiru

Volltext

Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques von Di Lello, Paola, Pastor, Richard, Murray, Jeremy M, Blake, Robert A, Cohen, Frederick, Crawford, Terry D, Drobnick, Joy, Drummond, Jason, Kategaya, Lorna, Kleinheinz, Tracy, Maurer, Till, Rougé, Lionel, Zhao, Xianrui, Wertz, Ingrid, Ndubaku, Chudi, Tsui, Vickie

Volltext

Length Matters: MINDY Is a New Deubiquitinase Family that Preferentially Cleaves Long Polyubiquitin Chains von Maurer, Till, Wertz, Ingrid E.

Volltext

A restraint molecular dynamics and simulated annealing approach for protein homology modeling utilizing mean angles von Möglich, Andreas, Weinfurtner, Daniel, Maurer, Till, Gronwald, Wolfram, Kalbitzer, Hans Robert

Volltext

Cellular uptake of a cystine-knot peptide and modulation of its intracellular trafficking von Gao, Xinxin, Stanger, Karen, Kaluarachchi, Harini, Maurer, Till, Ciepla, Paulina, Chalouni, Cecile, Franke, Yvonne, Hannoush, Rami N.

Volltext

High-Resolution Structure of the Histidine-Containing Phosphocarrier Protein (HPr) from Staphylococcus aureus and Characterization of Its Interaction with the Bifunctional HPr Kina... von MAURER, Till, MEIER, Sebastian, KACHEL, Norman, MUNTE, Claudia Elisabeth, HASENBEIN, Sonja, KOCH, Brigitte, HENGSTENBERG, Wolfgang, KALBITZER, Hans Robert

Volltext

Combined chemical shift changes and amino acid specific chemical shift mapping of protein-protein interactions von Schumann, Frank H, Riepl, Hubert, Maurer, Till, Gronwald, Wolfram, Neidig, Klaus-Peter, Kalbitzer, Hans Robert

Volltext

De Novo Guanine Biosynthesis but Not the Riboswitch-Regulated Purine Salvage Pathway Is Required for Staphylococcus aureus Infection In Vivo von Kofoed, Eric M, Yan, Donghong, Katakam, Anand K, Reichelt, Mike, Lin, Baiwei, Kim, Janice, Park, Summer, Date, Shailesh V, Monk, Ian R, Xu, Min, Austin, Cary D, Maurer, Till, Tan, Man-Wah

Volltext

Phosphorylation-dependent activity of the deubiquitinase DUBA von Huang, Oscar W, Ma, Xiaolei, Yin, JianPing, Flinders, Jeremy, Maurer, Till, Kayagaki, Nobuhiko, Phung, Qui, Bosanac, Ivan, Arnott, David, Dixit, Vishva M, Hymowitz, Sarah G, Starovasnik, Melissa A, Cochran, Andrea G

Volltext

Cellular uptake of a cystine‐knot peptide and modulation of its intracellular trafficking von Gao, Xinxin, Stanger, Karen, Kaluarachchi, Harini, Maurer, Till, Ciepla, Paulina, Chalouni, Cecile, Franke, Yvonne, Hannoush, Rami N

Volltext

NMR Studies of Protein–Ligand Interactions von Maurer, Till

Volltext

Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation von Rougé, Lionel, Bainbridge, Travis W., Kwok, Michael, Tong, Raymond, Di Lello, Paola, Wertz, Ingrid E., Maurer, Till, Ernst, James A., Murray, Jeremy

Volltext

(1)H, (13)C and (15)N backbone resonance assignment for the 40.5 kDa catalytic domain of Ubiquitin Specific Protease 7 (USP7) von Di Lello, Paola, Rougé, Lionel, Pan, Borlan, Maurer, Till

Volltext