Emerging roles of lysophosphatidic acid receptor subtype 5 (LPAR5) in inflammatory diseases and cancer von Dacheux, Mélanie A., Norman, Derek D., Tigyi, Gábor J., Lee, Sue Chin

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The transcription factor CREB enhances interleukin-17A production and inflammation in a mouse model of atherosclerosis von Kotla, Sivareddy, Singh, Nikhlesh K, Heckle, Mark R, Tigyi, Gabor J, Rao, Gadiparthi N

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A reflection of the lasting contributions from Dr. Robert Bittman to sterol trafficking, sphingolipid and phospholipid research von Pyne, Nigel J., Tigyi, Gabor J.

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PLD1-dependent PKCγ activation downstream to Src is essential for the development of pathologic retinal neovascularization von Zhang, Qiuhua, Wang, Dong, Kundumani-Sridharan, Venkatesh, Gadiparthi, Laxmisilpa, Johnson, Dianna A., Tigyi, Gabor J., Rao, Gadiparthi N.

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Designing Dual Inhibitors of Autotaxin-LPAR GPCR Axis von Banerjee, Souvik, Lee, Suechin, Norman, Derek D, Tigyi, Gabor J

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Role of the autotaxin–lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy von Brindley, David N., Lin, Fang-Tsyr, Tigyi, Gabor J.

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Optical control of sphingosine-1-phosphate formation and function von Morstein, Johannes, Hill, Rose Z., Novak, Alexander J. E., Feng, Suihan, Norman, Derek D., Donthamsetti, Prashant C., Frank, James A., Harayama, Takeshi, Williams, Benjamin M., Parrill, Abby L., Tigyi, Gabor J., Riezman, Howard, Isacoff, Ehud Y., Bautista, Diana M., Trauner, Dirk

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Highly Potent Non-Carboxylic Acid Autotaxin Inhibitors Reduce Melanoma Metastasis and Chemotherapeutic Resistance of Breast Cancer Stem Cells von Banerjee, Souvik, Norman, Derek D, Lee, Sue Chin, Parrill, Abby L, Pham, Truc Chi T, Baker, Daniel L, Tigyi, Gabor J, Miller, Duane D

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LPA suppresses HLA-DR expression in human melanoma cells: a potential immune escape mechanism involving LPAR1 and DR6-mediated release of IL-10 von Major, Enikő, Lin, Kuan-Hung, Lee, Sue Chin, Káldi, Krisztina, Győrffy, Balázs, Tigyi, Gábor J., Benyó, Zoltán

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Regulation of tumor cell – Microenvironment interaction by the autotaxin-lysophosphatidic acid receptor axis von Tigyi, Gabor J., Yue, Junming, Norman, Derek D., Szabo, Erzsebet, Balogh, Andrea, Balazs, Louisa, Zhao, Guannan, Lee, Sue Chin

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Lysophosphatidic acid type 2 receptor agonists in targeted drug development offer broad therapeutic potential von Tigyi, Gabor J., Johnson, Leonard R., Lee, Sue Chin, Norman, Derek D., Szabo, Erzsebet, Balogh, Andrea, Thompson, Karin, Boler, Alyssa, McCool, W. Shannon

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Autotaxin and LPA1 and LPA5 receptors exert disparate functions in tumor cells versus the host tissue microenvironment in melanoma invasion and metastasis von Lee, Sue-Chin, Fujiwara, Yuko, Liu, Jianxiong, Yue, Junming, Shimizu, Yoshibumi, Norman, Derek D, Wang, Yaohong, Tsukahara, Ryoko, Szabo, Erzsebet, Patil, Renukadevi, Banerjee, Souvik, Miller, Duane D, Balazs, Louisa, Ghosh, Manik C, Waters, Christopher M, Oravecz, Tamas, Tigyi, Gabor J

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Deleting autotaxin in LysM+ myeloid cells impairs innate tumor immunity in models of metastatic melanoma von Dacheux, Mélanie A., Norman, Derek D., Shin, Yoojin, Tigyi, Gábor J., Lee, Sue Chin

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Lysophosphatidic acid induces proliferation and osteogenic differentiation of human dental pulp stem cell through lysophosphatidic acid receptor 3/extracellular signal-regulated ki... von Heo, Soon Chul, Keum, Bo Ram, Seo, Eun Jin, Yoon, Jinhwan, Jeong, Sanghwa, Tigyi, Gabor J., Norman, Derek, Jang, Il Ho, Kim, Hyung Joon

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Prometastatic Effect of ATX Derived from Alveolar Type II Pneumocytes and B16-F10 Melanoma Cells von Dacheux, Mélanie A, Lee, Sue Chin, Shin, Yoojin, Norman, Derek D, Lin, Kuan-Hung, E, Shuyu, Yue, Junming, Benyó, Zoltán, Tigyi, Gábor J

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Uncovering unique roles of LPA receptors in the tumor microenvironment von Lee, Sue-Chin, Fujiwara, Yuko, Tigyi, Gabor J.

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Mitigation of the Hematopoietic and Gastrointestinal Acute Radiation Syndrome by Octadecenyl Thiophosphate, a Small Molecule Mimic of Lysophosphatidic Acid von Deng, Wenlin, Kimura, Yasuhiro, Gududuru, Veeresh, Wu, Wenjie, Balogh, Andrea, Szabo, Erzsebet, Thompson, Karin Emmons, Yates, C. Ryan, Balazs, Louisa, Johnson, Leonard R., Miller, Duane D., Strobos, Jur, McCool, W. Shannon, Tigyi, Gabor J.

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Autotaxin delays apoptosis induced by carboplatin in ovarian cancer cells von Vidot, Susanne, Witham, James, Agarwal, Roshan, Greenhough, Sebastian, Bamrah, Harnoor S., Tigyi, Gabor J., Kaye, Stanley B., Richardson, Alan

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Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions von Li, Chunying, Dandridge, Keanna S, Di, Anke, Marrs, Kevin L, Harris, Erica L, Roy, Koushik, Jackson, John S, Makarova, Natalia V, Fujiwara, Yuko, Farrar, Patricia L, Nelson, Deborah J, Tigyi, Gabor J, Naren, Anjaparavanda P

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Interaction of platelet-derived autotaxin with tumor integrin αVβ3 controls metastasis of breast cancer cells to bone von Leblanc, Raphael, Lee, Sue-Chin, David, Marion, Bordet, Jean-Claude, Norman, Derek D., Patil, Renukadevi, Miller, Duane, Sahay, Debashish, Ribeiro, Johnny, Clézardin, Philippe, Tigyi, Gabor J., Peyruchaud, Olivier

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