Exosomal delivery of doxorubicin enables rapid cell entry and enhanced in vitro potency von Schindler, Christina, Collinson, Andie, Matthews, Carl, Pointon, Amy, Jenkinson, Lesley, Minter, Ralph R, Vaughan, Tristan J, Tigue, Natalie J

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Overcoming the Refractory Expression of Secreted Recombinant Proteins in Mammalian Cells through Modification of the Signal Peptide and Adjacent Amino Acids von Güler-Gane, Gülin, Kidd, Sara, Sridharan, Sudharsan, Vaughan, Tristan J, Wilkinson, Trevor C I, Tigue, Natalie J

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A simeprevir-inducible molecular switch for the control of cell and gene therapies von Chin, Stacey E., Schindler, Christina, Vinall, Lisa, Dodd, Roger B., Bamber, Lisa, Legg, Sandrine, Sigurdardottir, Anna, Rees, D. Gareth, Malcolm, Tim I. M., Spratley, Samantha J., Granéli, Cecilia, Sumner, Jonathan, Tigue, Natalie J.

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MEDI1873, a potent, stabilized hexameric agonist of human GITR with regulatory T-cell targeting potential von Tigue, Natalie J., Bamber, Lisa, Andrews, John, Ireland, Samantha, Hair, James, Carter, Edward, Sridharan, Sudharsan, Jovanović, Jelena, Rees, D. Gareth, Springall, Jeremy S., Solier, Emilie, Li, Yi-Ming, Chodorge, Matthieu, Perez-Martinez, David, Higazi, Daniel R., Oberst, Michael, Kennedy, Maureen, Black, Chelsea M., Yan, Li, Schwickart, Martin, Maguire, Shaun, Cann, Jennifer A., de Haan, Lolke, Young, Lesley L., Vaughan, Tristan, Wilkinson, Robert W., Stewart, Ross

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MHC class I chain-related protein A and B (MICA and MICB) are predominantly expressed intracellularly in tumour and normal tissue von Ghadially, Hormas, Brown, Lee, Lloyd, Chris, Lewis, Leeanne, Lewis, Arthur, Dillon, Janette, Sainson, Richard, Jovanovic, Jelena, Tigue, Natalie J, Bannister, David, Bamber, Lisa, Valge-Archer, Viia, Wilkinson, Robert W

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A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist von Leyland, Rebecca, Watkins, Amanda, Mulgrew, Kathy A, Holoweckyj, Nicholas, Bamber, Lisa, Tigue, Natalie J, Offer, Emily, Andrews, John, Yan, Li, Mullins, Stefanie, Oberst, Michael D, Coates Ulrichsen, Jane, Leinster, David A, McGlinchey, Kelly, Young, Lesley, Morrow, Michelle, Hammond, Scott A, Mallinder, Philip, Herath, Athula, Leow, Ching Ching, Wilkinson, Robert W, Stewart, Ross

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The α-Helix 4 Residue, Asn135, Is Involved in the Oligomerization of Cry1Ac1 and Cry1Ab5 Bacillus thuringiensis Toxins von TIGUE, Natalie J, JACOBY, Juliette, ELLAR, David J

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Use of the Site-Specific Retargeting Jump-In Platform Cell Line to Support Biologic Drug Discovery von Butler, Robin, Hornigold, David, Huang, Ling, Huntington, Catherine, London, Tim, Dillon, Janette, Tigue, Natalie J., Rossi, Alessandra, Naylor, Jacqueline, Wilkinson, Trevor

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Abstract 4902: A mouse GITRL fusion protein drives T-cell activation and antitumor activity in preclinical mouse models of cancer von Leyland, Rebecca, Watkins, Amanda, Mulgrew, Kathy A., Bamber, Lisa, Tigue, Natalie J., Dick, Emily, Holoweckyj, Nick, Young, Lesley, Morrow, Michelle, Hammond, Scott A., Leow, Ching Ching, Wilkinson, Robert W., Stewart, Ross

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Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope "tags" von Percival-Alwyn, Jennifer L, England, Elizabeth, Kemp, Benjamin, Rapley, Laura, Davis, Nicola H E, McCarthy, Grant R, Majithiya, Jayesh B, Corkill, Dominic J, Welsted, Sarah, Minton, Kevin, Cohen, E Suzanne, Robinson, Matthew J, Dobson, Claire, Wilkinson, Trevor C I, Vaughan, Tristan J, Groves, Maria A T, Tigue, Natalie J

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Characterisation of recombinant rat TRPM2 and a TRPM2-like conductance in cultured rat striatal neurones von Hill, Kerstin, Tigue, Natalie J., Kelsell, Rosemary E., Benham, Christopher D., McNulty, Shaun, Schaefer, Michael, Randall, Andrew D.

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Autoprocessing and Peptide Substrates for Human Herpesvirus 6 Proteinase von Tigue, Natalie J., Kay, John

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Active site mutants of human herpesvirus-6 proteinase von Tigue, Natalie J, Kay, John

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The alpha-helix residue, Asn135, is involved in the oligomerization of Cry1Ac1 and Cry1Ab5 Bacillus thuringiensis toxins von Tigue, Natalie J, Jacoby, Juliette, Ellar, David J

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Cloning, expression and characterization of the proteinase from human herpesvirus 6 von Tigue, N J, Matharu, P J, Roberts, N A, Mills, J S, Kay, J, Jupp, R

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Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope "tags" von Percival-Alwyn, Jennifer L, England, Elizabeth, Kemp, Benjamin, Rapley, Laura, Davis, Nicola HE, McCarthy, Grant R, Majithiya, Jayesh B, Corkill, Dominic J, Welsted, Sarah, Minton, Kevin, Cohen, E Suzanne, Robinson, Matthew J, Dobson, Claire, Wilkinson, Trevor CI, Vaughan, Tristan J, Groves, Maria AT, Tigue, Natalie J

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GITRL FUSION PROTEINS AND USES THEREOF von BAMBER, LISA, DURHAM, NICHOLAS MASON, TIGUE, NATALIE JO, YOUNG, LESLEY LYNN, SRIDHARAN, SUDHARSAN, STEWART, ROSS ANTHONY, HIGAZI, DANIEL RAMSAY, LEYLAND, REBECCA

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GITRL FUSION PROTEINS AND USES THEREOF von STEWART ROSS ANTHONY, YOUNG LESLEY LYNN, TIGUE NATALIE JO, HIGAZI DANIEL RAMSAY, DURHAM NICHOLAS MASON, LEYLAND REBECCA, SRIDHARAN SUDHARSAN, BAMBER LISA

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ＧＩＴＲＬ 융합 단백질 및 그의 용도 von STEWART ROSS ANTHONY, YOUNG LESLEY LYNN, TIGUE NATALIE JO, HIGAZI DANIEL RAMSAY, DURHAM NICHOLAS MASON, LEYLAND REBECCA, SRIDHARAN SUDHARSAN, BAMBER LISA

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GITRL fusion proteins and uses thereof von BAMBER, LISA, DURHAM, NICHOLAS MASON, TIGUE, NATALIE JO, YOUNG, LESLEY LYNN, SRIDHARAN, SUDHARSAN, STEWART, ROSS ANTHONY, HIGAZI, DANIEL RAMSAY, LEYLAND, REBECCA

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