Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells von Moulding, Dale A., Giles, Richard V., Spiller, David G., White, Michael R.H., Tidd, David M., Edwards, Steven W.

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Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells von Giles, R. V., Spiller, D. G., Grzybowski, J., Clark, R. E., Nicklin, P., Tidd, D. M.

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CpG oligodeoxynucleotide 5mer‐induced apoptosis in MOLT‐4 leukaemia cells does not require caspase 3 or new protein synthesis von Tidd, David M., Broughton, Caroline M., Clark, Richard E.

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Optimization of Antisense Oligodeoxynucleotide Structure for Targeting bcr-abl mRNA von Giles, R.V., Spiller, D.G., Green, J.A., Clark, R.E., Tidd, D.M.

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Partial protection of oncogene, anti-sense oligodeoxynucleotides against serum nuclease degradation using terminal methylphosphonate groups von TIDD, D. M, WARENIUS, H. M

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Oligodeoxynucleotide 5mers containing a 5'-CpG induce apoptosis through a mitochondrial mechanism in T lymphocytic leukaemia cells von Tidd, D M, Spiller, D G, Broughton, C M, Norbury, L C, Clark, R E, Giles, R V

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Clinical use of streptolysin-O to facilitate antisense oligodeoxyribonucleotide delivery for purging autografts in chronic myeloid leukaemia von CLARK, R. E, GRZYBOWSKI, J, BROUGHTON, C. M, PENDER, N. T, SPILLER, D. G, BRAMMER, C. G, GILES, R. V, TIDD, D. M

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Preclinical studies of streptolysin-O in enhancing antisense oligonucleotide uptake in harvests from chronic myeloid leukaemia patients von BROUGHTON, C. M, SPILLER, D. G, PENDER, N, KOMOROVSKAYA, M, GRZYBOWSKI, J, GILES, R. V, TIDD, D. M, CLARK, R. E

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Synthetic oligonucleotides as therapeutic agents von TIDD, D. M

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Determination of optimal sites of antisense oligonucleotide cleavage within TNFα mRNA von Lloyd, B. H., Giles, R. V., Spiller, D. G., Grzybowski, J., Tidd, D. M., Sibson, D. R.

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Increased specificity for antisense oligodeoxynucleotide targeting of RNA cleavage by RNase H using chimeric methylphosphonodiester/phosphodiester structures von Giles, Richard V., Tidd, David M.

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Multigrid Euler calculations over complete aircraft von Tidd, D. M, Strash, D. J, Epstein, B, Luntz, A, Nachshon, A, Rubin, T

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Single base discrimination for ribonuclease H-dependent antisense effects within intact human leukaemia cells von Giles, Richard V., Ruddell, Carolyn J., Spiller, David G., Green, John A., Tidd, David M.

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Abrogation of c-MYC protein degradation in human lymphocyte lysates by prior precipitation with perchloric acid von Spiller, D.G., Tidd, D.M.

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The free surface flow of Newtonian and non-Newtonian fluids trapped by surface tension von Tidd, D. M., Thatcher, R. W., Kaye, A.

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Improving the Intracellular Delivery and Molecular Efficacy of Antisense Oligonucleotides in Chronic Myeloid Leukemia Cells: A Comparison of Streptolysin-O Permeabilization, Electr... von Spiller, David G., Giles, Richard V., Grzybowski, John, Tidd, David M., Clark, Richard E.

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Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells von Moulding, Dale A., Giles, Richard V., Spiller, David G., White, Michael R. H., Tidd, David M., Edwards, Steven W.

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The effects of 6-mercaptopurine nucleotide derivatives on the growth and survival of 6-mercaptopurine-sensitive and -resistant cell culture lines von JOHNSTON, H. P, HAWLEY, P, WHITE, S. E, GIBSON, I, TIDD, D. M

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Identification of a Good C-MYC Antisense Oligodeoxynucleotide Target Site and the Inactivity at This Site of Novel NCH Triplet-Targeting Ribozymes von Giles, Richard V., Spiller, David G., Clark, Richard E., Tidd, David M.

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The influence of target protein half-life on the effectiveness of antisense oligonucleotide analog-mediated biologic responses von Spiller, D G, Giles, R V, Broughton, C M, Grzybowski, J, Ruddell, C J, Tidd, D M, Clark, R E

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