Improving the human hazard characterization of chemicals: a Tox21 update von Tice, Raymond R, Austin, Christopher P, Kavlock, Robert J, Bucher, John R

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Toxicity profiling of flame retardants in zebrafish embryos using a battery of assays for developmental toxicity, neurotoxicity, cardiotoxicity and hepatotoxicity toward human rele... von Alzualde, Ainhoa, Behl, Mamta, Sipes, Nisha S., Hsieh, Jui-Hua, Alday, Aintzane, Tice, Raymond R., Paules, Richard S., Muriana, Arantza, Quevedo, Celia

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The Tox21 robotic platform for the assessment of environmental chemicals – from vision to reality von Attene-Ramos, Matias S., Miller, Nicole, Huang, Ruili, Michael, Sam, Itkin, Misha, Kavlock, Robert J., Austin, Christopher P., Shinn, Paul, Simeonov, Anton, Tice, Raymond R., Xia, Menghang

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Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes von Pei, Ying, Peng, Jun, Behl, Mamta, Sipes, Nisha S, Shockley, Keith R, Rao, Mahendra S, Tice, Raymond R, Zeng, Xianmin

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Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity von Ryan, Kristen R., Sirenko, Oksana, Parham, Fred, Hsieh, Jui-Hua, Cromwell, Evan F., Tice, Raymond R., Behl, Mamta

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Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity von Behl, Mamta, Hsieh, Jui-Hua, Shafer, Timothy J, Mundy, William R, Rice, Julie R, Boyd, Windy A, Freedman, Jonathan H, Hunter, E. Sidney, Jarema, Kimberly A, Padilla, Stephanie, Tice, Raymond R

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Bisphenol A affects androgen receptor function via multiple mechanisms von Teng, Christina, Goodwin, Bonnie, Shockley, Keith, Xia, Menghang, Huang, Ruili, Norris, John, Merrick, B. Alex, Jetten, Anton M., Austin, Christopher P., Tice, Raymond R.

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Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment von Kavlock, Robert J, Austin, Christopher P, Tice, Raymond R

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Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway von Huang, Ruili, Sakamuru, Srilatha, Martin, Matt T., Reif, David M., Judson, Richard S., Houck, Keith A., Casey, Warren, Hsieh, Jui-Hua, Shockley, Keith R., Ceger, Patricia, Fostel, Jennifer, Witt, Kristine L., Tong, Weida, Rotroff, Daniel M., Zhao, Tongan, Shinn, Paul, Simeonov, Anton, Dix, David J., Austin, Christopher P., Kavlock, Robert J., Tice, Raymond R., Xia, Menghang

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Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors von Huang, Ruili, Xia, Menghang, Cho, Ming-Hsuang, Sakamuru, Srilatha, Shinn, Paul, Houck, Keith A., Dix, David J., Judson, Richard S., Witt, Kristine L., Kaylock, Robert J., Tice, Raymond R., Austin, Christopher P.

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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death von Fox, Jennifer T, Sakamuru, Srilatha, Huang, Ruili, Teneva, Nedelina, Simmons, Steven O, Xia, Menghang, Tice, Raymond R, Austin, Christopher P, Myung, Kyungjae

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Screening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here von Behl, Mamta, Ryan, Kristen, Hsieh, Jui-Hua, Parham, Frederick, Shapiro, Andrew J, Collins, Bradley J, Sipes, Nisha S, Birnbaum, Linda S, Bucher, John R, Foster, Paul M D, Walker, Nigel J, Paules, Richard S, Tice, Raymond R

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Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage von Hsieh, Jui-Hua, Huang, Ruili, Lin, Ja-An, Sedykh, Alexander, Zhao, Jinghua, Tice, Raymond R, Paules, Richard S, Xia, Menghang, Auerbach, Scott S

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A Data Analysis Pipeline Accounting for Artifacts in Tox21 Quantitative High-Throughput Screening Assays von Hsieh, Jui-Hua, Sedykh, Alexander, Huang, Ruili, Xia, Menghang, Tice, Raymond R.

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Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening von Xia, Menghang, Huang, Ruili, Witt, Kristine L., Southall, Noel, Fostel, Jennifer, Cho, Ming-Hsuang, Jadhav, Ajit, Smith, Cynthia S., Inglese, James, Portier, Christopher J., Tice, Raymond R., Austin, Christopher P.

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Fourth International Workgroup on Genotoxicity testing: Results of the in vivo Comet assay workgroup von Burlinson, Brian, Tice, Raymond R., Speit, Günter, Agurell, Eva, Brendler-Schwaab, Susanne Y., Collins, Andrew R., Escobar, Patricia, Honma, Masamitsu, Kumaravel, Tirukalikundram S., Nakajima, Madoka, Sasaki, Yu F., Thybaud, Veronique, Uno, Yoshifumi, Vasquez, Marie, Hartmann, Andreas

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RNA-Seq profiling reveals novel hepatic gene expression pattern in aflatoxin B1 treated rats von Merrick, B Alex, Phadke, Dhiral P, Auerbach, Scott S, Mav, Deepak, Stiegelmeyer, Suzy M, Shah, Ruchir R, Tice, Raymond R

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Cell-Based High-Throughput Screening for Aromatase Inhibitors in the Tox21 10K Library von Chen, Shiuan, Hsieh, Jui-Hua, Huang, Ruili, Sakamuru, Srilatha, Hsin, Li-Yu, Xia, Menghang, Shockley, Keith R, Auerbach, Scott, Kanaya, Noriko, Lu, Hannah, Svoboda, Daniel, Witt, Kristine L, Merrick, B Alex, Teng, Christina T, Tice, Raymond R

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JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study result... von Uno, Yoshifumi, Kojima, Hajime, Omori, Takashi, Corvi, Raffaella, Honma, Masamistu, Schechtman, Leonard M., Tice, Raymond R., Beevers, Carol, Boeck, Marlies De, Burlinson, Brian, Hobbs, Cheryl A., Kitamoto, Sachiko, Kraynak, Andrew R., McNamee, James, Nakagawa, Yuzuki, Pant, Kamala, Plappert-Helbig, Ulla, Priestley, Catherine, Takasawa, Hironao, Wada, Kunio, Wirnitzer, Uta, Asano, Norihide, Escobar, Patricia A., Lovell, David, Morita, Takeshi, Nakajima, Madoka, Ohno, Yasuo, Hayashi, Makoto

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Systematic Study of Mitochondrial Toxicity of Environmental Chemicals Using Quantitative High Throughput Screening von Attene-Ramos, Matias S, Huang, Ruili, Sakamuru, Srilatha, Witt, Kristine L, Beeson, Gyda C, Shou, Louie, Schnellmann, Rick G, Beeson, Craig C, Tice, Raymond R, Austin, Christopher P, Xia, Menghang

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