Therapeutic approaches to Alzheimer’s disease von Thorsett, Eugene D, Latimer, Lee H

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Design, Synthesis, and Crystal Structure of Hydroxyethyl Secondary Amine-Based Peptidomimetic Inhibitors of Human β-Secretase von Maillard, Michel C, Hom, Roy K, Benson, Timothy E, Moon, Joseph B, Mamo, Shumeye, Bienkowski, Michael, Tomasselli, Alfredo G, Woods, Danielle D, Prince, D. Bryan, Paddock, Donna J, Emmons, Thomas L, Tucker, John A, Dappen, Michael S, Brogley, Louis, Thorsett, Eugene D, Jewett, Nancy, Sinha, Sukanto, John, Varghese

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Design and Synthesis of Hydroxyethylene-Based Peptidomimetic Inhibitors of Human β-Secretase von Hom, Roy K, Gailunas, Andrea F, Mamo, Shumeye, Fang, Larry Y, Tung, Jay S, Walker, Donald E, Davis, David, Thorsett, Eugene D, Jewett, Nancy E, Moon, Joseph B, John, Varghese

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Design of Substrate-Based Inhibitors of Human β-Secretase von Tung, Jay S, Davis, David L, Anderson, John P, Walker, Don E, Mamo, Shumeye, Jewett, Nancy, Hom, Roy K, Sinha, Sukanto, Thorsett, Eugene D, John, Varghese

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Design and Synthesis of Statine-Based Cell-Permeable Peptidomimetic Inhibitors of Human β-Secretase von Hom, Roy K, Fang, Larry Y, Mamo, Shumeye, Tung, Jay S, Guinn, Ashley C, Walker, Don E, Davis, David L, Gailunas, Andrea F, Thorsett, Eugene D, Sinha, Sukanto, Knops, Jeroen E, Jewett, Nancy E, Anderson, John P, John, Varghese

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Discovery of a potent, orally bioavailable pyrimidine VLA-4 antagonist effective in a sheep asthma model von Semko, Christopher M., Chen, Linda, Dressen, Darren B., Dreyer, Mark L., Dunn, Whitney, Farouz, Francine S., Freedman, Stephen B., Holsztynska, Elizabeth J., Jefferies, Michael, Konradi, Andrei W., Liao, Anna, Lugar, Judevin, Mutter, Linda, Pleiss, Michael A., Quinn, Kevin P., Thompson, Thomas, Thorsett, Eugene D., Vandevert, Christopher, Xu, Ying-Zi, Yednock, Ted A.

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A series of C-Terminal amino alcohol dipeptide Aβ inhibitors von Garofalo, Albert W., Wone, David W.G., Phuc, Angela, Audia, James E., Bales, Cheryl A., Dovey, Harry F., Dressen, Darren B., Folmer, Beverly, Goldbach, Erich G., Guinn, Ashley C., Latimer, Lee H., Mabry, Thomas E., Nissen, Jeffrey S., Pleiss, Michael A., Sohn, Stephen, Thorsett, Eugene D., Tung, Jay S., Wu, Jing

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From Peptide to Non-Peptide. 1. The Elucidation of a Bioactive Conformation of the Arginine-Glycine-Aspartic Acid Recognition Sequence von McDowell, Robert S, Gadek, Thomas R, Barker, Peter L, Burdick, Daniel J, Chan, Kathyrn S, Quan, Clifford L, Skelton, Nicholas, Struble, Martin, Thorsett, Eugene D

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Mild conversion of carboxamides and carboxylic acid hydrazides to acids and esters von Greenlee, William J, Thorsett, Eugene D

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From Peptide to Non-Peptide. 2. The de Novo Design of Potent, Non-peptidal Inhibitors of Platelet Aggregation Based on a Benzodiazepinedione Scaffold von McDowell, Robert S, Blackburn, Brent K, Gadek, Thomas R, McGee, Lawrence R, Rawson, Thomas, Reynolds, Mark E, Robarge, Kirk D, Somers, Todd C, Thorsett, Eugene D

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Conformationally restricted inhibitors of angiotensin-converting enzyme. Synthesis and computations von Thorsett, Eugene D, Harris, Elbert E, Aster, Susan D, Peterson, Elwood R, Snyder, James P, Springer, James P, Hirshfield, Jordan, Tristram, Edward W, Patchett, Arthur A

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Synthesis of 2-aryl-cis-3a,6a-octahydropyrrolo[2,3-b]pyrroles von Thorsett, Eugene D, Harris, Elbert E, Patchett, Arthur A

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LACTAM COMPOUND von THORSETT, EUGENE, D

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Phosphorus-Containing Inhibitors of Angiotensin-Converting Enzyme von Thorsett, Eugene D., Harris, Elbert E., Peterson, Elwood R., Greenlee, William J., Patchett, Arthur A., Ulm, Edgar H., Vassil, Theodore C.

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Lactam compound to inhibit beta-amyloid peptide release or synthesis von THORSETT EUGENE D, AUDIA JAMES EDMUND, LATIMER LEE H, MCDANIEL STACEY LEIGH, NISSEN JEFFREY SCOTT, JOHN VARGHESE, TUNG JAY S

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LACTAM COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND USE OF IT FOR PRODUCING PHARMACEUTICAL COMPOSITION von MCDANIEL, STACEY LEIGH, JOHN, VARGHESE, LATIMER, LEE H, NISSEN, JEFFREY SCOTT, TUNG, JAY S, AUDIA, JAMES EDMUND, THORSETT, EUGENE D

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LACTAM COMPOUND von THORSETT EUGENE D, AUDIA JAMES EDMUND, LATIMER LEE H, MCDANIEL STACEY LEIGH, NISSEN JEFFREY SCOTT, JOHN VARGHESE, TUNG JAY S

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HETEROCYCLIC COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY .ALPHA.4 INTEGRINS von KONRADI, ANDREI W, PLEISS, MICHAEL A, STAPPENBECK, FRANK, STUPI, BRIAN P, XU, YING-ZI, SEMKO, CHRISTOPHER M, SMITH, JENIFER, THORSETT, EUGENE D

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LACTAM COMPOUND von MCDANIEL, STACEY LEIGH, JOHN, VARGHESE, LATIMER, LEE H, NISSEN, JEFFREY SCOTT, TUNG, JAY S, AUDIA, JAMES EDMUND, THORSETT, EUGENE D

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Compounds Useful for Inhibiting Chk1 von THORSETT EUGENE D, GAUDINO JOHN JOSEPH, HOLCOMB RYAN COATSWORTH, FAROUZ FRANCINE S

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