Increased protein damage in renal glomeruli, retina, nerve, plasma and urine and its prevention by thiamine and benfotiamine therapy in a rat model of diabetes von Karachalias, N, Babaei-Jadidi, R, Rabbani, N, Thornalley, P. J

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Degradation products of proteins damaged by glycation, oxidation and nitration in clinical type 1 diabetes von AHMED, N, BABAEI-JADIDI, R, HOWELL, S. K, BEISSWENGER, P. J, THORNALLEY, P. J

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High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease von Thornalley, P. J, Babaei-Jadidi, R, Al Ali, H, Rabbani, N, Antonysunil, A, Larkin, J, Ahmed, A, Rayman, G, Bodmer, C. W

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High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study von Rabbani, N, Alam, S. S, Riaz, S, Larkin, J. R, Akhtar, M. W, Shafi, T, Thornalley, P. J

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Accumulation of free adduct glycation, oxidation, and nitration products follows acute loss of renal function von Rabbani, N., Sebekova, K., Sebekova, K., Heidland, A., Thornalley, P.J.

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Arginine-directed glycation and decreased HDL plasma concentration and functionality von Godfrey, L, Yamada-Fowler, N, Smith, J, Thornalley, P J, Rabbani, N

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High-dose thiamine therapy counters dyslipidaemia in streptozotocin-induced diabetic rats von BABAEI-JADIDI, R, KARACHALIAS, N, KUPICH, C, AHMED, N, THORNALLEY, P. J

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Advanced glycation endproducts: what is their relevance to diabetic complications von Ahmed, N, Thornalley, P.J

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Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo von Murphy, Michael P., Bayir, Hülya, Belousov, Vsevolod, Chang, Christopher J., Davies, Kelvin J. A., Davies, Michael J., Dick, Tobias P., Finkel, Toren, Forman, Henry J., Janssen-Heininger, Yvonne, Gems, David, Kagan, Valerian E., Kalyanaraman, Balaraman, Larsson, Nils-Göran, Milne, Ginger L., Nyström, Thomas, Poulsen, Henrik E., Radi, Rafael, Van Remmen, Holly, Schumacker, Paul T., Thornalley, Paul J., Toyokuni, Shinya, Winterbourn, Christine C., Yin, Huiyong, Halliwell, Barry

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Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolec... von Shinohara, M, Thornalley, P J, Giardino, I, Beisswenger, P, Thorpe, S R, Onorato, J, Brownlee, M

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Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes von Kilhovd, B.K., Giardino, I., Torjesen, P.A., Birkeland, K.I., Berg, T.J., Thornalley, P.J, Brownlee, M., Hanssen, K.F.

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The glyoxalase system : new developments towards functional characterization of a metabolic pathway fundamental to biological life von THORNALLEY, P. J

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Signal transduction activated by the cancer chemopreventive isothiocyanates: cleavage of BID protein, tyrosine phosphorylation and activation of JNK von Xu, K, Thornalley, P J

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Kinetics and mechanism of the reaction of aminoguanidine with the α-oxoaldehydes glyoxal, methylglyoxal, and 3-deoxyglucosone under physiological conditions von Thornalley, Paul J, Yurek-George, Alexander, Argirov, Ongian K

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Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy von Rabbani, N., Thornalley, P. J.

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Suppression of the Accumulation of Triosephosphates and Increased Formation of Methylglyoxal in Human Red Blood Cells during Hyperglycaemia by Thiamine In Vitro von Thornalley, Paul J., Jahan, Ismat, Ng, Rita

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Accumulation of α-oxoaldehydes during oxidative stress: a role in cytotoxicity von Abordo, Evelyn A, Minhas, Harjit S, Thornalley, Paul J

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Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro von Xu, Ke, Thornalley, Paul J.

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Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alp... von Lo, T W, Westwood, M E, McLellan, A C, Selwood, T, Thornalley, P J

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Advanced Glycation End Product Free Adducts Are Cleared by Dialysis von AGALOU, S, AHMED, N, THORNALLEY, P J, DAWNAY, A

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