Sensing of HSV-1 by the cGAS–STING pathway in microglia orchestrates antiviral defence in the CNS von Reinert, Line S., Lopušná, Katarína, Winther, Henriette, Sun, Chenglong, Thomsen, Martin K., Nandakumar, Ramya, Mogensen, Trine H., Meyer, Morten, Vægter, Christian, Nyengaard, Jens R., Fitzgerald, Katherine A., Paludan, Søren R.

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The cGAS-STING pathway is a therapeutic target in a preclinical model of hepatocellular carcinoma von Thomsen, Martin K., Skouboe, Morten K., Boularan, Cedric, Vernejoul, Fabienne, Lioux, Thierry, Leknes, Siv L., Berthelsen, Martin F., Riedel, Maria, Cai, Huiqiang, Joseph, Justin V., Perouzel, Eric, Tiraby, Michele, Vendelbo, Mikkel H., Paludan, Søren R.

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Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection von Thomsen, Martin K., Nandakumar, Ramya, Stadler, Daniela, Malo, Antje, Valls, Roser Marin, Wang, Fan, Reinert, Line S., Dagnæs‐Hansen, Frederik, Hollensen, Anne Kruse, Mikkelsen, Jacob Giehm, Protzer, Ulrike, Paludan, Søren R.

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Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses von Holm, Christian K., Rahbek, Stine H., Gad, Hans Henrik, Bak, Rasmus O., Jakobsen, Martin R., Jiang, Zhaozaho, Hansen, Anne Louise, Jensen, Simon K., Sun, Chenglong, Thomsen, Martin K., Laustsen, Anders, Nielsen, Camilla G., Severinsen, Kasper, Xiong, Yingluo, Burdette, Dara L., Hornung, Veit, Lebbink, Robert Jan, Duch, Mogens, Fitzgerald, Katherine A., Bahrami, Shervin, Mikkelsen, Jakob Giehm, Hartmann, Rune, Paludan, Søren R.

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Engineered lentivirus-derived nanoparticles (LVNPs) for delivery of CRISPR/Cas ribonucleoprotein complexes supporting base editing, prime editing and in vivo gene modification von Haldrup, Jakob, Andersen, Sofie, Labial, Alexander Rafael LaVilla, Wolff, Jonas Holst, Frandsen, Frederik Plum, Skov, Thomas Wisbech, Rovsing, Anne Bruun, Nielsen, Ian, Jakobsen, Thomas Stax, Askou, Anne Louise, Thomsen, Martin K, Corydon, Thomas J, Thomsen, Emil Aagaard, Mikkelsen, Jacob Giehm

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STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice von Skouboe, Morten K, Knudsen, Alice, Reinert, Line S, Boularan, Cedric, Lioux, Thierry, Perouzel, Eric, Thomsen, Martin K, Paludan, Søren R

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Regulation of Steatohepatitis and PPARγ Signaling by Distinct AP-1 Dimers von Hasenfuss, Sebastian C., Bakiri, Latifa, Thomsen, Martin K., Williams, Evan G., Auwerx, Johan, Wagner, Erwin F.

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CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression von Cai, Huiqiang, Zhang, Bin, Ahrenfeldt, Johanne, Joseph, Justin V., Riedel, Maria, Gao, Zongliang, Thomsen, Sofie K., Christensen, Ditte S., Bak, Rasmus O., Hager, Henrik, Vendelbo, Mikkel H., Gao, Xin, Birkbak, Nicolai, Thomsen, Martin K.

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Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation von Bakiri, Latifa, Hamacher, Rainer, Graña, Osvaldo, Guío-Carrión, Ana, Campos-Olivas, Ramón, Martinez, Lola, Dienes, Hans P, Thomsen, Martin K, Hasenfuss, Sebastian C, Wagner, Erwin F

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Dominant-negative SERPING1 variants cause intracellular retention of C1 inhibitor in hereditary angioedema von Haslund, Didde, Ryø, Laura Barrett, Seidelin Majidi, Sara, Rose, Iben, Skipper, Kristian Alsbjerg, Fryland, Tue, Bohn, Anja Bille, Koch, Claus, Thomsen, Martin K, Palarasah, Yaseelan, Corydon, Thomas J, Bygum, Anette, Nejsum, Lene N, Mikkelsen, Jacob Giehm

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β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma von Francis, Jeffrey C, Thomsen, Martin K, Taketo, Makoto M, Swain, Amanda

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The double-edge sword of CRISPR application for in vivo studies von Thomsen, Martin K.

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Activator protein 1 transcription factor fos‐related antigen 1 (fra‐1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism von Hasenfuss, Sebastian C., Bakiri, Latifa, Thomsen, Martin K., Hamacher, Rainer, Wagner, Erwin F.

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Pre-Clinical Models to Study Human Prostate Cancer von Thomsen, Martin K., Busk, Morten

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Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis von Francis, Jeffrey C, McCarthy, Afshan, Thomsen, Martin K, Ashworth, Alan, Swain, Amanda

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Application of CRISPR for In Vivo Mouse Cancer Studies von Thomsen, Martin K.

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A truncated reverse transcriptase enhances prime editing by split AAV vectors von Gao, Zongliang, Ravendran, Sujan, Mikkelsen, Nanna S., Haldrup, Jakob, Cai, Huiqiang, Ding, Xiangning, Paludan, Søren R., Thomsen, Martin K., Mikkelsen, Jacob Giehm, Bak, Rasmus O.

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Liver cancer development driven by the AP-1/c-Jun~Fra-2 dimer through c-Myc von Bakiri, Latifa, Hasenfuss, Sebastian C, Guío-Carrión, Ana, Thomsen, Martin K, Hasselblatt, Peter, Wagner, Erwin F

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STEEP mediates STING ER exit and activation of signaling von Zhang, Bao-cun, Nandakumar, Ramya, Reinert, Line S., Huang, Jinrong, Laustsen, Anders, Gao, Zong-liang, Sun, Cheng-long, Jensen, Søren Beck, Troldborg, Anne, Assil, Sonia, Berthelsen, Martin F., Scavenius, Carsten, Zhang, Yan, Windross, Samuel J., Olagnier, David, Prabakaran, Thaneas, Bodda, Chiranjeevi, Narita, Ryo, Cai, Yujia, Zhang, Cong-gang, Stenmark, Harald, Doucet, Christine M., Noda, Takeshi, Guo, Zheng, Goldbach-Mansky, Raphaela, Hartmann, Rune, Chen, Zhijian J., Enghild, Jan J., Bak, Rasmus O., Thomsen, Martin K., Paludan, Søren R.

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Treatment Represents a Key Driver of Metastatic Cancer Evolution von Christensen, Ditte S., Ahrenfeldt, Johanne, Sokač, Mateo, Kisistók, Judit, Thomsen, Martin K., Maretty, Lasse, McGranahan, Nicholas, Birkbak, Nicolai J.

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