Structure−Activity Relationships of Polymyxin Antibiotics von Velkov, Tony, Thompson, Philip E, Nation, Roger L, Li, Jian

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The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism von Wootten, Denise, Reynolds, Christopher A., Smith, Kevin J., Mobarec, Juan C., Koole, Cassandra, Savage, Emilia E., Pabreja, Kavita, Simms, John, Sridhar, Rohan, Furness, Sebastian G.B., Liu, Mengjie, Thompson, Philip E., Miller, Laurence J., Christopoulos, Arthur, Sexton, Patrick M.

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A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens von Roberts, Kade D., Zhu, Yan, Azad, Mohammad A. K., Han, Mei-Ling, Wang, Jiping, Wang, Lynn, Yu, Heidi H., Horne, Andrew S., Pinson, Jo-Anne, Rudd, David, Voelcker, Nicolas H., Patil, Nitin A., Zhao, Jinxin, Jiang, Xukai, Lu, Jing, Chen, Ke, Lomovskaya, Olga, Hecker, Scott J., Thompson, Philip E., Nation, Roger L., Dudley, Michael N., Griffith, David C., Velkov, Tony, Li, Jian

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IRAP Inhibitors: M1-Aminopeptidase Family Inspiration von Barlow, Nicholas, Thompson, Philip E.

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Aqueous extracts of Urtica dioica (stinging nettle) leaf contain a P2-purinoceptor antagonist-Implications for male fertility von Eise, Nicole T, Simpson, Jamie S, Thompson, Philip E, Ventura, Sabatino

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A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity von Deris, Zakuan Z, Akter, Jesmin, Sivanesan, Sivashangarie, Roberts, Kade D, Thompson, Philip E, Nation, Roger L, Li, Jian, Velkov, Tony

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Structural Determinants of Isoform Selectivity in PI3K Inhibitors von Miller, Michelle S, Thompson, Philip E, Gabelli, Sandra B

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The Phytosulfokine (PSK) Receptor Is Capable of Guanylate Cyclase Activity and Enabling Cyclic GMP-dependent Signaling in Plants von Kwezi, Lusisizwe, Ruzvidzo, Oziniel, Wheeler, Janet I., Govender, Kershini, Iacuone, Sylvana, Thompson, Philip E., Gehring, Chris, Irving, Helen R.

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Parallel and antiparallel cyclic d/l peptide nanotubes von Silk, Mitchell R, Newman, Janet, Ratcliffe, Julian C, White, Jacinta F, Caradoc-Davies, Tom, Price, Jason R, Perrier, Sébastien, Thompson, Philip E, Chalmers, David K

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A novel chemical biology and computational approach to expedite the discovery of new-generation polymyxins against life-threatening Acinetobacter baumannii von Jiang, Xukai, Patil, Nitin A., Azad, Mohammad A. K., Wickremasinghe, Hasini, Yu, Heidi, Zhao, Jinxin, Zhang, Xinru, Li, Mengyao, Gong, Bin, Wan, Lin, Ma, Wendong, Thompson, Philip E., Yang, Kai, Yuan, Bing, Schreiber, Falk, Wang, Lushan, Velkov, Tony, Roberts, Kade D., Li, Jian

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Defeating MYC with drug combinations or dual-targeting drugs von Thompson, Philip E., Shortt, Jake

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Antimicrobial Activity and Toxicity of the Major Lipopeptide Components of Polymyxin B and Colistin: Last-Line Antibiotics against Multidrug-Resistant Gram-Negative Bacteria von Roberts, Kade D, Azad, Mohammad A. K, Wang, Jiping, Horne, Andrew S, Thompson, Philip E, Nation, Roger L, Velkov, Tony, Li, Jian

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Characterization of the Polymyxin D Synthetase Biosynthetic Cluster and Product Profile of Paenibacillus polymyxa ATCC 10401 von Galea, Charles A, Han, Meiling, Zhu, Yan, Roberts, Kade, Wang, Jiping, Thompson, Philip E, L, Jian, Velkov, Tony

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Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines von Morrison, Rick, Al-Rawi, Jasim M.A., Jennings, Ian G., Thompson, Philip E., Angove, Michael J.

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Expanding the Library of Covalent Cysteine Cathepsin Probes Featuring Sulfoxonium Ylide Electrophiles von Xu, Bangyan, Mountford, Simon J., Thompson, Philip E., Edgington-Mitchell, Laura E.

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major human and mouse granzymes are structurally and functionally divergent von Kaiserman, Dion, Bird, Catherina H, Sun, Jiuru, Matthews, Antony, Ung, Kheng, Whisstock, James C, Thompson, Philip E, Trapani, Joseph A, Bird, Phillip I

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An extensional strain sensing mechanosome drives adhesion-independent platelet activation at supraphysiological hemodynamic gradients von Zainal Abidin, Nurul A, Poon, Eric K W, Szydzik, Crispin, Timofeeva, Mariia, Akbaridoust, Farzan, Brazilek, Rose J, Tovar Lopez, Francisco J, Ma, Xiao, Lav, Chitrarth, Marusic, Ivan, Thompson, Philip E, Mitchell, Arnan, Ooi, Andrew S H, Hamilton, Justin R, Nesbitt, Warwick S

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Design and Evaluation of Novel Polymyxin Fluorescent Probes von Yun, Bo, Roberts, Kade D, Thompson, Philip E, Nation, Roger L, Velkov, Tony, Li, Jian

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The Next Generation of Phosphodiesterase Inhibitors:  Structural Clues to Ligand and Substrate Selectivity of Phosphodiesterases von Manallack, David T, Hughes, Richard A, Thompson, Philip E

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TNP Analogues Inhibit the Virulence Promoting IP3-4 Kinase Arg1 in the Fungal Pathogen Cryptococcus neoformans von Desmarini, Desmarini, Truong, Daniel, Wilkinson-White, Lorna, Desphande, Chandrika, Torrado, Mario, Mackay, Joel P., Matthews, Jacqueline M., Sorrell, Tania C., Lev, Sophie, Thompson, Philip E., Djordjevic, Julianne Teresa

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