Selective and genetic constraints on pneumococcal serotype switching von Croucher, Nicholas J, Kagedan, Lisa, Thompson, Claudette M, Parkhill, Julian, Bentley, Stephen D, Finkelstein, Jonathan A, Lipsitch, Marc, Hanage, William P

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A modified Janus cassette (Sweet Janus) to improve allelic replacement efficiency by high-stringency negative selection in Streptococcus pneumoniae von Li, Yuan, Thompson, Claudette M, Lipsitch, Marc

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Interleukin-17A mediates acquired immunity to pneumococcal colonization von Lu, Ying-Jie, Gross, Jane, Bogaert, Debby, Finn, Adam, Bagrade, Linda, Zhang, Qibo, Kolls, Jay K, Srivastava, Amit, Lundgren, Anna, Forte, Sophie, Thompson, Claudette M, Harney, Kathleen F, Anderson, Porter W, Lipsitch, Marc, Malley, Richard

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Surface Charge of Streptococcus pneumoniae Predicts Serotype Distribution von Li, Yuan, Weinberger, Daniel M, Thompson, Claudette M, Trzciński, Krzysztof, Lipsitch, Marc

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CD4+T Cells Mediate Antibody-Independent Acquired Immunity to Pneumococcal Colonization von Malley, Richard, Trzcinski, Krzysztof, Srivastava, Amit, Thompson, Claudette M., Anderson, Porter W., Lipsitch, Marc, Bloom, Barry R.

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A MAPS Vaccine Induces Multipronged Systemic and Tissue-Resident Cellular Responses and Protects Mice against Mycobacterium tuberculosis von O'Hara, Joanne M, Wakabayashi, Shoko, Siddiqi, Noman, Cheung, Elaine, Babunovic, Gregory H, Thompson, Claudette M, Lu, Ying-Jie, Rubin, Eric J, Malley, Richard, Zhang, Fan

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The impact of serotype-specific vaccination on phylodynamic parameters of Streptococcus pneumoniae and the pneumococcal pan-genome von Azarian, Taj, Grant, Lindsay R, Arnold, Brian J, Hammitt, Laura L, Reid, Raymond, Santosham, Mathuram, Weatherholtz, Robert, Goklish, Novalene, Thompson, Claudette M, Bentley, Stephen D, O'Brien, Katherine L, Hanage, William P, Lipsitch, Marc

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Within-Host Selection Is Limited by an Effective Population of Streptococcus pneumoniae during Nasopharyngeal Colonization von Li, Yuan, Thompson, Claudette M, Trzciński, Krzysztof, Lipsitch, Marc

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Interference between Streptococcus pneumoniae and Staphylococcus aureus: In Vitro Hydrogen Peroxide-Mediated Killing by Streptococcus pneumoniae von REGEV-YOCHAY, Gili, TRZCINSKI, Krzysztof, THOMPSON, Claudette M, MALLEY, Richard, LIPSITCH, Marc

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Recognition of Pneumolysin by Toll-like Receptor 4 Confers Resistance to Pneumococcal Infection von Malley, Richard, Henneke, Philipp, Morse, Sarah C., Cieslewicz, Michael J., Lipsitch, Marc, Thompson, Claudette M., Kurt-Jones, Evelyn, Paton, James C., Wessels, Michael R., Golenbock, Douglas T.

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Effect of Serotype on Pneumococcal Competition in a Mouse Colonization Model von Trzciński, Krzysztof, Li, Yuan, Weinberger, Daniel M, Thompson, Claudette M, Cordy, Derrick, Bessolo, Andrew, Malley, Richard, Lipsitch, Marc

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Distinct effects on diversifying selection by two mechanisms of immunity against Streptococcus pneumoniae von Li, Yuan, Gierahn, Todd, Thompson, Claudette M, Trzciński, Krzysztof, Ford, Christopher B, Croucher, Nicholas, Gouveia, Paulo, Flechtner, Jessica B, Malley, Richard, Lipsitch, Marc

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Antibody-Independent, Interleukin-17A-Mediated, Cross-Serotype Immunity to Pneumococci in Mice Immunized Intranasally with the Cell Wall Polysaccharide von Malley, Richard, Srivastava, Amit, Lipsitch, Marc, Thompson, Claudette M, Watkins, Claire, Tzianabos, Arthur, Anderson, Porter W

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Induction of Broad Immunity against Invasive Salmonella Disease by a Quadrivalent Combination Salmonella MAPS Vaccine Targeting Salmonella Enterica Serovars Typhimurium, Enteritidi... von Boerth, Emily M, Gong, Joyce, Roffler, Becky, Thompson, Claudette M, Song, Boni, Malley, Sasha F, Hirsch, Angelika, MacLennan, Calman A, Zhang, Fan, Malley, Richard, Lu, Ying-Jie

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Protection against Nasopharyngeal Colonization by Streptococcus pneumoniae Is Mediated by Antigen-Specific CD4⁺ T Cells von Trzciński, Krzysztof, Thompson, Claudette M, Srivastava, Amit, Basset, Alan, Malley, Richard, Lipsitch, Marc

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SpxB Is a Suicide Gene of Streptococcus pneumoniae and Confers a Selective Advantage in an In Vivo Competitive Colonization Model von REGEV-YOCHAY, Gili, TRZCINSKI, Krzysztof, THOMPSON, Claudette M, LIPSITCH, Marc, MALLEY, Richard

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Protection against Pneumococcal Colonization and Fatal Pneumonia by a Trivalent Conjugate of a Fusion Protein with the Cell Wall Polysaccharide von Lu, Ying-Jie, Forte, Sophie, Thompson, Claudette M, Anderson, Porter W, Malley, Richard

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Antibody-Independent, CD4⁺ T-Cell-Dependent Protection against Pneumococcal Colonization Elicited by Intranasal Immunization with Purified Pneumococcal Proteins von Basset, Alan, Thompson, Claudette M, Hollingshead, Susan K, Briles, David E, Ades, Edwin W, Lipsitch, Marc, Malley, Richard

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Options for Inactivation, Adjuvant, and Route of Topical Administration of a Killed, Unencapsulated Pneumococcal Whole-Cell Vaccine von Lu, Ying-Jie, Yadav, Puja, Clements, John D, Forte, Sophie, Srivastava, Amit, Thompson, Claudette M, Seid, Robert, Look, Jee, Alderson, Mark, Tate, Andrea, Maisonneuve, Jean-François, Robertson, George, Anderson, Porter W, Malley, Richard

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Strain Characteristics of Streptococcus pneumoniae Carriage and Invasive Disease Isolates during a Cluster-Randomized Clinical Trial of the 7-Valent Pneumococcal Conjugate Vaccine von Lipsitch, Marc, O'Neill, Keith, Cordy, Derrick, Bugalter, Boris, Trzcinski, Krzysztof, Thompson, Claudette M., Goldstein, Richard, Pelton, Stephen, Huot, Heather, Bouchet, Valerie, Reid, Raymond, Santosham, Mathuram, O'Brien, Katherine L.

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