Ligand-induced changes in hepatitis C virus NS5B polymerase structure von Rigat, Karen, Wang, Yi, Hudyma, Thomas W., Ding, Min, Zheng, Xiaofan, Gentles, Robert G., Beno, Brett R., Gao, Min, Roberts, Susan B.

Volltext

Syntheses and initial evaluation of a series of indolo-fused heterocyclic inhibitors of the polymerase enzyme (NS5B) of the hepatitis C virus von Zheng, Xiaofan, Hudyma, Thomas W., Martin, Scott W., Bergstrom, Carl, Ding, Min, He, Feng, Romine, Jeffrey, Poss, Michael A., Kadow, John F., Chang, Chong-Hwan, Wan, John, Witmer, Mark R., Morin, Paul, Camac, Daniel M., Sheriff, Steven, Beno, Brett R., Rigat, Karen L., Wang, Ying-Kai, Fridell, Robert, Lemm, Julie, Qiu, Dike, Liu, Mengping, Voss, Stacey, Pelosi, Lenore, Roberts, Susan B., Gao, Min, Knipe, Jay, Gentles, Robert G.

Volltext

Synthesis and SAR studies of novel heteroaryl fused tetracyclic indole-diamide compounds: Potent allosteric inhibitors of the hepatitis C virus NS5B polymerase von Ding, Min, He, Feng, Hudyma, Thomas W., Zheng, Xiaofan, Poss, Michael A., Kadow, John F., Beno, Brett R., Rigat, Karen L., Wang, Ying-Kai, Fridell, Robert A., Lemm, Julie A., Qiu, Dike, Liu, Mengping, Voss, Stacey, Pelosi, Lenore A., Roberts, Susan B., Gao, Min, Knipe, Jay, Gentles, Robert G.

Volltext

Phosphonooxymethyl prodrugs of the broad spectrum antifungal azole, ravuconazole: Synthesis and biological properties von UEDA, Yasutsugu, MATISKELLA, John D, VARIA, Sailesh, KNIPE, Jay, MING ZHENG, MATHEW, Marina, MOSURE, Kathy, CLARK, Junius, LAMB, Lucinda, MEDIN, Ivette, QI GAO, HUANG, Stella, GOLIK, Jerzy, CHEN, Chung-Pin, BRONSON, Joanne J, CONNOLLY, Timothy P, HUDYMA, Thomas W, VENKATESH, Srini, DALI, Mandar, KANG, Shin-Hong, BARBOUR, Nancy, TEJWANI, Ravi

Volltext

Novel semi-synthetic nocathiacin antibiotics: synthesis and antibacterial activity of bis- and mono- O-alkylated derivatives von Regueiro-Ren, Alicia, Naidu, B.Narasimhulu, Zheng, Xiaofan, Hudyma, Thomas W., Connolly, Timothy P., Matiskella, John D., Zhang, Yunhui, Kim, Oak K., Sorenson, Margaret E., Pucci, Michael, Clark, Junius, Bronson, Joanne J., Ueda, Yasutsugu

Volltext

A practical and efficient synthesis of 6-carboalkoxy-13-cycloalkyl-5H-indolo[2,1-a][2]benzazepine-10-carboxylic acid derivatives von Hewawasam, Piyasena, Tu, Yong, Hudyma, Thomas W., Zhang, Xiaofan, Gentles, Robert G., Kadow, John F., Meanwell, Nicholas A.

Volltext

ChemInform Abstract: A Practical and Efficient Synthesis of 6-Carboalkoxy-13-cycloalkyl-5H-indolo[2,1-a] [2]benzazepine-10-carboxylic Acid Derivatives von Hewawasam, Piyasena, Tu, Yong, Hudyma, Thomas W., Zhang, Xiaofan, Gentles, Robert G., Kadow, John F., Meanwell, Nicholas A.

Volltext

Trypsin Digestion of Hepatitis C Virus NS5B Polymerase Exposes a Hinge at the Active Site von Rigat, Karen, Wang, Yi, Hudyma, Thomas W., Ding, Min, Zheng, Xiaofan, Gentles, Robert G., Beno, Brett R., Gao, Min, Roberts, Susan B.

Volltext

Antiallergy agents. 2. 2-Phenyl-5-(1H-tetrazol-5-yl)pyrimidin-4(3H)-ones von Juby, Peter F, Hudyma, Thomas W, Brown, Myron, Essery, John M, Partyka, Richard A

Volltext

Antiallergy agents. 1. 1,6-Dihydro-6-oxo-2-phenylpyrimidine-5-carboxylic acids and esters von Juby, Peter F, Hudyma, Thomas W, Brown, Myron, Essery, John M, Partyka, Richard A

Volltext

Synthesis and anti-MRSA Activity of Novel Cephalosporin Derivatives von D'Andrea, Stan V., Bonner, Daniel, Bronson, Joanne J., Clark, Junius, Denbleyker, Ken, Fung-Tomc, Joan, Hoeft, Shelley E., Hudyma, Thomas W., Matiskella, John D., Miller, Raymond F., Misco, Peter F., Pucci, Michael, Sterzycki, Roman, Tsai, Yuan, Ueda, Yasutsuga, Wichtowski, John A., Singh, Janak, Kissick, Thomas P., North, Jeffery T., Pullockaran, Annie, Humora, Michael, Boyhan, Brenda, Vu, Truc, Fritz, Alan, Heikes, J., Fox, Rita, Godfrey, Jollie D., Perrone, Robert, Kaplan, Murray, Kronenthal, David, Mueller, Richard H.

Volltext

Synthesis and structure-activity relationship of C-3 quaternary ammonium cephalosporins exhibiting anti-MRSA activities von Kim, Oak K., Hudyma, Thomas W., Matiskella, John D., Ueda, Yasutsugu, Bronson, Joanne J., Mansuri, Muzammil M.

Volltext

Synthesis and release of doxorubicin from a cephalosporin based prodrug by a β-lactamase-immunoconjugate von Hudyma, Thomas W., Bush, Karen, Colson, Kimberly L., Firestone, Raymond A., King, H.Dalton

Volltext

HCV NS5B inhibitors von MARTIN, SCOTT W, BERGSTROM, CARL P, HUDYMA, THOMAS W

Volltext bestellen

HCV NS5B INHIBITORS von MARTIN, SCOTT W, BERGSTROM, CARL P, HUDYMA, THOMAS W

Volltext bestellen

HCV NS5B INHIBITORS von BERGSTROM CARL P, MARTIN SCOTT W, HUDYMA THOMAS W

Volltext bestellen

HCV NS5B-hæmmere von BERGSTROM, CARL, P, MARTIN, SCOTT, W, HUDYMA, THOMAS, W

Volltext bestellen

HCV NS5B INHIBITORS von CARL P. BERGSTROM, SCOTT W. MARTIN, THOMAS W. HUDYMA

Volltext bestellen

HCV NS5B INHIBITORS von CARL P. BERGSTROM, SCOTT W. MARTIN, THOMAS W. HUDYMA

Volltext bestellen

HCV NS5B INHIBITORS von BERGSTROM, CARL, P, MARTIN, SCOTT, W, HUDYMA, THOMAS, W

Volltext bestellen