Anti‐KIT antibody, barzolvolimab, reduces skin mast cells and disease activity in chronic inducible urticaria von Terhorst‐Molawi, Dorothea, Hawro, Tomasz, Grekowitz, Eva, Kiefer, Lea, Merchant, Kunal, Alvarado, Diego, Thomas, Lawrence J., Hawthorne, Thomas, Crowley, Elizabeth, Heath‐Chiozzi, Margo, Metz, Martin, Maurer, Marcus

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Anti‐KIT monoclonal antibody CDX‐0159 induces profound and durable mast cell suppression in a healthy volunteer study von Alvarado, Diego, Maurer, Marcus, Gedrich, Richard, Seibel, Scott B., Murphy, Michael B., Crew, Linda, Goldstein, Joel, Crocker, Andrea, Vitale, Laura A., Morani, Pamela A., Thomas, Lawrence J., Hawthorne, Thomas R., Keler, Tibor, Young, Diane, Crowley, Elizabeth, Kankam, Martin, Heath‐Chiozzi, Margo

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M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1 von Rajaram, Murugesan V.S., Arnett, Eusondia, Azad, Abul K., Guirado, Evelyn, Ni, Bin, Gerberick, Abigail D., He, Li-Zhen, Keler, Tibor, Thomas, Lawrence J., Lafuse, William P., Schlesinger, Larry S.

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CDX-301: a novel medical countermeasure for hematopoietic acute radiation syndrome in mice von Satyamitra, Merriline, Cary, Lynnette, Dunn, Dylan, Holmes-Hampton, Gregory P., Thomas, Lawrence J., Ghosh, Sanchita P.

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Development of a Novel Antibody-Drug Conjugate for the Potential Treatment of Ovarian, Lung, and Renal Cell Carcinoma Expressing TIM-1 von Thomas, Lawrence J, Vitale, Laura, O'Neill, Thomas, Dolnick, Ree Y, Wallace, Paul K, Minderman, Hans, Gergel, Lauren E, Forsberg, Eric M, Boyer, James M, Storey, James R, Pilsmaker, Catherine D, Hammond, Russell A, Widger, Jenifer, Sundarapandiyan, Karuna, Crocker, Andrea, Marsh, Jr, Henry C, Keler, Tibor

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CDX-301 prevents radiation-induced dysregulation of miRNA expression and biogenesis von Soni, Dharmendra Kumar, Kumar, Vidya P., Biswas, Shukla, Holmes-Hampton, Gregory P., Bhattacharyya, Sharmistha, Thomas, Lawrence J., Biswas, Roopa, Ghosh, Sanchita P.

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The expression level of lysophosphatidylcholine acyltransferase 1 (LPCAT1) correlates to the progression of prostate cancer von Zhou, Xinchun, Lawrence, Thomas J., He, Zhi, Pound, Charles R., Mao, Jinghe, Bigler, Steven A.

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CDX-585, a Bispecific Antibody with Dual Targeting of ILT4 and PD-1 Checkpoint Pathways von Murphy, Michael B., Vitale, Laura, Xia, Shukai, Peng, Zeyu, O’Neill, Thomas, Lillquist, Jay, Wasiuk, Anna, Weidlick, Jeff, Widger, Jenifer, Mills-Chen, Laura, Crocker, Andrea, Patterson, Colleen, Boyer, James, Baronas, April R., Chen, Mingjiu, Davis, Hugh M., Ma, Mark, Goldstein, Joel, Thomas, Lawrence J., Alvarado, Diego, Marsh, Henry C., Keler, Tibor

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PD-1 Blockade and CD27 Stimulation Activate Distinct Transcriptional Programs That Synergize for CD8 + T-Cell-Driven Antitumor Immunity von Buchan, Sarah L, Fallatah, Mohannad, Thirdborough, Stephen M, Taraban, Vadim Y, Rogel, Anne, Thomas, Lawrence J, Penfold, Christine A, He, Li-Zhen, Curran, Michael A, Keler, Tibor, Al-Shamkhani, Aymen

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Vaccine-Induced Antibodies Inhibit CETP Activity In Vivo and Reduce Aortic Lesions in a Rabbit Model of Atherosclerosis von Rittershaus, Charles W, Miller, David P, Thomas, Lawrence J, Picard, Michele D, Honan, Christopher M, Emmett, Constance D, Pettey, Carolyn L, Adari, Hedy, Hammond, Russell A, Beattie, David T, Callow, Allan D, Marsh, Henry C, Ryan, Una S

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Development of CDX-1140, an agonist CD40 antibody for cancer immunotherapy von Vitale, Laura A., Thomas, Lawrence J., He, Li-Zhen, O’Neill, Thomas, Widger, Jenifer, Crocker, Andrea, Sundarapandiyan, Karuna, Storey, James R., Forsberg, Eric M., Weidlick, Jeffrey, Baronas, April R., Gergel, Lauren E., Boyer, James M., Sisson, Crystal, Goldstein, Joel, Marsh, Henry C., Keler, Tibor

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Development of CDX-527: a bispecific antibody combining PD-1 blockade and CD27 costimulation for cancer immunotherapy von Vitale, Laura A., He, Li-Zhen, Thomas, Lawrence J., Wasiuk, Anna, O’Neill, Thomas, Widger, Jenifer, Crocker, Andrea, Mills-Chen, Laura, Forsberg, Eric, Weidlick, Jeffrey, Patterson, Colleen, Hammond, Russell A., Boyer, James, Sisson, Crystal, Alvarado, Diego, Goldstein, Joel, Marsh, Henry C., Keler, Tibor

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Good Health and Wellness: Measuring Impact Through an Indigenous Lens von Lawrence, Thomas J, James, Rosalina D

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CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy von Wasiuk, Anna, Testa, James, Weidlick, Jeff, Sisson, Crystal, Vitale, Laura, Widger, Jenifer, Crocker, Andrea, Thomas, Lawrence J, Goldstein, Joel, Marsh, Henry C, Keler, Tibor, He, Li-Zhen

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Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment von Turaj, Anna H., Hussain, Khiyam, Cox, Kerry L., Rose-Zerilli, Matthew J.J., Testa, James, Dahal, Lekh N., Chan, H.T. Claude, James, Sonya, Field, Vikki L., Carter, Matthew J., Kim, Hyung J., West, Jonathan J., Thomas, Lawrence J., He, Li-Zhen, Keler, Tibor, Johnson, Peter W.M., Al-Shamkhani, Aymen, Thirdborough, Stephen M., Beers, Stephen A., Cragg, Mark S., Glennie, Martin J., Lim, Sean H.

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Agonist anti-human CD27 monoclonal antibody induces T cell activation and tumor immunity in human CD27-transgenic mice von He, Li-Zhen, Prostak, Naseem, Thomas, Lawrence J, Vitale, Laura, Weidlick, Jeffrey, Crocker, Andrea, Pilsmaker, Catherine D, Round, Sarah M, Tutt, Alison, Glennie, Martin J, Marsh, Henry, Keler, Tibor

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Soluble CR1 Therapy Improves Complement Regulation in C3 Glomerulopathy von YUZHOU ZHANG, NESTER, Carla M, HOLANDA, Danniele G, MARSH, Henry C, HAMMOND, Russell A, THOMAS, Lawrence J, MEYER, Nicole C, HUNSICKER, Lawrence G, SETHI, Sanjeev, SMITH, Richard J. H

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Practical Considerations in Determining Adversity and the No-Observed-Adverse-Effect-Level (NOAEL) in Nonclinical Safety Studies: Challenges, Perspectives and Case Studies von Kale, Vijay P., Bebenek, Ilona, Ghantous, Hanan, Kapeghian, John, Singh, Bhanu P., Thomas, Lawrence J.

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Development of a Human Monoclonal Antibody for Potential Therapy of CD27-Expressing Lymphoma and Leukemia von VITALE, Laura A, HE, Li-Zhen, ANSELL, Stephen M, MARSH, Henry, KELER, Tibor, THOMAS, Lawrence J, WIDGET, Jennifer, WEIDLICK, Jeffrey, CROCKER, Andrea, O'NEILL, Thomas, STOREY, James, GLENNIE, Martin J, GROTE, Deanna M

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Targeting human CD27 with an agonist antibody stimulates T-cell activation and antitumor immunity von Thomas, Lawrence J, He, Li-Zhen, Marsh, Henry, Keler, Tibor

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