Isolation, Structure Elucidation, and Biomimetic Total Synthesis of Versicolamide B, and the Isolation of Antipodal (-)-Stephacidin A and (+)-Notoamide B from Aspergillus versicolo... von Greshock, Thomas J, Grubbs, Alan W, Jiao, Ping, Wicklow, Donald T, Gloer, James B, Williams, Robert M

Volltext

Synthesis of Complex Druglike Molecules by the Use of Highly Functionalized Bench-Stable Organozinc Reagents von Greshock, Thomas J., Moore, Keith P., McClain, Ray T., Bellomo, Ana, Chung, Cheol K., Dreher, Spencer D., Kutchukian, Peter S., Peng, Zhengwei, Davies, Ian W., Vachal, Petr, Ellwart, Mario, Manolikakes, Sophia M., Knochel, Paul, Nantermet, Philippe G.

Volltext

Isolation of Antipodal (−)-Versicolamide B and Notoamides L−N from a Marine-Derived Aspergillus sp von Tsukamoto, Sachiko, Kawabata, Tetsuro, Kato, Hikaru, Greshock, Thomas J, Hirota, Hiroshi, Ohta, Tomihisa, Williams, Robert M

Volltext

A Concise, Biomimetic Total Synthesis of Stephacidin A and Notoamide B von Greshock, Thomas J., Grubbs, Alan W., Tsukamoto, Sachiko, Williams, Robert M.

Volltext

Genome-Based Characterization of Two Prenylation Steps in the Assembly of the Stephacidin and Notoamide Anticancer Agents in a Marine-Derived Aspergillus sp von Ding, Yousong, Wet, Jeffrey R. de, Cavalcoli, James, Li, Shengying, Greshock, Thomas J, Miller, Kenneth A, Finefield, Jennifer M, Sunderhaus, James D, McAfoos, Timothy J, Tsukamoto, Sachiko, Williams, Robert M, Sherman, David H

Volltext

Synthesis and Conformation−Activity Relationships of the Peptide Isosteres of FK228 and Largazole von Bowers, Albert A, Greshock, Thomas J, West, Nathan, Estiu, Guillermina, Schreiber, Stuart L, Wiest, Olaf, Williams, Robert M, Bradner, James E

Volltext

Improved Biomimetic Total Synthesis of d,l -Stephacidin A von Greshock, Thomas J, Williams, Robert M

Volltext

Isolation of Notoamide E, a Key Precursor in the Biosynthesis of Prenylated Indole Alkaloids in a Marine-Derived Fungus, Aspergillus sp von Tsukamoto, Sachiko, Kato, Hikaru, Greshock, Thomas J, Hirota, Hiroshi, Ohta, Tomihisa, Williams, Robert M

Volltext

MK-7622: A First-in-Class M1 Positive Allosteric Modulator Development Candidate von Beshore, Douglas C., N. Di Marco, Christina, Chang, Ronald K., Greshock, Thomas J., Ma, Lei, Wittmann, Marion, Seager, Matthew A., Koeplinger, Kenneth A., Thompson, Charles D., Fuerst, Joy, Hartman, George D., Bilodeau, Mark T., Ray, William J., Kuduk, Scott D.

Volltext

Ultra-fast microscale purification of chiral racemates and achiral pharmaceuticals with analytical supercritical fluid chromatography von Hayes, Michael, Hettiarachchi, Kanaka, Lang, Simon, Wang, Jun, Greshock, Thomas J.

Volltext

Improved Total Synthesis of the Potent HDAC Inhibitor FK228 (FR-901228) von Greshock, Thomas J, Johns, Deidre M, Noguchi, Yasuo, Williams, Robert M

Volltext

Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve von Klein, Rebecca M., Layton, Mark E., Regan, Hillary, Regan, Christopher P., Li, Yuxing, Filzen, Tracey, Cato, Matt, Clements, Michelle K., Wang, Jixin, Sanoja, Raul, Greshock, Thomas J., Roecker, Anthony J., Pero, Joseph E., Kim, Ron, Burgey, Christopher, John, Christopher T., Wang, Ying-Hong, Bhandari, Neetesh, Struyk, Arie, Kraus, Richard L., Henze, Darrell A., Houghton, Andrea K.

Volltext

Synthetic studies on palau’amine. Construction of the cyclopentane core via an asymmetric 1,3-dipolar cycloaddition von Namba, Kosuke, Inai, Makoto, Sundermeier, Uta, Greshock, Thomas J., Williams, Robert M.

Volltext

Concise, biomimetic total synthesis of d,l-marcfortine C von Greshock, Thomas J., Grubbs, Alan W., Williams, Robert M.

Volltext

Biomimetic Total Synthesis of Malbrancheamide and Malbrancheamide B von Miller, Kenneth A., Welch, Timothy R., Greshock, Thomas J., Ding, Yousong, Sherman, David H., Williams, Robert M.

Volltext

Microscale Purification with Direct Charged Aerosol Detector Quantitation Using Selective Online One- or Two-Dimensional Liquid Chromatography von Hettiarachchi, Kanaka, Streckfuss, Eric, Sanzone, Jillian R., Wang, Jun, Hayes, Michael, Kong, May, Greshock, Thomas J.

Volltext

Premalbrancheamide: Synthesis, Isotopic Labeling, Biosynthetic Incorporation, and Detection in Cultures of Malbranchea aurantiaca von Ding, Yousong, Greshock, Thomas J, Miller, Kenneth A, Sherman, David H, Williams, Robert M

Volltext

Subminute micro-isolation of pharmaceuticals with ultra-high pressure liquid chromatography von Hettiarachchi, Kanaka, Hayes, Michael, Desai, Aditya J., Wang, Jun, Ren, Zhao, Greshock, Thomas J.

Volltext

Correction to Isolation of Notoamide E, a Key Precursor in the Biosynthesis of Prenylated Indole Alkaloids in a Marine-Derived Fungus, Aspergillus sp von Tsukamoto, Sachiko, Kato, Hikaru, Greshock, Thomas J, Hirota, Hiroshi, Ohta, Tomihisa, Williams, Robert M

Volltext

Predictions of Chromatography Methods by Chemical Structure Similarity to Accelerate High-Throughput Medicinal Chemistry von Wang, Jun, Yen, Rose, Beck, Armen G., Aggarwal, Pankaj, Kong, May, Hayes, Michael, Jabri, Salman, Greshock, Thomas J., Hettiarachchi, Kanaka

Volltext