A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes von Locke, F, Agarwal, R, Kunnavakkam, R, van Besien, K, Larson, R A, Odenike, O, Godley, L A, Liu, H, Le Beau, M M, Gurbuxani, S, Thirman, M J, Sipkins, D, White, C, Artz, A, Stock, W

Volltext

Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia : Correlation with scaffold att... von BROEKER, P. L. S, SUPER, H. G, THIRMAN, M. J, POMYKALA, H, YONEBAYASHI, Y, TANABE, S, ZELEZNIK-LE, N, ROWLEY, J. D

Volltext

Rearrangement of the MLL Gene in Acute Lymphoblastic and Acute Myeloid Leukemias with 11q23 Chromosomal Translocations von Thirman, Michael J, Gill, Heidi J, Burnett, Robert C, Mbangkollo, David, McCabe, Norah R, Kobayashi, Hirofumi, Ziemin-van der Poel, Sheryl, Kaneko, Yasuhiko, Morgan, Rodman, Sandberg, Avery A, Chaganti, R.S.K, Larson, Richard A, Le Beau, Michelle M, Diaz, Manuel O, Rowley, Janet D

Volltext

Regulation of MEIS1 by distal enhancer elements in acute leukemia von Wang, Q-f, Li, Y-j, Dong, J-f, Li, B, Kaberlein, J J, Zhang, L, Arimura, F E, Luo, R T, Ni, J, He, F, Wu, J, Mattison, R, Zhou, J, Wang, C-z, Prabhakar, S, Nobrega, M A, Thirman, M J

Volltext

The Elongation Domain of ELL Is Dispensable but Its ELL-Associated Factor 1 Interaction Domain Is Essential for MLL-ELL-Induced Leukemogenesis von Luo, Roger T., Lavau, Catherine, Du, Changchun, Simone, Federico, Polak, Paul E., Kawamata, Shin, Thirman, Michael J.

Volltext

Cloning of ELL, a Gene that Fuses to MLL in a t(11;19)(q23;p13.1) in Acute Myeloid Leukemia von Thirman, Michael J., Levitan, Denise A., Kobayashi, Hiro, Simon, M. Celeste, Rowley, Janet D.

Volltext

Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia von DiNardo, Courtney D, Jonas, Brian A, Pullarkat, Vinod, Thirman, Michael J, Garcia, Jacqueline S, Wei, Andrew H, Konopleva, Marina, Döhner, Hartmut, Letai, Anthony, Fenaux, Pierre, Koller, Elizabeth, Havelange, Violaine, Leber, Brian, Esteve, Jordi, Wang, Jianxiang, Pejsa, Vlatko, Hájek, Roman, Porkka, Kimmo, Illés, Árpád, Lavie, David, Lemoli, Roberto M, Yamamoto, Kazuhito, Yoon, Sung-Soo, Jang, Jun-Ho, Yeh, Su-Peng, Turgut, Mehmet, Hong, Wan-Jen, Zhou, Ying, Potluri, Jalaja, Pratz, Keith W

Volltext

Rearrangements of the MLL Gene in Therapy-Related Acute Myeloid Leukemia in Patients Previously Treated With Agents Targeting DNA-Topoisomerase II von Gill Super, Heidi J., McCabe, Norah R., Thirman, Michael J., Larson, Richard A., Le Beau, Michelle M., Pedersen-Bjergaard, Jens, Philip, Preben, Diaz, Manuel O., Rowley, Janet D.

Volltext

Unexplained anemia predominates despite an intensive evaluation in a racially diverse cohort of older adults from a referral anemia clinic von Artz, Andrew S, Thirman, Michael J

Volltext

Retrovirus-Mediated Gene Transfer of MLL-ELL Transforms Primary Myeloid Progenitors and Causes Acute Myeloid Leukemias in Mice von Lavau, Catherine, Luo, Roger T., Du, Changchun, Thirman, Michael J.

Volltext

Cloning of cDNAs of the MLL Gene that Detect DNA Rearrangements and Altered RNA Transcripts in Human Leukemic Cells with 11q23 Translocations von McCabe, Norah R., Burnett, Robert C., Gill, Heidi J., Thirman, Michael J., Mbangkollo, David, Kipiniak, Magdalena, van Melle, Elizabeth, Sheryl Ziemin-van Der Poel, Rowley, Janet D., Diaz, Manuel O.

Volltext

Induction of cytochrome CYPIA1 and formation of toxic metabolites of benzo[a]pyrene by rat aorta: a possible role in atherogenesis von Thirman, M J, Albrecht, J H, Krueger, M A, Erickson, R R, Cherwitz, D L, Park, S S, Gelboin, H V, Holtzman, J L

Volltext

Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (RESONATE-17): a phase 2, open-label, multicentre study von O'Brien, Susan, Prof, Jones, Jeffrey A, MD, Coutre, Steven E, Prof, Mato, Anthony R, MD, Hillmen, Peter, Prof, Tam, Constantine, MD, Österborg, Anders, Prof, Siddiqi, Tanya, MD, Thirman, Michael J, MD, Furman, Richard R, MD, Ilhan, Osman, Prof, Keating, Michael J, Prof, Call, Timothy G, MD, Brown, Jennifer R, MD, Stevens-Brogan, Michelle, MSc, Li, Yunfeng, PhD, Clow, Fong, ScD, James, Danelle F, MD, Chu, Alvina D, MD, Hallek, Michael, Prof, Stilgenbauer, Stephan, Prof

Volltext

EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein von Simone, Federico, Polak, Paul E., Kaberlein, Joseph J., Luo, Roger T., Levitan, Denise A., Thirman, Michael J.

Volltext

Abnormalities of chromosome band 11q23 and the MLL gene in pediatric myelomonocytic and monoblastic leukemias : identification of the t(9;11) as an indicator of long survival von MARTINEZ-CLIMENT, J. A, ESPINOSA, R. III, THIRMAN, M. J, LE BEAU, M. M, ROWLEY, J. D

Volltext

Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes von Byun, Jung S, Wong, Madeline M, Cui, Wenwu, Idelman, Gila, Li, Quentin, De Siervi, Adriana, Bilke, Sven, Haggerty, Cynthia M, Player, Audrey, Wang, Yong Hong, Thirman, Michael J, Kaberlein, Joseph J, Petrovas, Constantinos, Koup, Richard A, Longo, Dan, Ozato, Keiko, Gardner, Kevin

Volltext

Molecular analysis of the T-cell acute lymphoblastic leukemia-associated t(1;7)(p34;q34) that fuses LCK and TCRB von BURNETT, R. C, THIRMAN, M. J, ROWLEY, J. D, DIAZ, M. O

Volltext

Neurotoxicity of meperidine von Goetting, Mark G, Thirman, Michael J

Volltext

Heterogeneity of breakpoints of 11q23 rearrangements in hematologic malignancies identified with fluorescence in situ hybridization von Kobayashi, Hirofumi, Espinosa, Rafael, Thirman, Michael J., Gill, Heidi J., Fernald, Anthony A., Diaz, Manuel O., Le Beau, Michelle M., Rowley, Janet D.

Volltext

The Elongation Factor ELL (Eleven-Nineteen Lysine-Rich Leukemia) Is a Selective Coregulator for Steroid Receptor Functions von Pascual-Le Tallec, Laurent, Simone, Federico, Viengchareun, Say, Meduri, Geri, Thirman, Michael J, Lombès, Marc

Volltext