Alteration of the Antitumor Immune Response by Cancer-Associated Fibroblasts von Ziani, Linda, Chouaib, Salem, Thiery, Jerome

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Modulation of the antitumor immune response by cancer-associated fibroblasts: mechanisms and targeting strategies to hamper their immunosuppressive functions von Thiery, Jerome

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Hypoxia increases melanoma-associated fibroblasts immunosuppressive potential and inhibitory effect on T cell-mediated cytotoxicity von Ziani, Linda, Buart, Stéphanie, Chouaib, Salem, Thiery, Jerome

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Melanoma-associated fibroblasts decrease tumor cell susceptibility to NK cell-mediated killing through matrix-metalloproteinases secretion von Ziani, Linda, Safta-Saadoun, Thouraya Ben, Gourbeix, Johanne, Cavalcanti, Andrea, Robert, Caroline, Favre, Gilles, Chouaib, Salem, Thiery, Jerome

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The Effect of Hypoxia and Hypoxia-Associated Pathways in the Regulation of Antitumor Response: Friends or Foes? von Abou Khouzam, Raefa, Zaarour, Rania Faouzi, Brodaczewska, Klaudia, Azakir, Bilal, Venkatesh, Goutham Hassan, Thiery, Jerome, Terry, Stéphane, Chouaib, Salem

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Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes von Walch, Michael, Dotiwala, Farokh, Mulik, Sachin, Thiery, Jerome, Kirchhausen, Tomas, Clayberger, Carol, Krensky, Alan M, Martinvalet, Denis, Lieberman, Judy

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Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling von Lal, Ashish, Thomas, Marshall P, Altschuler, Gabriel, Navarro, Francisco, O'Day, Elizabeth, Li, Xiao Ling, Concepcion, Carla, Han, Yoon-Chi, Thiery, Jerome, Rajani, Danielle K, Deutsch, Aaron, Hofmann, Oliver, Ventura, Andrea, Hide, Winston, Lieberman, Judy

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ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy von Messai, Yosra, Noman, Muhammad Zaeem, Hasmim, Meriem, Janji, Bassam, Tittarelli, Andrés, Boutet, Marie, Baud, Véronique, Viry, Elodie, Billot, Katy, Nanbakhsh, Arash, Ben Safta, Thouraya, Richon, Catherine, Ferlicot, Sophie, Donnadieu, Emmanuel, Couve, Sophie, Gardie, Betty, Orlanducci, Florence, Albiges, Laurence, Thiery, Jerome, Olive, Daniel, Escudier, Bernard, Chouaib, Salem

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Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis von Thiery, Jerome, Keefe, Dennis, Saffarian, Saviz, Martinvalet, Denis, Walch, Michael, Boucrot, Emmanuel, Kirchhausen, Tomas, Lieberman, Judy

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Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity von Tuli, Amit, Thiery, Jerome, James, Ashley M, Michelet, Xavier, Sharma, Mahak, Garg, Salil, Sanborn, Keri B, Orange, Jordan S, Lieberman, Judy, Brenner, Michael B

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Hypoxia increases mutational load of breast cancer cells through frameshift mutations von Hassan Venkatesh, Goutham, Bravo, Pamela, Shaaban Moustafa Elsayed, Walid, Amirtharaj, Francis, Wojtas, Bartosz, Abou Khouzam, Raefa, Hussein Nawafleh, Husam, Mallya, Sandeep, Satyamoorthy, Kapaettu, Dessen, Philippe, Rosselli, Filippo, Thiery, Jerome, Chouaib, Salem

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The Most Common VHL Point Mutation R167Q in Hereditary VHL Disease Interferes with Cell Plasticity Regulation von Buart, Stéphanie, Terry, Stéphane, Diop, M'boyba Khadija, Dessen, Philippe, Couvé, Sophie, Abdou, Abdérémane, Adam, Julien, Thiery, Jérôme, Savagner, Pierre, Chouaib, Salem

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Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes von Walch, Michael, Dotiwala, Farokh, Mulik, Sachin, Thiery, Jerome, Kirchhausen, Tomas, Clayberger, Carol, Krensky, Alan M., Martinvalet, Denis, Lieberman, Judy

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Role of Hypoxia-Mediated Autophagy in Tumor Cell Death and Survival von Zaarour, Rania F, Azakir, Bilal, Hajam, Edries Y, Nawafleh, Husam, Zeinelabdin, Nagwa A, Engelsen, Agnete S T, Thiery, Jérome, Jamora, Colin, Chouaib, Salem

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Role of Hypoxic Stress in Regulating Tumor Immunogenicity, Resistance and Plasticity von Terry, Stéphane, Faouzi Zaarour, Rania, Hassan Venkatesh, Goutham, Francis, Amirtharaj, El-Sayed, Walid, Buart, Stéphanie, Bravo, Pamela, Thiery, Jérome, Chouaib, Salem

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Granzyme B-induced Cell Death Involves Induction of p53 Tumor Suppressor Gene and Its Activation in Tumor Target Cells von Meslin, Franck, Thiery, Jerome, Richon, Catherine, Jalil, Abdelali, Chouaib, Salem

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Perforin: A Key Pore-Forming Protein for Immune Control of Viruses and Cancer von Thiery, Jerome, Lieberman, Judy

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p53 Potentiation of Tumor Cell Susceptibility to CTL Involves Fas and Mitochondrial Pathways von Thiery, Jerome, Abouzahr, Soraya, Dorothee, Guillaume, Jalil, Abdelali, Richon, Catherine, Vergnon, Isabelle, Mami-Chouaib, Fathia, Chouaib, Salem

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Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells von Walch, Michael, Keefe, Dennis, Kirchhausen, Tomas, Thiery, Jerome, Goping, Ing Swie, Martinvalet, Denis, Boulant, Steeve, Lieberman, Judy, Bleackley, R Chris, Boucrot, Emmanuel

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The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy von Chollat-Namy, Marie, Ben Safta-Saadoun, Thouraya, Haferssas, Djazia, Meurice, Guillaume, Chouaib, Salem, Thiery, Jerome

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