Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA von Jdey, Wael, Thierry, Sylvain, Popova, Tatiana, Stern, Marc-Henri, Dutreix, Marie

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Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives von Corona, Angela, Di Leva, Francesco Saverio, Thierry, Sylvain, Pescatori, Luca, Cuzzucoli Crucitti, Giuliana, Subra, Frederic, Delelis, Olivier, Esposito, Francesca, Rigogliuso, Giuseppe, Costi, Roberta, Cosconati, Sandro, Novellino, Ettore, Di Santo, Roberto, Tramontano, Enzo

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Drug-Driven Synthetic Lethality: Bypassing Tumor Cell Genetics with a Combination of AsiDNA and PARP Inhibitors von Jdey, Wael, Thierry, Sylvain, Russo, Christophe, Devun, Flavien, Al Abo, Muthana, Noguiez-Hellin, Patricia, Sun, Jian-Sheng, Barillot, Emmanuel, Zinovyev, Andrei, Kuperstein, Inna, Pommier, Yves, Dutreix, Marie

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The DNA Repair Inhibitor Dbait Is Specific for Malignant Hematologic Cells in Blood von Thierry, Sylvain, Jdey, Wael, Alculumbre, Solana, Soumelis, Vassili, Noguiez-Hellin, Patricia, Dutreix, Marie

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AsiDNA Treatment Induces Cumulative Antitumor Efficacy with a Low Probability of Acquired Resistance von Jdey, Wael, Kozlak, Maria, Alekseev, Sergey, Thierry, Sylvain, Lascaux, Pauline, Girard, Pierre-Marie, Bono, Françoise, Dutreix, Marie

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Quantitative analysis of the time-course of viral DNA forms during the HIV-1 life cycle von Munir, Soundasse, Thierry, Sylvain, Subra, Frédéric, Deprez, Eric, Delelis, Olivier

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A Chemically Defined TLR3 Agonist with Anticancer Activity von Le Naour, Julie, Thierry, Sylvain, Scuderi, Sarah Adriana, Boucard-Jourdin, Mathilde, Liu, Peng, Bonnin, Marc, Pan, Yuhong, Perret, Clémence, Zhao, Liwei, Mao, Misha, Renoux, Chloé, Pérez-Lanzón, María, Martin, Baptiste, Kepp, Oliver, Kroemer, Guido, Werlé, Bettina

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Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration von Thierry, Sylvain, Munir, Soundasse, Thierry, Eloïse, Subra, Frédéric, Leh, Hervé, Zamborlini, Alessia, Saenz, Dyana, Levy, David N, Lesbats, Paul, Saïb, Ali, Parissi, Vincent, Poeschla, Eric, Deprez, Eric, Delelis, Olivier

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Preclinical Studies Comparing Efficacy and Toxicity of DNA Repair Inhibitors, Olaparib, and AsiDNA, in the Treatment of Carboplatin-Resistant Tumors von Herath, Nirmitha I., Berthault, Nathalie, Thierry, Sylvain, Jdey, Wael, Lienafa, Marie-Christine, Bono, Françoise, Noguiez-Hellin, Patricia, Sun, Jian-Sheng, Dutreix, Marie

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TL-532, a novel specific Toll-like receptor 3 agonist rationally designed for targeting cancers: discovery process and biological characterization von Thierry, Sylvain, Maadadi, Sarah, Berton, Aurore, Dimier, Laura, Perret, Clémence, Vey, Nelly, Ourfali, Saïd, Saccas, Mathilde, Caron, Solène, Boucard-Jourdin, Mathilde, Colombel, Marc, Werle, Bettina, Bonnin, Marc

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Impact of Y143 HIV-1 Integrase Mutations on Resistance to Raltegravir In Vitro and In Vivo von DELELIS, Olivier, THIERRY, Sylvain, TCHERTANOV, Luba, MOUSCADET, Jean-François, SUBRA, Frédéric, SIMON, Françoise, MALET, Isabelle, ALLOUI, Chakib, SAYON, Sophie, CALVEZ, Vincent, DEPREZ, Eric, MARCELIN, Anne-Geneviève

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Impact of the Ku complex on HIV-1 expression and latency von Manic, Gwenola, Maurin-Marlin, Aurélie, Laurent, Fanny, Vitale, Ilio, Thierry, Sylvain, Delelis, Olivier, Dessen, Philippe, Vincendeau, Michelle, Leib-Mösch, Christine, Hazan, Uriel, Mouscadet, Jean-François, Bury-Moné, Stéphanie

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Comparison Between Several Integrase-defective Lentiviral Vectors Reveals Increased Integration of an HIV Vector Bearing a D167H Mutant von Qamar Saeed, Muhammad, Dufour, Noelle, Bartholmae, Cynthia, Sieranska, Urzula, Knopf, Malaika, Thierry, Eloïse, Thierry, Sylvain, Delelis, Olivier, Grandchamp, Nicolas, Pilet, Héloïse, Ravassard, Philippe, Massonneau, Julie, Pflumio, Françoise, von Kalle, Christof, Lachapelle, François, Bemelmans, Alexis-Pierre, Schmidt, Manfred, Serguera, Ché

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Cell Cycle Arrest in G2 Induces Human Immunodeficiency Virus Type 1 Transcriptional Activation through Histone Acetylation and Recruitment of CBP, NF-κB, and c-Jun to the Long Term... von THIERRY, Sylvain, MARECHAL, Vincent, ROSENZWAJG, Michelle, SABBAH, Michèle, REDEUILH, Gérard, NICOLAS, Jean-Claude, GOZLAN, Joël

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Abstract 1110: AsiDNA induce tumor sensitivity to PARP inhibitors in homologous recombination proficient breast cancer AsiDNA induce tumor sensitivity to PARP inhibitors in homolog... von DUTREIX, marie, Jdey, Wael, Thierry, sylvain, Kuperstein, Inna, Dixon, Graham

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Two-long terminal repeat (LTR) DNA circles are a substrate for HIV-1 integrase von Richetta, Clémence, Thierry, Sylvain, Thierry, Eloise, Lesbats, Paul, Lapaillerie, Delphine, Munir, Soundasse, Subra, Frédéric, Leh, Hervé, Deprez, Eric, Parissi, Vincent, Delelis, Olivier

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AsiDNA Treatment Induces Cumulative Antitumor Efficacy with a Low Probability of Acquired Resistance von Jdey, Wael, Kozlak, Maria, Alekseev, Sergey, Thierry, Sylvain, Lascaux, Pauline, Girard, Pierre-Marie, Bono, Françoise, Dutreix, Marie

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A Chemically Defined TLR3 Agonist with Anticancer Activity von Le Naour, Julie, Thierry, Sylvain, Scuderi, Sarah Adriana, Boucard-Jourdin, Mathilde, Liu, Peng, Bonnin, Marc, Pan, Yuhong, Perret, Clémence, Zhao, Liwei, Mao, Misha, Renoux, Chloé, Pérez-Lanzón, María, Martin, Baptiste, Kepp, Oliver, Kroemer, Guido, Werlé, Bettina

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Opposite transcriptional regulation of integrated vs unintegrated HIV genomes by the NF-κB pathway von Thierry, Sylvain, Thierry, Eloïse, Subra, Frédéric, Deprez, Eric, Leh, Hervé, Bury-Moné, Stéphanie, Delelis, Olivier

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Abstract 2085: The specific TLR3-agonist TL-532 induces life-long anti-tumor autovaccination, cross-immunity against unrelated cancers and reverses resistance to immune checkpoint... von Bonnin, Marc, Ourfali, Saïd, Boucard-Jourdin, Mathilde, Perret, Clémence, Renoux, Chloé, Vey, Nelly, Colombel, Marc, Werlé, Bettina, Thierry, Sylvain

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