Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo von Theys, J, Pennington, O, Dubois, L, Anlezark, G, Vaughan, T, Mengesha, A, Landuyt, W, Anné, J, Burke, P J, Dûrre, P, Wouters, B G, Minton, N P, Lambin, P

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OC-0237: Adding Notch inhibition increases efficacy of standard of care treatment in glioblastoma von Yahyanejad, S, King, H, Iglesias, V, Granton, P, Barbeau, L, Van Hoof, S, Groot, A, Habets, R, Prickaerts, J, Chalmers, A, Theys, J, Short, S, Verhaegen, F, Vooijs, M

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Targeting NOTCH pathway in Glioblastoma von Yahyanejad, S, King, H, Iglesias, V.S, Granton, P.V, Barbeau, L. M.O, van Hoof, S.J, Groot, A.J, Habets, R, Prickaerts, J, Chalmers, A.J, Short, S.C, Verhaegen, F, Theys, J, Vooijs, M

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Hypoxia as a target for combined modality treatments von Wouters, B.G, Weppler, S.A, Koritzinsky, M, Landuyt, W, Nuyts, S, Theys, J, Chiu, R.K, Lambin, P

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214: NOTCH and radiotherapy: does it matter? von Vooijs, M, Sosa Iglesias, V, Habets, R, Theys, J

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Orthotopic tumor models for glioma and NSCLC von Theys, J, van Hoof, S, Sosa Iglesias, V, Schijns, L, Barbeau, L, Lieuwes, N, Dubois, L, Verhaegen, F, Vooijs, M

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EP-1351: Efficacy of combination treatments of a NOTCH inhibitor and chemoradiotherapy in an orthotopic glioma model von Yahyanejad, S, Granton, P.V, Van Hoof, S, Barbeau, L, Theys, J, Verhaegen, F, Vooijs, M

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OC-0236: DTP-006: a novel, orally bioavailable hypoxia-activated prodrug von Niemans, R, Yaromina, A, Theys, J, Ashoorzadeh, A, Anderson, R, Bull, M, Guise, C, Hsu, H.L, Abbattista, M, Mowday, A, Patterson, A.V, Smaill, J.B, Ackerley, D.F, Dubois, L, Lambin, P

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Radio-responsive recA promoter significantly increases TNFα production in recombinant clostridia after 2 Gy irradiation von NUYTS, S, VAN MELLAERT, L, THEYS, J, LANDUYT, W, BOSMANS, E, ANNE, J, LAMBIN, P

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SP-0014: Radiation sensitivity and EMT in cancer: Role of the tumor microenvironment von Theys, J, Habets, R, Jutten, B, Groot, A, Paesmans, K, Lambin, P, Rouschop, K, Vooijs, M

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PO-428 Radiotherapy, immunocytokines and immune checkpoint inhibitors: finding the optimal combination von Pimentel, V Olivo, Marcus, D, Van der Wiel, A, Biemans, R, Lieuwes, NG, Neri, D, Theys, J, Yaromina, A, Dubois, LJ, Lambin, P

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Stable Escherichia coli-Clostridium acetobutylicum Shuttle Vector for Secretion of Murine Tumor Necrosis Factor Alpha von Theys, J, Nuyts, S, Landuyt, W, Van Mellaert, L, Dillen, C, Böhringer, M, Dürre, P, Lambin, P, Anné, J

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SP-0136: Off target effects with hypoxia activated prodrugs: lessons learned from PR-104A von Mowday, A., Dubois, L., Smaill, J., Patterson, A., Lambin, P., Theys, J.

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PD-0833 Exploiting tumor DNA repair status with the novel hypoxia-activated DNA alkylating agent CP-506 von van der Wiel, A., Yaromina, A., Lieuwes, N., Biemans, R., Theys, J., Dubois, L., Lambin, P.

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Insertion or Deletion of the Cheo Box Modifies Radiation Inducibility of Clostridium Promoters von NUYTS, S, VAN MELLAERT, L, BARBE, S, LAMMERTYN, E, THEYS, J, LANDUYT, W, BOSMANS, E, LAMBIN, P, ANNE, J

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Clostridium spores for tumor-specific drug delivery von Nuyts, S, Van Mellaert, L, Theys, J, Landuyt, W, Lambin, P, Anné, J

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OC-0065 Overcoming radioresistance with the hypoxia-activated prodrug CP-506: a pre-clinical in vivo study von Yaromina, A., Koi, L., van der Wiel, A., Lieuwes, N.G., Theys, J., Dubois, L., Krause, M., Lambin, P.

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OC-0203: Eliminating tumour hypoxia to improve the impact of immunotherapy von Marcus, D., Van der Wiel, A., Biemans, R., Lieuwes, N., Heyerick, A., Smaill, J., Patterson, A., Theys, J., Yaromina, A., Lambin, P., Dubois, L.

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Efficacy of gene therapy-delivered cytosine deaminase is determined by enzymatic activity but not expression von Dubois, L, Dresselaers, T, Landuyt, W, Paesmans, K, Mengesha, A, Wouters, B G, Hecke, P Van, Theys, J, Lambin, P

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The Use of Radiation-Induced Bacterial Promoters in Anaerobic Conditions: A Means to Control Gene Expression in Clostridium-Mediated Therapy for Cancer von Nuyts, Sandra, Van Mellaert, Lieve, Theys, Jan, Landuyt, Willy, Lambin, Philippe, Anné, Jozef

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