Cysteine proteases as therapeutic targets:does selectivity matter? A systematic review of calpain and cathepsin inhibitors von Siklos, Marton, BenAissa, Manel, Thatcher, Gregory R J

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Pharmacological manipulation of cGMP and NO/cGMP in CNS drug discovery von Hollas, Michael A., Ben Aissa, Manel, Lee, Sue H., Gordon-Blake, Jesse M., Thatcher, Gregory R.J.

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Remembering your A, B, C's: Alzheimer's disease and ABCA1 von Lewandowski, Cutler T., Laham, Megan S., Thatcher, Gregory R.J.

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Potential Mechanisms of Estrogen Quinone Carcinogenesis von Bolton, Judy L, Thatcher, Gregory R. J

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Furoxans (1,2,5-Oxadiazole-N-Oxides) as Novel NO Mimetic Neuroprotective and Procognitive Agents von Schiefer, Isaac T, VandeVrede, Lawren, Fa’, Mauro, Arancio, Ottavio, Thatcher, Gregory R. J

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Systemic Candesartan Treatment Modulates Behavior, Synaptic Protein Levels, and Neuroinflammation in Female Mice That Express Human APOE4 von Scheinman, Sarah B, Zaldua, Steve, Dada, Adedoyin, Krochmaliuk, Kateryna, Dye, Katherine, Marottoli, Felecia M, Thatcher, Gregory R J, Tai, Leon M

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Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons von Yu, Lei, Tasaki, Shinya, Schneider, Julie A, Arfanakis, Konstantinos, Duong, Duc M, Wingo, Aliza P, Wingo, Thomas S, Kearns, Nicola, Thatcher, Gregory R. J, Seyfried, Nicholas T, Levey, Allan I, De Jager, Philip L, Bennett, David A

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Inhibition of Amyloidogenesis by Nonsteroidal Anti-inflammatory Drugs and Their Hybrid Nitrates von Schiefer, Isaac T, Abdul-Hay, Samer, Wang, Huali, Vanni, Michael, Qin, Zhihui, Thatcher, Gregory R. J

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Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments von Fata, Francesca, Silvestri, Ilaria, Ardini, Matteo, Ippoliti, Rodolfo, Di Leandro, Luana, Demitri, Nicola, Polentarutti, Maurizio, Di Matteo, Adele, Lyu, Haining, Thatcher, Gregory R.J, Petukhov, Pavel A, Williams, David L, Angelucci, Francesco

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Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity von Shen, Zhengnan, Ratia, Kiira, Cooper, Laura, Kong, Deyu, Lee, Hyun, Kwon, Youngjin, Li, Yangfeng, Alqarni, Saad, Huang, Fei, Dubrovskyi, Oleksii, Rong, Lijun, Thatcher, Gregory R J, Xiong, Rui

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TrkA expression directs the anti-neoplastic activity of MLK3 inhibitors in triple-negative breast cancer von Nair, Rakesh Sathish, Kumar, Sandeep, Das, Subhasis, Singh, Sunil Kumar, Srivastava, Piush, Sondarva, Gautam, Rao, Arundhati, Sinha, Subhash C., Xiong, Rui, Bloem, Laura, Hoskins, Kent, Thatcher, Gregory R. J., Rana, Basabi, Rana, Ajay

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Dimethyl Fumarate Inhibits the Nuclear Factor κB Pathway in Breast Cancer Cells by Covalent Modification of p65 Protein von Kastrati, Irida, Siklos, Marton I., Calderon-Gierszal, Esther L., El-Shennawy, Lamiaa, Georgieva, Gergana, Thayer, Emily N., Thatcher, Gregory R.J., Frasor, Jonna

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Channeling Nicotinamide Phosphoribosyltransferase (NAMPT) to Address Life and Death von Velma, Ganga Reddy, Krider, Isabella S., Alves, Erick T. M., Courey, Jenna M., Laham, Megan S., Thatcher, Gregory R. J.

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Novel Selective Estrogen Receptor Downregulators (SERDs) Developed against Treatment-Resistant Breast Cancer von Xiong, Rui, Zhao, Jiong, Gutgesell, Lauren M, Wang, Yueting, Lee, Sue, Karumudi, Bhargava, Zhao, Huiping, Lu, Yunlong, Tonetti, Debra A, Thatcher, Gregory R. J

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Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo von Petukhova, Valentina Z., Aboagye, Sammy Y., Ardini, Matteo, Lullo, Rachel P., Fata, Francesca, Byrne, Margaret E., Gabriele, Federica, Martin, Lucy M., Harding, Luke N. M., Gone, Vamshikrishna, Dangi, Bikash, Lantvit, Daniel D., Nikolic, Dejan, Ippoliti, Rodolfo, Effantin, Grégory, Ling, Wai Li, Johnson, Jeremy J., Thatcher, Gregory R. J., Angelucci, Francesco, Williams, David L., Petukhov, Pavel A.

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MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3 von Singh, Sunil Kumar, Kumar, Sandeep, Viswakarma, Navin, Principe, Daniel R., Das, Subhasis, Sondarva, Gautam, Nair, Rakesh Sathish, Srivastava, Piush, Sinha, Subhash C., Grippo, Paul J., Thatcher, Gregory R. J., Rana, Basabi, Rana, Ajay

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Structure-Guided Design and Synthesis of Pyridinone-Based Selective Bromodomain and Extra-Terminal Domain (BET)-First Bromodomain (BD1) Inhibitors von Li, Yangfeng, Shen, Zhengnan, Ratia, Kiira, Zhao, Jiong, Huang, Fei, Dubrovyskyii, Oleksii, Indukuri, Divakar, Fu, Jiqiang, Lozano Ramos, Omar, Thatcher, Gregory R. J., Xiong, Rui

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Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbocicl... von Li, Yangfeng, Zhao, Jiong, Gutgesell, Lauren M, Shen, Zhengnan, Ratia, Kiira, Dye, Katherine, Dubrovskyi, Oleksii, Zhao, Huiping, Huang, Fei, Tonetti, Debra A, Thatcher, Gregory R. J, Xiong, Rui

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Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer von Lu, Yunlong, Gutgesell, Lauren M, Xiong, Rui, Zhao, Jiong, Li, Yangfeng, Rosales, Carlo I, Hollas, Michael, Shen, Zhengnan, Gordon-Blake, Jesse, Dye, Katherine, Wang, Yueting, Lee, Sue, Chen, Hu, He, Donghong, Dubrovyskyii, Oleksii, Zhao, Huiping, Huang, Fei, Lasek, Amy W, Tonetti, Debra A, Thatcher, Gregory R. J

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Iodocyclization of S–(homo)propargyl dithiocarbamates: Regiospecific synthesis of 2-imino(iminium)-1, 3-dithiolanes/dithianes/dithiepanes von Soleymani, Farinaz, Ziyaei Halimehjani, Azim, Asar, Farzane Jafari, Thatcher, Gregory R.J.

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