Peptide-In-Groove Interactions Link Target Proteins to the β -Propeller of Clathrin von Haar, Ernst ter, Harrison, Stephen C., Kirchhausen, Tomas

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Structure of Mitogen-activated Protein Kinase-activated Protein (MAPKAP) Kinase 2 Suggests a Bifunctional Switch That Couples Kinase Activation with Nuclear Export von Meng, Wuyi, Swenson, Lora L., Fitzgibbon, Matthew J., Hayakawa, Koto, ter Haar, Ernst, Behrens, Anne E., Fulghum, John R., Lippke, Judith A.

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Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism von ter Haar, Ernst, Koth, Christopher M., Abdul-Manan, Norzehan, Swenson, Lora, Coll, Joyce T., Lippke, Judith A., Lepre, Christopher A., Garcia-Guzman, Miguel, Moore, Jonathan M.

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Crystal Structure of the P38α-MAPKAP Kinase 2 Heterodimer von Haar, Ernst ter, Prabakhar, Prakash, Liu, Xun, Lepre, Christopher

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3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3β von ARNOST, Michael, PIERCE, Al, TER HAAR, Ernst, LAUFFER, David, MADDEN, Jaren, TANNER, Kirk, GREEN, Jeremy

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Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK) von FARMER, Luc J, BEMIS, Guy, TER HAAR, Ernst, JIAN WANG, ZHAVERI, Darshana, SALITURO, Francesco G, BRITT, Shawn D, COCHRAN, John, CONNORS, Martin, HARRINGTON, Edmund M, HOOCK, Thomas, MARKLAND, William, NANTHAKUMAR, Suganthini, TASLIMI, Paul

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Parallel Dimers and Anti-parallel Tetramers Formed by Epidermal Growth Factor Receptor Pathway Substrate Clone 15 (EPS15) von Cupers, Philippe, ter Haar, Ernst, Boll, Werner, Kirchhausen, Tomas

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Computational and molecular modeling evaluation of the structural basis for tubulin polymerization inhibition by colchicine site agents von ter Haar, Ernst, Rosenkranz, Herbert S., Hamel, Ernest, Day, Billy W.

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Fragment-Based Discovery of Dual JC Virus and BK Virus Helicase Inhibitors von Bonafoux, Dominique, Nanthakumar, Suganthini, Bandarage, Upul K, Memmott, Christine, Lowe, Derek, Aronov, Alex M, Bhisetti, Govinda Rao, Bonanno, Kenneth C, Coll, Joyce, Leeman, Joshua, Lepre, Christopher A, Lu, Fan, Perola, Emanuele, Rijnbrand, Rene, Taylor, William P, Wilson, Dean, Zhou, Yi, Zwahlen, Jacque, ter Haar, Ernst

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Structure-Guided Design of Potent and Selective Pyrimidylpyrrole Inhibitors of Extracellular Signal-Regulated Kinase (ERK) Using Conformational Control von Aronov, Alex M, Tang, Qing, Martinez-Botella, Gabriel, Bemis, Guy W, Cao, Jingrong, Chen, Guanjing, Ewing, Nigel P, Ford, Pamella J, Germann, Ursula A, Green, Jeremy, Hale, Michael R, Jacobs, Marc, Janetka, James W, Maltais, Francois, Markland, William, Namchuk, Mark N, Nanthakumar, Suganthini, Poondru, Srinivasu, Straub, Judy, ter Haar, Ernst, Xie, Xiaoling

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Insights into regioselective metabolism of mefenamic acid by cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculations von Capoferri, Luigi, Leth, Rasmus, ter Haar, Ernst, Mohanty, Arun K., Grootenhuis, Peter D. J., Vottero, Eduardo, Commandeur, Jan N. M., Vermeulen, Nico P. E., Jørgensen, Flemming Steen, Olsen, Lars, Geerke, Daan P.

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The potent microtubule-stabilizing agent (+)-discodermolide induces apoptosis in human breast carcinoma cells—preliminary comparisons to paclitaxel von Balachandran, Raghavan, Haar, Ernst ter, Welsh, Manda J, Grant, Stephen G, Day, Billy W

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Molecular Locomotion: Modeling the Functional Domains of E1 Helicase to Assess the Asymmetric Rotary Model of E1 Helicase von Rokous, Judy, Bailey, Lily, Bradford, Nora, Chigler, Simon, Gustafson, John, Iyer, Hansika, Liapin, Michael, Sherrin, McClean, Zhan, Bowen, ter Haar, Ernst

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Insights into regioselective metabolism of mefenamic acid by cytochrome P 450 BM 3 mutants through crystallography, docking, molecular dynamics, and free energy calculations von Capoferri, Luigi, Leth, Rasmus, ter Haar, Ernst, Mohanty, Arun K., Grootenhuis, Peter D. J., Vottero, Eduardo, Commandeur, Jan N. M., Vermeulen, Nico P. E., Jørgensen, Flemming Steen, Olsen, Lars, Geerke, Daan P.

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Atomic Structure of Clathrin: A β Propeller Terminal Domain Joins an α Zigzag Linker von ter Haar, Ernst, Musacchio, Andrea, Harrison, Stephen C, Kirchhausen, Tomas

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Structure of GSK3β reveals a primed phosphorylation mechanism von ter Haar, Ernst, Coll, Joyce T, Austen, Douglas A, Hsiao, Hsun-Mei, Swenson, Lora, Jain, Jugnu

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3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3b von Arnost, Michael, Pierce, Al, Ter Haar, Ernst, Lauffer, David, Madden, Jaren, Tanner, Kirk, Green, Jeremy

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Discodermolide, A Cytotoxic Marine Agent That Stabilizes Microtubules More Potently Than Taxol von ter Haar, Ernst, Kowalski, Richard J, Hamel, Ernest, Lin, Chii M, Longley, Ross E, Gunasekera, Sarath P, Rosenkranz, Herbert S, Day, Billy W

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3-Aryl-4-(arylhydrazono)-1 H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3β von Arnost, Michael, Pierce, Al, Haar, Ernst ter, Lauffer, David, Madden, Jaren, Tanner, Kirk, Green, Jeremy

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Crystal structure of the p38α-MAPKAP kinase 2 heterodimer. VOLUME 282 (2007) PAGES 9733-9739 von Haar, Ernst ter, Prabhakar, Prakash, Liu, Xun, Lepre, Christopher

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