4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors von Churcher, Ian, Beher, Dirk, Best, Jonathan D., Castro, José L., Clarke, Earl E., Gentry, Amy, Harrison, Timothy, Hitzel, Laure, Kay, Euan, Kerrad, Sonia, Lewis, Huw D., Morentin-Gutierrez, Pablo, Mortishire-Smith, Russell, Oakley, Paul J., Reilly, Michael, Shaw, Duncan E., Shearman, Mark S., Teall, Martin R., Williams, Susie, Wrigley, Jonathan D.J.

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A new series of potent benzodiazepine γ-secretase inhibitors von Churcher, Ian, Ashton, Kate, Butcher, John W., Clarke, Earl E., Harrison, Timothy, Lewis, Huw D., Owens, Andrew P., Teall, Martin R., Williams, Susie, Wrigley, Jonathan D.J.

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Discovery and Characterization of Novel CNS-Penetrant GPR55 Agonists von Hewer, Richard C., Christie, Louisa A., Doyle, Kevin J., Xu, Xiao, Roberts, Maxine J., Dickson, Louise, Cheung, Toni, Cadwalladr, David H., Pickford, Philip, Teall, Martin, Powell, Justin A. C., Sheardown, Steven, Narayana, Lakshminarayana, Brice, Nicola L., Dawson, Lee A., Carlton, Mark, Bürli, Roland W.

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Discovery of CVN417, a Novel Brain-Penetrant α6-Containing Nicotinic Receptor Antagonist for the Modulation of Motor Dysfunction von Christie, Louisa A., Brice, Nicola L., Rowland, Anna, Dickson, Louise, Anand, Rishi, Teall, Martin, Doyle, Kevin J., Narayana, Lakshminarayana, Mitchell, Christine, Harvey, Jenna R. M., Mulligan, Victoria, Dawson, Lee A., Cragg, Stephanie J., Carlton, Mark, Bürli, Roland W.

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Characterisation of C101248: A novel selective THIK-1 channel inhibitor for the modulation of microglial NLRP3-inflammasome von Ossola, Bernardino, Rifat, Ali, Rowland, Anna, Hunter, Helen, Drinkall, Samuel, Bender, Clare, Hamlischer, Mayida, Teall, Martin, Burley, Russell, Barker, Daneil F., Cadwalladr, David, Dickson, Louise, Lawrence, Jason M.K., Harvey, Jenna R.M., Lizio, Marina, Xu, Xiao, Kavanagh, Edel, Cheung, Toni, Sheardown, Steve, Lawrence, Catherine B., Harte, Michael, Brough, David, Madry, Christian, Matthews, Kim, Doyle, Kevin, Page, Keith, Powell, Justin, Brice, Nicola L., Bürli, Roland W., Carlton, Mark B., Dawson, Lee A.

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Synthesis and SAR of novel GPR39 agonists and positive allosteric modulators von Burley, Russell, Hewer, Richard C., Teall, Martin, Dickson, Louise, Ossola, Bernardino, Russell, Sam, Bender, Clare, Cheung, Toni, Powell, Justin A.C., Xu, Xiao, Brice, Nicola L., Otter, Lucy, Arimont, Marta, Kidd, Sarah L., Vidal, David, Dale, James W., Mervin, Lewis, Sore, Hannah F., Mateu, Natalia, Lakshminarayana, Narayana, Dawson, Lee A., Carlton, Mark, Bürli, Roland W.

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Discovery of CVN293, a Brain Permeable KCNK13 (THIK-1) Inhibitor Suitable for Clinical Assessment von Bürli, Roland W., Doyle, Kevin J., Dickson, Louise, Rowland, Anna, Matthews, Kim, Stott, Andrew J., Teall, Martin, Ossola, Bernardino, Russell, Samuel G., Harvey, Jenna R. M., Wu, Yiming, Narayana, Lakshminarayana, Brice, Nicola L., Carlton, Mark, Dawson, Lee A.

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Discovery of CVN636: A Highly Potent, Selective, and CNS Penetrant mGluR7 Allosteric Agonist von Dickson, Louise, Teall, Martin, Chevalier, Elodie, Cheung, Toni, Liwicki, Gemma M., Mack, Stephen, Stephenson, Anne, White, Kathryn, Fosbeary, Richard, Harrison, David C., Brice, Nicola L., Doyle, Kevin, Ciccocioppo, Roberto, Wu, Chaobo, Almond, Sarah, Patel, Toshal R., Mitchell, Philip, Barnes, Matt, Ayscough, Andrew P., Dawson, Lee A., Carlton, Mark, Bürli, Roland W.

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Novel TRPM8 Antagonist Attenuates Cold Hypersensitivity after Peripheral Nerve Injury in Rats von Patel, Ryan, Gonçalves, Leonor, Newman, Robert, Jiang, Feng Li, Goldby, Anne, Reeve, Jennifer, Hendrick, Alan, Teall, Martin, Hannah, Duncan, Almond, Sarah, Brice, Nicola, Dickenson, Anthony H.

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Discovery of CVN636 : A Highly Potent, Selective, and CNS Penetrant mGluR 7 Allosteric Agonist von Dickson, Louise, Teall, Martin, Chevalier, Elodie, Cheung, Toni, Liwicki, Gemma M, Mack, Stephen, Stephenson, Anne, White, Kathryn, Fosbeary, Richard, Harrison, David C, Brice, Nicola L, Doyle, Kevin, Ciccocioppo, Roberto, Wu, Chaobo, Almond, Sarah, Patel, Toshal R, Mitchell, Philip, Barnes, Matt, Ayscough, Andrew P, Dawson, Lee A, Carlton, Mark, Bürli, Roland W

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Aryl sulfones: a new class of γ-secretase inhibitors von Teall, Martin, Oakley, Paul, Harrison, Timothy, Shaw, Duncan, Kay, Euan, Elliott, Jason, Gerhard, Ute, Castro, José L., Shearman, Mark, Ball, Richard G., Tsou, Nancy N.

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1-SULFONYL PIPERIDINE DERIVATIVES AS MODULATORS OF PROKINETICIN RECEPTORS von TEALL, MARTIN

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1-sulfonyl piperidine derivatives as modulators of prokineticin receptors von Teall, Martin

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1-sulfonyl piperidine derivatives as modulators of prokineticin receptors von Teall, Martin

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1-SULFONYL PIPERIDINE DERIVATIVES AS MODULATORS OF PROKINETICIN RECEPTORS von Teall, Martin

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1-sulfonyl piperidine derivatives as modulators of prokineticin receptors von Teall, Martin

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Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases von Carroll, Colm, Goldby, Anne, Teall, Martin

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1-SULFONYL PIPERIDINE DERIVATIVES AS MODULATORS OF PROKINETICIN RECEPTORS von TEALL, Martin

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NOVEL COMPOUNDS von Doyle, Kevin, Burli, Roland Werner, Teall, Martin

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NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY von TEALL, Martin, BÜRLI, Roland, DOYLE, Kevin

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